Exome sequencing identifies highly recurrent somatic GATA2 and CEBPA mutations in acute erythroid leukemia (Q38759271)

6 September 2017

title

Exome sequencing identifies highly recurrent somatic GATA2 and CEBPA mutations in acute erythroid leukemia (English)

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6 September 2017

N Ping

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6 September 2017

A Sun

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6 September 2017

Y Song

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6 September 2017

Q Wang

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6 September 2017

J Yin

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6 September 2017

W Cheng

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6 September 2017

Y Xu

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6 September 2017

L Wen

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6 September 2017

H Yao

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6 September 2017

L Ma

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6 September 2017

H Qiu

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6 September 2017

C Ruan

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6 September 2017

D Wu

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6 September 2017

S Chen

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6 September 2017

publication date

8 July 2016

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

page(s)

195-202

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Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group

6 September 2017

cites work

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DNMT3A Mutations in Acute Myeloid Leukemia

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Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

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Frequent pathway mutations of splicing machinery in myelodysplasia

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DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation

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GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells

21 January 2018

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High frequency of GATA2 mutations in patients with mild chronic neutropenia evolving to MonoMac syndrome, myelodysplasia, and acute myeloid leukemia.

21 January 2018

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An early haematopoietic defect in mice lacking the transcription factor GATA-2

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GATA Switches as Developmental Drivers

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GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation

21 January 2018

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GATA-2 regulates granulocyte-macrophage progenitor cell function

21 January 2018

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GATA-2 reinforces megakaryocyte development in the absence of GATA-1

21 January 2018

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Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

21 January 2018

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GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia

21 January 2018

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Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

21 January 2018

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GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity.

21 January 2018

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Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents

21 January 2018

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The evolution of cellular deficiency in GATA2 mutation

21 January 2018

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GATA zinc finger interactions modulate DNA binding and transactivation

21 January 2018

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12 December 2020

The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region.

1 reference

12 December 2020

Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation.

1 reference

12 December 2020

Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.

1 reference

12 December 2020

Identifiers

DOI

10.1038/LEU.2016.162

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Dimensions Publication ID

6 September 2017

1011023358

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