The bounty of nature for changing the cancer landscape (Q38707912)

5 September 2017

title

The bounty of nature for changing the cancer landscape (English)

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5 September 2017

Fazlul H Sarkar

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5 September 2017

Aamir Ahmad

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5 September 2017

Yiwei Li

series ordinal

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5 September 2017

language of work or name

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22 January 2016

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Molecular Nutrition and Food Research

5 September 2017

published in

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5 September 2017

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5 September 2017

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5 September 2017

page(s)

1251-1263

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5 September 2017

cites work

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Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate.

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Multitargeted therapy of cancer by green tea polyphenols

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Cancer and metastasis: prevention and treatment by green tea

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Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice

21 January 2018

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The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges

21 January 2018

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Fisetin: a dietary antioxidant for health promotion

21 January 2018

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Targeted regulation of PI3K/Akt/mTOR/NF-κB signaling by indole compounds and their derivatives: mechanistic details and biological implications for cancer therapy

21 January 2018

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Pomegranate extracts and cancer prevention: molecular and cellular activities

21 January 2018

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Perspectives on medicinal properties of plumbagin and its analogs

21 January 2018

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Dietary Glucosinolates Sulforaphane, Phenethyl Isothiocyanate, Indole-3-Carbinol/3,3'-Diindolylmethane: Anti-Oxidative Stress/Inflammation, Nrf2, Epigenetics/Epigenomics and In Vivo Cancer Chemopreventive Efficacy

21 January 2018

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Anticancer action of garcinol in vitro and in vivo is in part mediated through inhibition of STAT-3 signaling

21 January 2018

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Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs

21 January 2018

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Cancer chemoprevention by targeting the epigenome.

21 January 2018

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Cancer chemoprevention and nutriepigenetics: state of the art and future challenges

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

Impact of Epigenetic Dietary Components on Cancer through Histone Modifications

21 January 2018

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DNA methylation screening identifies driver epigenetic events of cancer cell survival

21 January 2018

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Epigenetic modifications of Nrf2 by 3,3'-diindolylmethane in vitro in TRAMP C1 cell line and in vivo TRAMP prostate tumors.

21 January 2018

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Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells

21 January 2018

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Anti-Tumor Activity of a Novel Compound-CDF Is Mediated by Regulating miR-21, miR-200, and PTEN in Pancreatic Cancer

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

Curcumin analogue CDF inhibits pancreatic tumor growth by switching on suppressor microRNAs and attenuating EZH2 expression

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM

21 January 2018

1 reference

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Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

21 January 2018

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Targeting of aryl hydrocarbon receptor-mediated activation of cyclooxygenase-2 expression by the indole-3-carbinol metabolite 3,3'-diindolylmethane in breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

p300/CBP dependent hyperacetylation of histone potentiates anticancer activity of gefitinib nanoparticles

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

A naturally-occurring histone acetyltransferase inhibitor derived from Garcinia indica impairs newly acquired and reactivated fear memories

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

Histone acetyl transferases as emerging drug targets.

21 January 2018

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https://api.crossref.org/works/10.1002%2FMNFR.201500867

Histone deacetylase inhibitors induce epithelial-to-mesenchymal transition in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Diindolilmethane (DIM) selectively inhibits cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

3,3'-Diindolylmethane (DIM) inhibits the growth and invasion of drug-resistant human cancer cells expressing EGFR mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Down-regulation of c-FLIP contributes to the sensitization effect of 3,3'-diindolylmethane on TRAIL-induced apoptosis in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

3, 3'-Diindolylmethane enhances the effectiveness of herceptin against HER-2/neu-expressing breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

3,3'-diindolylmethane and paclitaxel act synergistically to promote apoptosis in HER2/Neu human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Elimination of Colon Cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Hypoxia induced aggressiveness of prostate cancer cells is linked with deregulated expression of VEGF, IL-6 and miRNAs that are attenuated by CDF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Liposome encapsulated curcumin-difluorinated (CDF) inhibits the growth of cisplatin resistant head and neck cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Hyaluronic Acid Engineered Nanomicelles Loaded with 3,4-Difluorobenzylidene Curcumin for Targeted Killing of CD44+ Stem-Like Pancreatic Cancer Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Hyaluronic acid-conjugated polyamidoamine dendrimers for targeted delivery of 3,4-difluorobenzylidene curcumin to CD44 overexpressing pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Androgen receptor splice variants contribute to prostate cancer aggressiveness through induction of EMT and expression of stem cell marker genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Difluorinated-curcumin (CDF) restores PTEN expression in colon cancer cells by down-regulating miR-21

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

3'3-Diindolylmethane inhibits migration, invasion and metastasis of hepatocellular carcinoma by suppressing FAK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

NF-kappaB and epithelial to mesenchymal transition of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

The novel role of Yin Yang 1 in the regulation of epithelial to mesenchymal transition in cancer via the dysregulated NF-κB/Snail/YY1/RKIP/PTEN Circuitry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Attenuation of multi-targeted proliferation-linked signaling by 3,3′-diindolylmethane (DIM): From bench to clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

The dietary phytochemical 3,3'-diindolylmethane induces G2/M arrest and apoptosis in oral squamous cell carcinoma by modulating Akt-NF-κB, MAPK, and p53 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

In vivo and in vitro study on the role of 3,3'-diindolylmethane in treatment and prevention of nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Dietary diindolylmethane suppresses inflammation-driven lung squamous cell carcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Fluorocurcumins as cyclooxygenase-2 inhibitor: molecular docking, pharmacokinetics and tissue distribution in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Difluorinated-Curcumin (CDF): A Novel Curcumin Analog is a Potent Inhibitor of Colon Cancer Stem-Like Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Garcinol regulates EMT and Wnt signaling pathways in vitro and in vivo, leading to anticancer activity against breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Garcinol sensitizes human pancreatic adenocarcinoma cells to gemcitabine in association with microRNA signatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Epigenetic regulation of miRNA-cancer stem cells nexus by nutraceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Down-regulation of miR-21 Induces Differentiation of Chemoresistant Colon Cancer Cells and Enhances Susceptibility to Therapeutic Regimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

miR-146a suppresses invasion of pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Deregulation of miR-146a expression in a mouse model of pancreatic cancer affecting EGFR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Aryl hydrocarbon receptor-microRNA-212/132 axis in human breast cancer suppresses metastasis by targeting SOX4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

3,3'-diindolylmethane ameliorates experimental autoimmune encephalomyelitis by promoting cell cycle arrest and apoptosis in activated T cells through microRNA signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

MicroRNA-21 and the clinical outcomes of various carcinomas: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

MicroRNA-21: a therapeutic target for reversing drug resistance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

3,3'-Diindolylmethane ameliorates experimental hepatic fibrosis via inhibiting miR-21 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Restoring TGFβ1 pathway-related microRNAs: possible impact in metastatic prostate cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

3,3'-Diindolylmethane attenuates LPS-mediated acute liver failure by regulating miRNAs to target IRAK4 and suppress Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

The repressive effect of miR-148a on TGF beta-SMADs signal pathway is involved in the glabridin-induced inhibition of the cancer stem cells-like properties in hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Oncogenic MicroRNA-27a is a target for genistein in ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Genistein inhibits cell growth and invasion through regulation of miR-27a in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Genistein inhibits cell growth and induces apoptosis through up-regulation of miR-34a in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Genistein inhibits prostate cancer cell growth by targeting miR-34a and oncogenic HOTAIR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Genistein suppresses prostate cancer growth through inhibition of oncogenic microRNA-151.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

MicroRNAs 221/222 and Genistein-Mediated Regulation of ARHI Tumor Suppressor Gene in Prostate Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Genistein down-regulates miR-223 expression in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Genistein up-regulates tumor suppressor microRNA-574-3p in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Epigenetic deregulation of miR-29a and miR-1256 by isoflavone contributes to the inhibition of prostate cancer cell growth and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Up-regulation of miR-146a contributes to the inhibition of invasion of pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

EGCG enhances the efficacy of cisplatin by downregulating hsa-miR-98-5p in NSCLC A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Overexpression of miR-7-1 increases efficacy of green tea polyphenols for induction of apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-DZ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Overexpression of miR-126 sensitizes osteosarcoma cells to apoptosis induced by epigallocatechin-3-gallate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Proto-oncogenic isoform A2 of eukaryotic translation elongation factor eEF1 is a target of miR-663 and miR-744

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Cytotoxicity of pomegranate polyphenolics in breast cancer cells in vitro and vivo: potential role of miRNA-27a and miRNA-155 in cell survival and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Sulforaphane enhances temozolomide-induced apoptosis because of down-regulation of miR-21 via Wnt/β-catenin signaling in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Downregulation of miR-140 promotes cancer stem cell formation in basal-like early stage breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Inclusion complex of novel curcumin analogue CDF and β-cyclodextrin (1:2) and its enhanced in vivo anticancer activity against pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Introducing nanochemoprevention as a novel approach for cancer control: proof of principle with green tea polyphenol epigallocatechin-3-gallate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Nanochemoprevention by bioactive food components: a perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Nanochemoprevention: sustained release of bioactive food components for cancer prevention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Oral administration of naturally occurring chitosan-based nanoformulated green tea polyphenol EGCG effectively inhibits prostate cancer cell growth in a xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

Resveratrol nanoformulation for cancer prevention and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMNFR.201500867

21 January 2018

Identifiers

DOI

10.1002/MNFR.201500867

1 reference

5 September 2017

1 reference