The late sodium current in heart failure: pathophysiology and clinical relevance (Q38611594)

https://api.crossref.org/works/10.1002%2FEHF2.12003

The late Na current as a therapeutic target: where are we?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

The role of late I Na in development of cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδ(C) can be reversed by inhibition of late Na(+) current

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Enhancing mitochondrial Ca2+ uptake in myocytes from failing hearts restores energy supply and demand matching

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A multi-modal composition of the late Na+ current in human ventricular cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A single Na(+) channel mutation causing both long-QT and Brugada syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Late sodium current in failing heart: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Late Na+ current produced by human cardiac Na+ channel isoform Nav1.5 is modulated by its beta1 subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Increased late sodium current in myocytes from a canine heart failure model and from failing human heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Increased late sodium current in left atrial myocytes of rabbits with left ventricular hypertrophy: its role in the genesis of atrial arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Simulation and mechanistic investigation of the arrhythmogenic role of the late sodium current in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

An increase in late sodium current potentiates the proarrhythmic activities of low-risk QT-prolonging drugs in female rabbit hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Pharmacological modulation of ion channels and transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Reducing the Late Sodium Current Improves Cardiac Function during Sodium Pump Inhibition by Ouabain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Suppression of Re-Entrant and Multifocal Ventricular Fibrillation by the Late Sodium Current Blocker Ranolazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

The late Na+ current--origin and pathophysiological relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Novel, ultraslow inactivating sodium current in human ventricular cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Sodium channel mutations and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Characterization of human cardiac Na+ channel mutations in the congenital long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Non-equilibrium gating in cardiac Na+ channels: an original mechanism of arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Dynamics of the late Na(+) current during cardiac action potential and its contribution to afterdepolarizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A sodium channel mutation causing epilepsy in man exhibits subtle defects in fast inactivation and activation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Intracardiac conduction defects in dystrophia myotonica. Electrophysiological study of 12 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

About half of the late sodium current in cardiac myocytes from dog ventricle is due to non-cardiac-type Na(+) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Blocking Scn10a channels in heart reduces late sodium current and is antiarrhythmic

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Contribution of neuronal sodium channels to the cardiac fast sodium current INa is greater in dog heart Purkinje fibers than in ventricles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Late sodium current and its contribution to action potential configuration in guinea pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

An unexpected requirement for brain-type sodium channels for control of heart rate in the mouse sinoatrial node

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Larger late sodium current density as well as greater sensitivities to ATX II and ranolazine in rabbit left atrial than left ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Role of late sodium channel current block in the management of atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Na⁺ transport in the normal and failing heart - remember the balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

The arrhythmogenic consequences of increasing late INa in the cardiomyocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Na(+) current in human ventricle: implications for sodium loading and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Regulation kinetics of Na+-Ca2+ exchange current in guinea-pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Cardiac Na+-Ca2+ exchanger: dynamics of Ca2+-dependent activation and deactivation in intact myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

The role of Na-Ca exchange current in the cardiac action potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Control of L-type calcium current during the action potential of guinea-pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Profile of L-type Ca(2+) current and Na(+)/Ca(2+) exchange current during cardiac action potential in ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Endocardial versus epicardial differences in L-type calcium current in canine ventricular myocytes studied by action potential voltage clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Calcium/calmodulin-dependent kinase II regulation of cardiac ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

CaMKII regulation of voltage-gated sodium channels and cell excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Regulation of sodium channel activity by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A calcium sensor in the sodium channel modulates cardiac excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Calmodulin mediates Ca2+ sensitivity of sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Calcium-mediated dual-mode regulation of cardiac sodium channel gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Crystallographic basis for calcium regulation of sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Sodium channel inactivation: molecular determinants and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Solution NMR Structure of Apo-Calmodulin in Complex with the IQ Motif of Human Cardiac Sodium Channel NaV1.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Role of Ca2+/calmodulin-dependent protein kinase II in cardiac hypertrophy and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

CaMKII-dependent regulation of cardiac Na(+) homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Calmodulin kinase II and protein kinase C mediate the effect of increased intracellular calcium to augment late sodium current in rabbit ventricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Quantitation of protein kinase A-mediated trafficking of cardiac sodium channels in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Regulation of caveolar cardiac sodium current by a single Gsalpha histidine residue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts--role of late sodium current and intracellular ion accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Antagonism by ranolazine of the pro-arrhythmic effects of increasing late INa in guinea pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Redox regulation of sodium and calcium handling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Extracellular proton depression of peak and late Na⁺ current in the canine left ventricle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Extracellular proton modulation of the cardiac voltage-gated sodium channel, Nav1.5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Proton sensors in the pore domain of the cardiac voltage-gated sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Extracellular protons inhibit charge immobilization in the cardiac voltage-gated sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Redox reaction modulates transient and persistent sodium current during hypoxia in guinea pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Persistent sodium current and Na+/H+ exchange contributes to the augmentation of the reverse Na+/Ca2+ exchange during hypoxia or acute ischemia in ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Hypoxia. 4. Hypoxia and ion channel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Hypoxia increases persistent sodium current in rat ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Hypoxia and persistent sodium current.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Modulation of cardiac sodium channel gating by lysophosphatidylcholine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Direct protective effects of poly-unsaturated fatty acids, DHA and EPA, against activation of cardiac late sodium current: a mechanism for ischemia selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Caveolin-3 suppresses late sodium current by inhibiting nNOS-dependent S-nitrosylation of SCN5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Alternative promoter usage and splicing of the human SCN5A gene contribute to transcript heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Cloning and initial characterization of the human cardiac sodium channel (SCN5A) promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Glycosylation influences voltage-dependent gating of cardiac and skeletal muscle sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A double tyrosine motif in the cardiac sodium channel domain III-IV linker couples calcium-dependent calmodulin binding to inactivation gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Modulation of the cardiac sodium channel NaV1.5 by Fyn, a Src family tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

The cardiac sodium channel is post-translationally modified by arginine methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Mechanosensitivity of Nav1.5, a voltage-sensitive sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine decreases mechanosensitivity of the voltage-gated sodium ion channel Na(v)1.5: a novel mechanism of drug action

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Mechanochemotransduction during cardiomyocyte contraction is mediated by localized nitric oxide signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Alterations of sodium channel kinetics and gene expression in the postinfarction remodeled myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

CaMKII Inhibition in Heart Failure Makes Jump to Human

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Regulation of Ca2+ and Na+ in normal and failing cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Selective inhibition of sodium-calcium exchanger by SEA-0400 decreases early and delayed after depolarization in canine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Cardiac excitation-contraction coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Late sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Differences in action potential and early afterdepolarization properties in LQT2 and LQT3 models of long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

The genetic basis of long QT and short QT syndromes: a mutation update

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Increased late sodium current contributes to long QT-related arrhythmia susceptibility in female mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Drug-induced long-QT syndrome associated with a subclinical SCN5A mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A novel SCN5A mutation associated with the linker between III and IV domains of Nav1.5 in a neonate with fatal long QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Modulation of ryanodine receptor by luminal calcium and accessory proteins in health and cardiac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Mitochondria and arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine improves abnormal repolarization and contraction in left ventricular myocytes of dogs with heart failure by inhibiting late sodium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine for the treatment of chronic angina and potential use in other cardiovascular conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

F 15845 inhibits persistent sodium current in the heart and prevents angina in animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Antiarrhythmic effects of the highly selective late sodium channel current blocker GS-458967

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine inhibits an oxidative stress-induced increase in myocyte sodium and calcium loading during simulated-demand ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine bromhydrate (F 15845) prevents ischemia-induced heart remodeling by reduction of the intracellular Na+ overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

A study of the effects of ranolazine using automated quantitative analysis of serial myocardial perfusion images

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Cardioprotective effects of ranolazine (RS-43285) in the isolated perfused rabbit heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine decreases diastolic calcium accumulation caused by ATX-II or ischemia in rat hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

The late Na+ current (INa) inhibitor ranolazine attenuates effects of palmitoyl-L-carnitine to increase late INa and cause ventricular diastolic dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine improves diastolic function in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Short-term treatment with ranolazine improves mechanical efficiency in dogs with chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Antianginal efficacy of ranolazine when added to treatment with amlodipine: the ERICA (Efficacy of Ranolazine in Chronic Angina) trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Comparative efficacy of ranolazine versus atenolol for chronic angina pectoris

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Effects of ranolazine on recurrent cardiovascular events in patients with non-ST-elevation acute coronary syndromes: the MERLIN-TIMI 36 randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Use of ranolazine in patients with incomplete revascularization after percutaneous coronary intervention: design and rationale of the Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (RIVER-PCI) trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Effect of ranolazine on left ventricular dyssynchrony in patients with coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

B-type natriuretic peptide and the effect of ranolazine in patients with non-ST-segment elevation acute coronary syndromes: observations from the MERLIN-TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Corona

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

RAnoLazIne for the treatment of diastolic heart failure in patients with preserved ejection fraction: the RALI-DHF proof-of-concept study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Evaluative framework for phase II studies in patients with heart failure and preserved ejection fraction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

Inhibition of late (sustained/ persistent) sodium current: a potential drug target to reduce intracellular sodium-dependent calcium overload and its detrimental effects on cardiomyocyte function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

CrossTalk proposal: The late sodium current is an important player in the development of diastolic heart failure (heart failure with a preserved ejection fraction)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Increased late sodium currents are related to transcription of neuronal isoforms in a pressure-overload model

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Regulation of voltage-gated cardiac sodium current by epidermal growth factor receptor kinase in guinea pig ventricular myocytes

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Divergent action potential morphologies reveal nonequilibrium properties of human cardiac Na channels

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Paramyotonia congenita with an SCN4A mutation affecting cardiac repolarization

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Contribution of I Ks to ventricular repolarization in canine myocytes

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Reopening of L-type calcium channels in human ventricular myocytes during applied epicardial action potentials

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Cardiac ionic currents and acute ischemia: from channels to arrhythmias

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Induction of persistent sodium current by exogenous and endogenous nitric oxide

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Partial characterization of the rH1 sodium channel protein from rat heart using subtype-specific antibodies

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

High intracellular Na+ preserves myocardial function at low heart rates in isolated myocardium from failing hearts

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Gating of the late Na+ channel in normal and failing human myocardium

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failure

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Double-blind efficacy and safety study of a novel anti-ischemic agent, ranolazine, versus placebo in patients with chronic stable angina pectoris. Ranolazine Study Group

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the Metabolic Efficiency With Ranolazine for Less

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Effects of ranolazine on left ventricular regional diastolic function in patients with ischemic heart disease

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

Improvement in left ventricular systolic and diastolic performance during ranolazine treatment in patients with stable angina

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021

CrossTalk opposing view: the late sodium current is not an important player in the development of diastolic heart failure (heart failure with a preserved ejection fraction)

1 reference

https://api.crossref.org/works/10.1002%2FEHF2.12003

7 January 2021