Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways (Q38605378)

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scientific article published on 03 March 2008

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English	Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways	scientific article published on 03 March 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

4 September 2017

Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways (English)

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Europe PubMed Central

PMC publication ID

4 September 2017

dilated cardiomyopathy

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based on heuristic

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author name string

Maria I Kontaridis

1

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Europe PubMed Central

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4 September 2017

Wentian Yang

2

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4 September 2017

Kendra K Bence

3

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4 September 2017

Darragh Cullen

4

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4 September 2017

Bo Wang

5

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4 September 2017

Natalya Bodyak

6

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Europe PubMed Central

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4 September 2017

Qingen Ke

7

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Europe PubMed Central

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4 September 2017

Aleksander Hinek

8

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4 September 2017

Peter M Kang

9

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4 September 2017

Ronglih Liao

10

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4 September 2017

Benjamin G Neel

11

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4 September 2017

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publication date

3 March 2008

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4 September 2017

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4 September 2017

117

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4 September 2017

11

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Europe PubMed Central

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4 September 2017

1423-1435

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Europe PubMed Central

PMC publication ID

4 September 2017

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo

1 reference

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Gain-of-function RAF1 mutations cause Noonan and LEOPARD syndromes with hypertrophic cardiomyopathy

1 reference

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1 reference

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SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth

1 reference

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Regulation of cardiac hypertrophy by intracellular signalling pathways

1 reference

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LEOPARD syndrome: clinical diagnosis in the first year of life

1 reference

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Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling

1 reference

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PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects

1 reference

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Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease

1 reference

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PTPN11 mutations and genotype-phenotype correlations in Noonan and LEOPARD syndromes

1 reference

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Functional analysis of PTPN11/SHP-2 mutants identified in Noonan syndrome and childhood leukemia

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Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells

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Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation

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The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

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Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy

1 reference

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PTPN11 mutations in Noonan syndrome: molecular spectrum, genotype-phenotype correlation, and phenotypic heterogeneity

1 reference

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Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

1 reference

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Combinatorial control of the specificity of protein tyrosine phosphatases

1 reference

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Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation

1 reference

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Shp-2 tyrosine phosphatase: signaling one cell or many

1 reference

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1 reference

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Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway

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1 reference

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1 reference

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The Leopard (multiple lentigines) syndrome revisited

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https://pubmed.ncbi.nlm.nih.gov/18316486

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Noonan syndrome and aortic coarctation

1 reference

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A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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Identifiers

10.1161/CIRCULATIONAHA.107.728865

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

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