Mahogunin Ring Finger-1 (MGRN1), a Multifaceted Ubiquitin Ligase: Recent Unraveling of Neurobiological Mechanisms (Q38563041)

4 September 2017

1 reference

title

Mahogunin Ring Finger-1 (MGRN1), a Multifaceted Ubiquitin Ligase: Recent Unraveling of Neurobiological Mechanisms (English)

1 reference

4 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Arun Upadhyay

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Ayeman Amanullah

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Ribhav Mishra

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Amit Prasad

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Amit Mishra

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

publication date

9 August 2015

1 reference

4 September 2017

published in

Molecular Neurobiology

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31 May 2020

volume

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31 May 2020

issue

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31 May 2020

page(s)

4484-4496

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json

Protein folding and misfolding

31 May 2020

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Mahogunin ring finger-1 (MGRN1) E3 ubiquitin ligase inhibits signaling from melanocortin receptor by competition with Galphas

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The Arabidopsis RING E3 ubiquitin ligase AtAIRP3/LOG2 participates in positive regulation of high-salt and drought stress responses

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Functional conservation between mammalian MGRN1 and plant LOG2 ubiquitin ligases

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Abnormal regulation of TSG101 in mice with spongiform neurodegeneration

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RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

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Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

21 January 2018

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Principles of protein folding, misfolding and aggregation

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Modulation of neurodegeneration by molecular chaperones

21 January 2018

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Mechanisms of protein seeding in neurodegenerative diseases

21 January 2018

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Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

21 January 2018

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What is the basis of transmissible spongiform encephalopathy induced neurodegeneration and can it be repaired?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking

21 January 2018

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Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding

21 January 2018

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A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control

21 January 2018

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Human MDM2 isoforms translated differentially on constitutive versus p53-regulated transcripts have distinct functions in the p53/MDM2 and TSG101/MDM2 feedback control loops

21 January 2018

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Mitochondrial dysfunction precedes neurodegeneration in mahogunin (Mgrn1) mutant mice

21 January 2018

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Molecular biology of prion diseases

21 January 2018

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Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

21 January 2018

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Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration

21 January 2018

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Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease

21 January 2018

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Prions disturb post-Golgi trafficking of membrane proteins

21 January 2018

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Cellular prion protein (PrPC) of the neuron cell transformed to a PK-resistant protein under oxidative stress, comprising main mitochondrial damage in prion diseases

21 January 2018

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Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation

21 January 2018

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Interaction between misfolded PrP and the ubiquitin-proteasome system in prion-mediated neurodegeneration

21 January 2018

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21 January 2018

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Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

21 January 2018

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21 January 2018

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21 January 2018

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Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell

21 January 2018

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Role of the Human Heat Shock Protein hsp70 in Protection against Stress-Induced Apoptosis

21 January 2018

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21 January 2018

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Mahogunin ring finger-1 (MGRN1) suppresses chaperone-associated misfolded protein aggregation and toxicity.

21 January 2018

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21 January 2018

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

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p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

21 January 2018

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Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

21 January 2018

1 reference

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The Neuropathology of CAG Repeat Diseases: Review and Update of Genetic and Molecular Features

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Transcription factor sequestration by polyglutamine proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Transcriptional abnormalities in Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Biochemical and genetic studies of pigment-type switching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

The neuropathogenic contributions of lysosomal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Lysosomes in iron metabolism, ageing and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

The protein import machinery of mitochondria-a regulatory hub in metabolism, stress, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Mitochondria take center stage in aging and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Relationship between asymmetric nodal expression and the direction of embryonic turning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

The left-right axis in the mouse: from origin to morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Compromised autophagy and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Drug transport in brain via the cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Inducers and co-inducers of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Molecular chaperone inducers in medicine and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Autophagy coupling interplay: can improve cellular repair and aging?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Chemical inducers of targeted protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Functional analysis of the RING-type ubiquitin ligase family of Arabidopsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

21 January 2018

1 reference

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The Jalview Java alignment editor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

MGRN1-dependent pigment-type switching requires its ubiquitination activity but not its interaction with TSG101 or NEDD4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Mahogunin-mediated α-tubulin ubiquitination via noncanonical K6 linkage regulates microtubule stability and mitotic spindle orientation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-015-9379-8

Genetic Studies of the Mouse Mutations mahogany and mahoganoid

21 January 2018

1 reference

12 December 2020

The effect of mahogunin gene mutant on reproduction in male mice: a new sight for infertility?

1 reference

12 December 2020

Targeting of the prion protein to the cytosol: mechanisms and consequences

1 reference

12 December 2020

Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies).

1 reference

12 December 2020

The E3 ubiquitin ligase Mahogunin ubiquitinates the melanocortin 2 receptor

1 reference

12 December 2020

Relationship between the proteasomal system and autophagy

1 reference

12 December 2020

Identification and quantitation of levels of protein synthesis initiation factors in crude HeLa cell lysates by two-dimensional polyacrylamide gel electrophoresis

1 reference

12 December 2020

Piecing together the pigment-type switching puzzle

1 reference

12 December 2020

Post-translational modification: Sweetening protein quality control

1 reference

12 December 2020

Vacuolating encephalitis in mice infected by human coronavirus OC43

1 reference

12 December 2020

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein

1 reference

12 December 2020

Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity

1 reference

12 December 2020

Low micromolar levels of hydrogen peroxide and proteasome inhibitors induce the 60-kDa A170 stress protein in murine peritoneal macrophages

1 reference

12 December 2020

p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells

1 reference

12 December 2020

10.1007/S12035-015-9379-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

1042856739

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255182%20AND%20SRC:MED&resulttype=core&format=json