Gene set enrichment analysis of the NF-κB/Snail/YY1/RKIP circuitry in multiple myeloma. (Q38480261)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24481661%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Gene set enrichment analysis of the NF-κB/Snail/YY1/RKIP circuitry in multiple myeloma (English)

1 reference

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6 March 2020

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1 reference

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6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24481661%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24481661%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

Peggy Kanellou

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6 March 2020

publication date

31 January 2014

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6 March 2020

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6 March 2020

volume

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6 March 2020

issue

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6 March 2020

page(s)

4987-5005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24481661%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Focus on multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

The Snail genes as inducers of cell movement and survival: implications in development and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Inhibition of epithelial to mesenchymal transition in metastatic prostate cancer cells by the novel proteasome inhibitor, NPI-0052: pivotal roles of Snail repression and RKIP induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Nitric oxide sensitizes prostate carcinoma cell lines to TRAIL-mediated apoptosis via inactivation of NF-kappa B and inhibition of Bcl-xl expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Nitric oxide sensitizes tumor cells to TRAIL-induced apoptosis via inhibition of the DR5 transcription repressor Yin Yang 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Rituximab-induced inhibition of YY1 and Bcl-xL expression in Ramos non-Hodgkin's lymphoma cell line via inhibition of NF-kappa B activity: role of YY1 and Bcl-xL in Fas resistance and chemoresistance, respectively.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

The molecular classification of multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Spotlight on differentially expressed genes in urinary bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Expression of miRNAs involved in angiogenesis, tumor cell proliferation, tumor suppressor inhibition, epithelial-mesenchymal transition and activation of metastasis in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

WebGestalt: an integrated system for exploring gene sets in various biological contexts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Differential expression of microRNAs in adipose tissue after long-term high-fat diet-induced obesity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Identification of common differentially expressed genes in urinary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Gene expression profiling of B lymphocytes and plasma cells from Waldenström's macroglobulinemia: comparison with expression patterns of the same cell counterparts from chronic lymphocytic leukemia, multiple myeloma and normal individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

21 January 2018

Fibroblasts in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

NF-κB localization in multiple myeloma plasma cells and mesenchymal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Molecular mechanisms of novel therapeutic approaches for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Snail is a repressor of RKIP transcription in metastatic prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

NF-kappa B as a therapeutic target in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Dual inhibition of canonical and noncanonical NF-κB pathways demonstrates significant antitumor activities in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Snail1 transcriptional repressor binds to its own promoter and controls its expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Yin yang 1 regulates the expression of snail through a distal enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Expression of E-cadherin transcriptional regulators in ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Overexpression of NBS1 induces epithelial-mesenchymal transition and co-expression of NBS1 and Snail predicts metastasis of head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Overexpression of Yin Yang 1 in the pathogenesis of human hematopoietic malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Mcl-1 and YY1 inhibition and induction of DR5 by the BH3-mimetic Obatoclax (GX15-070) contribute in the sensitization of B-NHL cells to TRAIL apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Transcription factor YY1: structure, function, and therapeutic implications in cancer biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

The involvement of the transcription factor Yin Yang 1 in cancer development and progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Yin Yang 1 overexpression in diffuse large B-cell lymphoma is associated with B-cell transformation and tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Unique polycomb gene expression pattern in Hodgkin's lymphoma and Hodgkin's lymphoma-derived cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Gene expression profiling of Polycomb, Hox and Meis genes in patients with acute myeloid leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Clinical quantitation of diagnostic and predictive gene expression levels in follicular and diffuse large B-cell lymphoma by RT-PCR gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Yin yang 1 expression in human tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Yin Yang 1 as a prognostic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Transcriptional repression of Bim by a novel YY1-RelA complex is essential for the survival and growth of Multiple Myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

The novel role of Yin Yang 1 in the regulation of epithelial to mesenchymal transition in cancer via the dysregulated NF-κB/Snail/YY1/RKIP/PTEN Circuitry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Rapid evolution of a recently retroposed transcription factor YY2 in mammalian genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Yin Yang 2: the great unknown within the Yin Yang 1 regulatory network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

RKIP and BRAF aberrations in human nasal polyps and the adjacent turbinate mucosae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Implication of RAF and RKIP genes in urinary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

BRAF and RKIP are significantly decreased in cutaneous squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Loss of RAF kinase inhibitor protein is a somatic event in the pathogenesis of therapy-related acute myeloid leukemias with C-RAF germline mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Mutations inDNMT3A and loss of RKIP are independent events in acute monocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Reduction of Raf kinase inhibitor protein expression by Bcr-Abl contributes to chronic myelogenous leukemia proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Pivotal roles of snail inhibition and RKIP induction by the proteasome inhibitor NPI-0052 in tumor cell chemoimmunosensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Transfection with liver-type glutaminase cDNA alters gene expression and reduces survival, migration and proliferation of T98G glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Cocaine, Not Morphine, Causes the Generation of Reactive Oxygen Species and Activation of NF-κB in Transiently Cotransfected Heart Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Activation of multiple cancer pathways and tumor maintenance function of the 3q amplified oncogene FNDC3B

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Expression of tumor protein D52-like genes in childhood leukemia at diagnosis: clinical and sample considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

The tumor protein D52 family: many pieces, many puzzles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

A role for tumor protein TPD52 phosphorylation in endo-membrane trafficking during cytokinesis

21 January 2018

1 reference

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Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer

21 January 2018

1 reference

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The hD52 (TPD52) gene is a candidate target gene for events resulting in increased 8q21 copy number in human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Definition of the tumor protein D52 (TPD52) gene family through cloning of D52 homologues in human (hD53) and mouse (mD52)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

The functional interactome landscape of the human histone deacetylase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Searching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Microfibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Targeting MYC dependence in cancer by inhibiting BET bromodomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Aberrant epigenetic regulation of bromodomain BRD4 in human colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Suppression of inflammation by a synthetic histone mimic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

Transcriptional regulation of ATP2C1 gene by Sp1 and YY1 and reduced function of its promoter in Hailey-Hailey disease keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

The c-MYC-AP4-p21 cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-014-1659-9

BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma

21 January 2018

1 reference

12 December 2020

Rituximab (chimeric anti-CD20 monoclonal antibody) inhibits the constitutive nuclear factor-{kappa}B signaling pathway in non-Hodgkin's lymphoma B-cell lines: role in sensitization to chemotherapeutic drug-induced apoptosis.

1 reference

12 December 2020

Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis

1 reference

12 December 2020

Role of the angiogenic components, VEGFA, FGF2, OPN and RHOC, in urothelial cell carcinoma of the urinary bladder

1 reference

12 December 2020

Clinical Significance of Tumor Protein D52 Immunostaining in a Large Series of Ewing's Sarcoma Family of Tumors

1 reference

12 December 2020

Roles Each of Snail, Yin Yang 1 and RKIP in the Regulation of Tumor Cells Chemo-immuno-resistance to Apoptosis.

1 reference

12 December 2020

Treatment of multiple myeloma

1 reference

12 December 2020

Fibronectin is distinctly downregulated in murine mammary adenocarcinoma cells with high metastatic potential

1 reference

12 December 2020

Wnt-dependent regulation of the E-cadherin repressor snail

1 reference

12 December 2020

Multiple myeloma: diagnosis and treatment

1 reference

12 December 2020

Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma

1 reference

12 December 2020

Novel biological therapies for the treatment of multiple myeloma

1 reference

12 December 2020

Pathway simulations in common oncogenic drivers of leukemic and rhabdomyosarcoma cells: a systems biology approach.

1 reference

12 December 2020

10.1007/S13277-014-1659-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24481661%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 March 2020

1002895776

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24481661%20AND%20SRC:MED&resulttype=core&format=json