At the centennial of Michaelis and Menten, competing Michaelis-Menten steps explain effect of GLP-1 on blood-brain transfer and metabolism of glucose (Q38200704)

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scientific article published on 30 April 2014

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English	At the centennial of Michaelis and Menten, competing Michaelis-Menten steps explain effect of GLP-1 on blood-brain transfer and metabolism of glucose	scientific article published on 30 April 2014

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 August 2017

At the centennial of Michaelis and Menten, competing Michaelis-Menten steps explain effect of GLP-1 on blood-brain transfer and metabolism of glucose (English)

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Europe PubMed Central

PubMed publication ID

30 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

author name string

Michael Gejl

1

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Europe PubMed Central

PubMed publication ID

30 August 2017

Jørgen Rungby

2

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Europe PubMed Central

PubMed publication ID

30 August 2017

Birgitte Brock

3

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Europe PubMed Central

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30 August 2017

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publication date

30 April 2014

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Europe PubMed Central

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30 August 2017

Basic and Clinical Pharmacology and Toxicology

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Europe PubMed Central

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30 August 2017

115

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Europe PubMed Central

PubMed publication ID

30 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

162-171

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

Mechanisms linking obesity to insulin resistance and type 2 diabetes

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Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?

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Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes.

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The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

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Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

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Intensive versus conventional glucose control in critically ill patients

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Identical mRNA for preproglucagon in pancreas and gut.

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Neuroprotective properties of GLP-1: theoretical and practical applications

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Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans

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Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects

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Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

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The glucagon-like peptide-1 receptor--or not?

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The role of gut hormones in glucose homeostasis

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New developments in the incretin concept

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Glucagon-like peptide 1(GLP-1) in biology and pathology

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Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers

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Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucose-dependent insulin secretion and counterregulation during hypoglycemia

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21 January 2018

The Physiology of Glucagon-like Peptide 1

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No increased risk of hypoglycaemic episodes during 48 h of subcutaneous glucagon-like-peptide-1 administration in fasting healthy subjects

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21 January 2018

Glucagon-like peptide-1 (GLP-1) raises blood-brain glucose transfer capacity and hexokinase activity in human brain

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Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia

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Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes

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Incretin effects on β-cell function, replication, and mass: the human perspective

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GLP-1 and extra-islet effects

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Is the GLP-1 system a viable therapeutic target for weight reduction?

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How palatable food disrupts appetite regulation

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On the physiology of GIP and GLP-1.

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Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans

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21 January 2018

Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity

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Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons

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Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity

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Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling

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21 January 2018

Energy expenditure by intravenous administration of glucagon-like peptide-1 mediated by the lower brainstem and sympathoadrenal system

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21 January 2018

Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients

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21 January 2018

Exenatide alters myocardial glucose transport and uptake depending on insulin resistance and increases myocardial blood flow in patients with type 2 diabetes.

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21 January 2018

Incretin-based therapies: can we achieve glycemic control and cardioprotection?

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21 January 2018

Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system.

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Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences

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Neuronal and intracellular signaling pathways mediating GLP-1 energy balance and glycemic effects

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Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy

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21 January 2018

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10.1111/BCPT.12240

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 August 2017

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