The dual functions of YAP-1 to promote and inhibit cell growth in human malignancy (Q38171966)

30 August 2017

title

The dual functions of YAP-1 to promote and inhibit cell growth in human malignancy (English)

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30 August 2017

1 reference

Hai Wang

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30 August 2017

Yu-Chen Du

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30 August 2017

Xiao-Jun Zhou

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30 August 2017

Hong Liu

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30 August 2017

Shou-Ching Tang

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30 August 2017

publication date

1 March 2014

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Cancer and Metastasis Reviews

30 August 2017

published in

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30 August 2017

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30 August 2017

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30 August 2017

page(s)

173-181

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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

30 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Regulation of mouse embryonic stem cell self-renewal by a Yes–YAP–TEAD2 signaling pathway downstream of LIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Yes-associated protein (YAP) functions as a tumor suppressor in breast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

YAP: at the crossroad between transformation and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

TEAD mediates YAP-dependent gene induction and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Restriction of intestinal stem cell expansion and the regenerative response by YAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

TAZ interacts with zonula occludens‐1 and ‐2 proteins in a PDZ‐1 dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Evidence for a Growth-Stabilizing Regulatory Feedback Mechanism between Myc and Yorkie, the Drosophila Homolog of Yap

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Physical interaction with Yes-associated protein enhances p73 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

YAP1 increases organ size and expands undifferentiated progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Merlin in organ size control and tumorigenesis: Hippo versus EGFR?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

YAP is a candidate oncogene for esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Clinical significance of yes-associated protein overexpression in cervical carcinoma: the differential effects based on histotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

BAG-1, an anti-apoptotic tumour marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Loss of heterozygosity on chromosome 11 q in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Loss of Yes-associated protein (YAP) expression is associated with estrogen and progesterone receptors negativity in invasive breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Exploration of a new drug that targets YAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

Yes-Associated Protein (YAP) is a critical mediator of c-Jun-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-013-9463-3

10.1007/S10555-013-9463-3

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

30 August 2017

1027487070

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1 reference