Multiple conformational selection and induced fit events take place in allosteric propagation. (Q38163208)

PubMed publication ID

24239303

30 August 2017

title

Multiple conformational selection and induced fit events take place in allosteric propagation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

13 May 2020

Ruth Nussinov

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

13 May 2020

Chung-Jung Tsai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

13 May 2020

language of work or name

1 reference

31 October 2013

1 reference

PubMed publication ID

24239303

30 August 2017

published in

Biophysical Chemistry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

13 May 2020

volume

186

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

13 May 2020

page(s)

22-30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

Folding funnels, binding funnels, and protein function

13 May 2020

cites work

1 reference

12 December 2020

Folding and binding cascades: shifts in energy landscapes

1 reference

12 December 2020

Folding funnels and binding mechanisms

1 reference

12 December 2020

Evolutionarily conserved pathways of energetic connectivity in protein families

1 reference

12 December 2020

Folding and binding cascades: dynamic landscapes and population shifts

1 reference

12 December 2020

Anatomy of protein structures: visualizing how a one-dimensional protein chain folds into a three-dimensional shape

1 reference

12 December 2020

Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition

1 reference

12 December 2020

Two-state allosteric behavior in a single-domain signaling protein

1 reference

12 December 2020

Molecular recognition by induced fit: how fit is the concept?

1 reference

12 December 2020

Structured disorder and conformational selection

1 reference

12 December 2020

Multiple diverse ligands binding at a single protein site: a matter of pre-existing populations

1 reference

12 December 2020

Protein folding in the post-genomic era.

1 reference

12 December 2020

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

1 reference

12 December 2020

Is allostery an intrinsic property of all dynamic proteins?

1 reference

12 December 2020

Merging complexes: properties of membrane raft assembly during lymphocyte signaling

1 reference

12 December 2020

Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells

1 reference

12 December 2020

Analysis of allosterism in functional assays

1 reference

12 December 2020

Allosteric modulation of the cannabinoid CB1 receptor

1 reference

12 December 2020

Application of a Theory of Enzyme Specificity to Protein Synthesis

1 reference

12 December 2020

The Energy Landscapes and Motions of Proteins

1 reference

12 December 2020

Membrane phosphatidylserine regulates surface charge and protein localization

1 reference

12 December 2020

Allostery: absence of a change in shape does not imply that allostery is not at play

1 reference

12 December 2020

Allostery and cooperativity revisited

1 reference

12 December 2020

Allosteric regulation and catalysis emerge via a common route.

1 reference

12 December 2020

Selected-fit versus induced-fit protein binding: kinetic differences and mutational analysis.

1 reference

12 December 2020

Surface sites for engineering allosteric control in proteins

1 reference

12 December 2020

Signaling cross-talk between TGF-beta/BMP and other pathways

1 reference

12 December 2020

Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

1 reference

12 December 2020

Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

1 reference

12 December 2020

Frameworks for understanding long-range intra-protein communication

1 reference

12 December 2020

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

1 reference

12 December 2020

Allosteric Effects Govern Nuclear Receptor Action: DNA Appears as a Player

1 reference

12 December 2020

The origin of allosteric functional modulation: multiple pre-existing pathways

1 reference

12 December 2020

'7TM receptor allostery: putting numbers to shapeshifting proteins

1 reference

12 December 2020

The mechanism of ubiquitination in the cullin-RING E3 ligase machinery: conformational control of substrate orientation

1 reference

12 December 2020

The role of dynamic conformational ensembles in biomolecular recognition

1 reference

12 December 2020

Constructing the equilibrium ensemble of folding pathways from short off-equilibrium simulations.

1 reference

12 December 2020

How do transcription factors select specific binding sites in the genome?

1 reference

12 December 2020

During transitions proteins make fleeting bonds.

1 reference

12 December 2020

Transient non-native hydrogen bonds promote activation of a signaling protein

1 reference

12 December 2020

Mechanisms of transcription factor selectivity

1 reference

12 December 2020

Molecular dynamics reveal the essential role of linker motions in the function of cullin-RING E3 ligases

1 reference

12 December 2020

Why does binding of proteins to DNA or proteins to proteins not necessarily spell function?

1 reference

12 December 2020

Restriction of receptor movement alters cellular response: physical force sensing by EphA2.

1 reference

12 December 2020

Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery

1 reference

12 December 2020

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

1 reference

12 December 2020

Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation

1 reference

12 December 2020

Enzyme dynamics point to stepwise conformational selection in catalysis

1 reference

12 December 2020

A mechanistic view of the role of E3 in sumoylation

1 reference

12 December 2020

Allostery and population shift in drug discovery

1 reference

12 December 2020

Protein dynamics and allostery: an NMR view

1 reference

12 December 2020

Alternative allosteric mechanisms can regulate the substrate and E2 in SUMO conjugation

1 reference

12 December 2020

Mapping allostery through the covariance analysis of NMR chemical shifts

1 reference

12 December 2020

Dynamic protein–DNA recognition: beyond what can be seen

1 reference

12 December 2020

Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease

1 reference

12 December 2020

Dynamic allostery: linkers are not merely flexible

1 reference

12 December 2020

How do dynamic cellular signals travel long distances?

1 reference

12 December 2020

Phosphorylation barcoding as a mechanism of directing GPCR signaling

1 reference

12 December 2020

Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.

1 reference

12 December 2020

Gene-specific transcription activation via long-range allosteric shape-shifting

1 reference

12 December 2020

Allo-network drugs: harnessing allostery in cellular networks

1 reference

12 December 2020

Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members

1 reference

12 December 2020

Change in allosteric network affects binding affinities of PDZ domains: analysis through perturbation response scanning

1 reference

12 December 2020

High-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networks

1 reference

12 December 2020

Computational modeling of allosteric communication reveals organizing principles of mutation-induced signaling in ABL and EGFR kinases

1 reference

12 December 2020

Atomistic kinetic model for population shift and allostery in biomolecules

1 reference

12 December 2020

Basic residues in the T-cell receptor ζ cytoplasmic domain mediate membrane association and modulate signaling

1 reference

12 December 2020

Allosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra-molecular communication pathways

1 reference

12 December 2020

Regulation of protein kinases by lipids

1 reference

12 December 2020

NMR insights into protein allostery

1 reference

12 December 2020

The amino-terminal helix modulates light-activated conformational changes in AsLOV2.

1 reference

12 December 2020

Conformational control of the binding of the transactivation domain of the MLL protein and c-Myb to the KIX domain of CREB

1 reference

12 December 2020

Raf inhibitors target ras spatiotemporal dynamics

1 reference

12 December 2020

Conformational selection and induced changes along the catalytic cycle of Escherichia coli dihydrofolate reductase.

1 reference

12 December 2020

Conformational selection in trypsin-like proteases.

1 reference

12 December 2020

Conformational selection and substrate binding regulate the monomer/dimer equilibrium of the C-terminal domain of Escherichia coli enzyme I.

1 reference

12 December 2020

Peptide binding to the PDZ3 domain by conformational selection

1 reference

12 December 2020

Conformational selection or induced fit? A critical appraisal of the kinetic mechanism

1 reference

12 December 2020

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

1 reference

12 December 2020

Combining conformational sampling and selection to identify the binding mode of zinc-bound amyloid peptides with bifunctional molecules

1 reference

12 December 2020

Local folding and misfolding in the PBX homeodomain from a three-state analysis of CPMG relaxation dispersion NMR data

1 reference

12 December 2020

Allosteric post-translational modification codes

1 reference

12 December 2020

Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection

1 reference

12 December 2020

Rational design of allosteric inhibitors and activators using the population-shift model: in vitro validation and application to an artificial biosensor

1 reference

12 December 2020

Allosteric communication across the native and mutated KIT receptor tyrosine kinase

1 reference

12 December 2020

An ensemble view of thrombin allostery

1 reference

12 December 2020

Formation and domain partitioning of H-ras peptide nanoclusters: effects of peptide concentration and lipid composition

1 reference

12 December 2020

Convergent transmission of RNAi guide-target mismatch information across Argonaute internal allosteric network

1 reference

12 December 2020

Ubiquitin dynamics in complexes reveal molecular recognition mechanisms beyond induced fit and conformational selection

1 reference

12 December 2020

MDA5 assembles into a polar helical filament on dsRNA.

1 reference

12 December 2020

The role of flexibility and conformational selection in the binding promiscuity of PDZ domains

1 reference

12 December 2020

Conformational selection underlies recognition of a molybdoenzyme by its dedicated chaperone

1 reference

12 December 2020

Conformational states of the kinase Lck regulate clustering in early T cell signaling

1 reference

12 December 2020

Investigating Allostery in Molecular Recognition: Insights from a Computational Study of Multiple Antibody–Antigen Complexes

1 reference

12 December 2020

A broad view of scaffolding suggests that scaffolding proteins can actively control regulation and signaling of multienzyme complexes through allostery

1 reference

12 December 2020

U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs

1 reference

12 December 2020

Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism

1 reference

12 December 2020

Directional selection precedes conformational selection in ubiquitin-UIM binding.

1 reference

12 December 2020

The underappreciated role of allostery in the cellular network.

1 reference

12 December 2020

Global conformational selection and local induced fit for the recognition between intrinsic disordered p53 and CBP

1 reference

12 December 2020

Conformational selection of translation initiation factor 3 signals proper substrate selection

1 reference

12 December 2020

Eph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiation

1 reference

12 December 2020

Enzymatic detoxication, conformational selection, and the role of molten globule active sites

1 reference

12 December 2020

"Gate-keeper" residues and active-site rearrangements in DNA polymerase μ help discriminate non-cognate nucleotides

1 reference

12 December 2020

The spatial structure of cell signaling systems

1 reference

12 December 2020

Allosteric conformational barcodes direct signaling in the cell

1 reference

12 December 2020

Conformational isomerism and the diversity of antibodies

1 reference

12 December 2020

Protein-protein interfaces: architectures and interactions in protein-protein interfaces and in protein cores. Their similarities and differences

1 reference

12 December 2020

Protein folding via binding and vice versa

1 reference

12 December 2020

10.1016/J.BPC.2013.10.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json

13 May 2020

PubMed publication ID

24239303

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6361548&resulttype=core&format=json