Genetics and personalized medicine--a role in statin therapy? (Q38167710)

30 August 2017

title

Genetics and personalized medicine--a role in statin therapy? (English)

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30 August 2017

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personalized medicine

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24293347%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24293347%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Roger S Blumenthal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24293347%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Thura Abd

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24293347%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Khurram Nasir

series ordinal

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9 June 2020

publication date

1 January 2014

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Current Atherosclerosis Reports

30 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24293347%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

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9 June 2020

issue

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9 June 2020

page(s)

384

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24293347%20AND%20SRC:MED&resulttype=core&format=json

Lipid management to reduce cardiovascular risk: a new strategy is required

9 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: two meta-analyses and a meta-regression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

21 January 2018

Statins personalized.

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Clinical implications of pharmacogenomics of statin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Phenotypic predictors of response to simvastatin therapy among African-Americans and Caucasians: the Cholesterol and Pharmacogenetics (CAP) Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Pharmacogenomics of cholesterol-lowering therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Genomics of Cardiovascular Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Candidate gene identification approach: progress and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

A common allele on chromosome 9 associated with coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

A common variant on chromosome 9p21 affects the risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Genes and coronary artery disease: where are we?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

SLCO1B1 variants and statin-induced myopathy--a genomewide study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Genome-wide association of lipid-lowering response to statins in combined study populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Identification of genetic variants associated with response to statin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Association of apolipoprotein E genotypes with lipid levels and coronary risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

APOE gene polymorphisms and response to statin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Pharmacogenetic study of statin therapy and cholesterol reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

An association study of 43 SNPs in 16 candidate genes with atorvastatin response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Expression of the familial hypercholesterolemia gene in heterozygotes: mechanism for a dominant disorder in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

KIF6 polymorphism as a predictor of risk of coronary events and of clinical event reduction by statin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Kinesin-like protein 6 (KIF6) polymorphism and the efficacy of rosuvastatin in primary prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

The KIF6Collapse⁎⁎Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

High-density lipoprotein and cardiovascular risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Variation at the cholesteryl ester transfer protein gene in relation to plasma high density lipoproteins cholesterol levels and carotid intima-media thickness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

The safety of statins in clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Statin and statin-fibrate use was significantly associated with increased myositis risk in a managed care population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Statin safety: lessons from new drug applications for marketed statins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

The SLCO1B1*5 genetic variant is associated with statin-induced side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Statins, cardiovascular disease, and drug safety

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Transporter pharmacogenetics and statin toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

In vitro and in vivo drug interactions involving human CYP3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Life-threatening rhabdomyolysis following the interaction of two commonly prescribed medications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Drug-eluting stent restenosis rates?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Association of polymorphism in the cytochrome CYP2D6 and the efficacy and tolerability of simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Apolipoprotein-E polymorphism and response to pravastatin in men with coronary artery disease (REGRESS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

The cholesteryl ester transfer protein Taq1B gene polymorphism predicts clinical benefit of statin therapy in patients with significant coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

A systematic review on pharmacogenetics in cardiovascular disease: is it ready for clinical application?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

The role of vitamin D and SLCO1B1 gene polymorphism in statin-associated myalgias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Common nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with type 2 diabetes: a go-DARTS study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Cerivastatin, genetic variants, and the risk of rhabdomyolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

CYP2D6*4 polymorphism is associated with statin-induced muscle effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Genetic analysis of fluvastatin response and dyslipidemia in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Tolerability of statins is not linked to CYP450 polymorphisms, but reduced CYP2D6 metabolism improves cholesteraemic response to simvastatin and fluvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11883-013-0384-Y

No impact of KIF6 genotype on vascular risk and statin response among 18,348 randomized patients in the heart protection study

21 January 2018

1 reference

12 December 2020

Effects of polymorphisms in apolipoproteins E, A-IV, and H on quantitative traits related to risk for cardiovascular disease

1 reference

12 December 2020

Safety of statins: focus on clinical pharmacokinetics and drug interactions

1 reference

12 December 2020

Heterogeneity at the CETP Gene Locus

1 reference

12 December 2020

Apolipoprotein E polymorphism and atherosclerosis

1 reference

12 December 2020

Apoprotein E polymorphism and coronary artery disease. Increased prevalence of apolipoprotein E-4 in angiographically verified coronary patients

1 reference

12 December 2020

Common and rare gene variants affecting plasma LDL cholesterol

1 reference

12 December 2020

The Role of a Common Variant of the Cholesteryl Ester Transfer Protein Gene in the Progression of Coronary Atherosclerosis

1 reference

12 December 2020

The apolipoprotein epsilon4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction : a substudy of the Scandinavian simvastatin survival study

1 reference

12 December 2020

DNA polymorphism at the locus for human cholesteryl ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein levels

1 reference

12 December 2020

Polymorphisms in the gene coding for cholesteryl ester transfer protein are related to plasma high-density lipoprotein cholesterol and transfer protein activity

1 reference

12 December 2020

Relation of polymorphisms in the cholesteryl ester transfer protein gene to transfer protein activity and plasma lipoprotein levels in alcohol drinkers

1 reference

12 December 2020

Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: the Framingham study

1 reference

12 December 2020

10.1007/S11883-013-0384-Y

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24293347%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

1031701322

0 references

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24293347%20AND%20SRC:MED&resulttype=core&format=json