Animal models of scleroderma: current state and recent development (Q38154834)

29 August 2017

title

Animal models of scleroderma: current state and recent development (English)

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29 August 2017

Yoshihide Asano

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29 August 2017

Shinichi Sato

series ordinal

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29 August 2017

publication date

1 December 2013

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Current Rheumatology Reports

29 August 2017

published in

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29 August 2017

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29 August 2017

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29 August 2017

page(s)

382

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Animal model of systemic sclerosis

29 August 2017

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21 January 2018

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In perspective: murine models of scleroderma

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Selective oxidation of DNA topoisomerase 1 induces systemic sclerosis in the mouse.

21 January 2018

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Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis

21 January 2018

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Oxidative stress and the pathogenesis of scleroderma: the Murrell's hypothesis revisited

21 January 2018

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Radical oxygen species production induced by advanced oxidation protein products predicts clinical evolution and response to treatment in systemic sclerosis.

21 January 2018

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Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway

21 January 2018

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Serum levels of 8-isoprostane, a marker of oxidative stress, are elevated in patients with systemic sclerosis.

21 January 2018

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Acute and sustained effects of dihydropyridine-type calcium channel antagonists on oxidative stress in systemic sclerosis

21 January 2018

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Scleroderma autoantigens are uniquely fragmented by metal-catalyzed oxidation reactions: implications for pathogenesis

21 January 2018

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Antinuclear antibody in systemic sclerosis (scleroderma).

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Clinical correlations and prognosis based on serum autoantibodies in patients with systemic sclerosis

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Clinical associations of anticentromere antibodies and antibodies to topoisomerase I. A study of 355 patients

21 January 2018

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CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.

21 January 2018

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Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis

21 January 2018

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Interleukin-1, Interleukin-2, Interleukin-4, Interleukin-6, Tumor Necrosis Factor α, and Interferon-γ Levels in Sera from Patients With Scleroderma

21 January 2018

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The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab.

21 January 2018

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Angiotensin II and renal fibrosis.

21 January 2018

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TGF-beta1 and angiotensin networking in cardiac remodeling

21 January 2018

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Transforming growth factor-beta and angiotensin in fibrosis and burn injuries

21 January 2018

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Angiotensin II and Cardiac Fibrosis

21 January 2018

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Renin-angiotensin system in the pathogenesis of liver fibrosis

21 January 2018

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Angiotensin-converting enzyme 2 in lung diseases

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Demonstration of autoimmunity in the tight skin-2 mouse: a model for scleroderma.

21 January 2018

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An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma

21 January 2018

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Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.

21 January 2018

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Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways.

21 January 2018

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Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma

21 January 2018

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Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice

21 January 2018

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Transforming growth factor-beta in systemic sclerosis (scleroderma).

21 January 2018

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Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1.

21 January 2018

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The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis.

21 January 2018

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Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus

21 January 2018

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Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

21 January 2018

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Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

21 January 2018

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Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors

21 January 2018

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Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia

21 January 2018

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Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor

21 January 2018

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Regulation of Fli1 gene expression and lupus

21 January 2018

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An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes

21 January 2018

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Alpha2(I) collagen gene regulation by protein kinase C signaling in human dermal fibroblasts

21 January 2018

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Persistent down-regulation of Fli1, a suppressor of collagen transcription, in fibrotic scleroderma skin

21 January 2018

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Platelet derived growth factor induced tenascin-C transcription is phosphoinositide 3-kinase/Akt-dependent and mediated by Ets family transcription factors

21 January 2018

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Ets transcription factors cooperate with Sp1 to activate the human tenascin-C promoter

21 January 2018

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Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets1 and Fli1

21 January 2018

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A possible contribution of altered cathepsin B expression to the development of skin sclerosis and vasculopathy in systemic sclerosis

21 January 2018

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Decreased cathepsin V expression due to Fli1 deficiency contributes to the development of dermal fibrosis and proliferative vasculopathy in systemic sclerosis

21 January 2018

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Fli1 and Ets1 have distinct roles in connective tissue growth factor/CCN2 gene regulation and induction of the profibrotic gene program

21 January 2018

1 reference

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Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylation

21 January 2018

1 reference

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Phosphorylation of Fli1 at threonine 312 by protein kinase C delta promotes its interaction with p300/CREB-binding protein-associated factor and subsequent acetylation in response to transforming growth factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0382-7

Transcription factor Fli1 regulates collagen fibrillogenesis in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0382-7

Collagen in the cellular and fibrotic stages of scleroderma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0382-7

Ultrastructural changes induced in cutaneous collagen by ultraviolet-A1 and psoralen plus ultraviolet A therapy in systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0382-7

Fli1 acts at the top of the transcriptional network driving blood and endothelial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0382-7

Endothelial Fli1 deficiency impairs vascular homeostasis: a role in scleroderma vasculopathy.

21 January 2018

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Therapeutic inhibition of tyrosine kinases in systemic sclerosis: a review of published experience on the first 108 patients treated with imatinib

21 January 2018

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The c-Abl tyrosine kinase controls protein kinase Cδ-induced Fli-1 phosphorylation in human dermal fibroblasts

21 January 2018

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Collagen Fibrils of the Scleroderma in Ultra-thin Skin Sections

21 January 2018

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The tight skin 2 mouse. An animal model of scleroderma displaying cutaneous fibrosis and mononuclear cell infiltration

21 January 2018

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12 December 2020

Fli-1 Inhibits Collagen Type I Production in Dermal Fibroblasts via an Sp1-dependent Pathway

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12 December 2020

The emerging problem of oxidative stress and the role of antioxidants in systemic sclerosis

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12 December 2020

Longitudinal analysis of serum cytokine concentrations in systemic sclerosis: association of interleukin 12 elevation with spontaneous regression of skin sclerosis.

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12 December 2020

Oxidative stress in Systemic Sclerosis

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12 December 2020

Anti-topoisomerase I antibodies in silica-associated systemic sclerosis. A model for autoimmunity

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12 December 2020

Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts

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12 December 2020

Longitudinal analysis of autoantibody response to topoisomerase I in systemic sclerosis

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12 December 2020

Scleroderma (systemic sclerosis): classification, subsets and pathogenesis

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12 December 2020

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation

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12 December 2020

Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis

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12 December 2020

Clinical and prognostic associations based on serum antinuclear antibodies in Japanese patients with systemic sclerosis

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12 December 2020

Analysis of the tight skin (Tsk1/+) mouse as a model for testing antifibrotic agents

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12 December 2020

The ultrastructure of collagen in the dermis of tight-skin (Tsk) mutant mice

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12 December 2020

Immunization with DNA topoisomerase I and Freund's complete adjuvant induces skin and lung fibrosis and autoimmunity via interleukin-6 signaling

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12 December 2020

Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology

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12 December 2020

Catalase restores the altered mRNA expression of collagen and matrix metalloproteinases by dermal fibroblasts exposed to reactive oxygen species

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12 December 2020

Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis

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12 December 2020

Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors

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12 December 2020

Alteration of Subcutaneous Tissue in Systemic Scleroderma

1 reference

12 December 2020

10.1007/S11926-013-0382-7

Identifiers

DOI

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Dimensions Publication ID

29 August 2017

1035442756

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