The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis (Q38137731)

29 August 2017

title

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis (English)

1 reference

Mycobacterium tuberculosis

29 August 2017

main subject

0 references

1 reference

29 August 2017

1 reference

29 August 2017

Claudia Binda

0 references

Maria Rosalia Pasca

0 references

Giovanna Riccardi

0 references

Giulia Manina

1 reference

29 August 2017

language of work or name

English

0 references

publication date

14 September 2013

1 reference

Applied Microbiology and Biotechnology

29 August 2017

published in

1 reference

29 August 2017

1 reference

29 August 2017

1 reference

29 August 2017

page(s)

8841-8848

1 reference

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Infectious disease. Approval of novel TB drug celebrated--with restraint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

New tuberculosis drugs on the horizon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Decaprenylphosphoryl-β-D-ribose 2'-epimerase, the target of benzothiazinones and dinitrobenzamides, is an essential enzyme in Mycobacterium smegmatis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Prospects for Tuberculosis Elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Antimycobacterial drugs currently in Phase II clinical trials and preclinical phase for tuberculosis treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Mycobacterium tuberculosis transmission in a country with low tuberculosis incidence: role of immigration and HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Structural analysis of the catalytic mechanism and stereoselectivity in Streptomyces coelicolor alditol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

In vitro combination studies of benzothiazinone lead compound BTZ043 against Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Crystal structure of decaprenylphosphoryl-β-D-ribose 2'-epimerase fromMycobacterium smegmatis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Leads for antitubercular compounds from kinase inhibitor library screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Decaprenylphosphoryl arabinofuranose, the donor of the D-arabinofuranosyl residues of mycobacterial arabinan, is formed via a two-step epimerization of decaprenylphosphoryl ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Clinical isolates of Mycobacterium tuberculosis in four European hospitals are uniformly susceptible to benzothiazinones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Tuberculosis and HIV co-infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Drugs for bad bugs: confronting the challenges of antibacterial discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Exposure of mycobacteria to cell wall-inhibitory drugs decreases production of arabinoglycerolipid related to Mycolyl-arabinogalactan-peptidoglycan metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Modification of the NADH of the Isoniazid Target (InhA) from Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Genes required for mycobacterial growth defined by high density mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Carbon flux rerouting during Mycobacterium tuberculosis growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Thiolates chemically induce redox activation of BTZ043 and related potent nitroaromatic anti-tuberculosis agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

MDR-TB has new drug foe after fast-track approval

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Translating basic science insight into public health action for multidrug- and extensively drug-resistant tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

Advances in the development of new tuberculosis drugs and treatment regimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-5218-X

10.1007/S00253-013-5218-X

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

29 August 2017

1050455851

0 references

1 reference