Genetic regulation and potentially therapeutic application of cancer-associated fibroblasts in oral cancer. (Q38115617)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782231%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Genetic regulation and potentially therapeutic application of cancer-associated fibroblasts in oral cancer (English)

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cancer-associated fibroblast

3 March 2020

main subject

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based on heuristic

inferred from title

lip and oral cavity carcinoma

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3 March 2020

Anjie Min

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3 March 2020

Shan Gao

series ordinal

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3 March 2020

Zhangui Tang

series ordinal

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3 March 2020

publication date

19 June 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782231%20AND%20SRC:MED&resulttype=core&format=json

Journal of Oral Pathology & Medicine

3 March 2020

published in

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3 March 2020

volume

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issue

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3 March 2020

page(s)

323-334

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Genomics and proteomics approaches to the study of cancer-stroma interactions

3 March 2020

cites work

1 reference

21 January 2018

Fibroblasts in cancer

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Origin of carcinoma associated fibroblasts

21 January 2018

1 reference

Cancer-associated fibroblasts and tumor growth--bystanders turning into key players

21 January 2018

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Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness.

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Stromal fibroblasts in cancer initiation and progression

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Cancer-associated stromal fibroblasts promote pancreatic tumor progression

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Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion

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Endothelin-1 stimulates oral fibroblasts to promote oral cancer invasion.

21 January 2018

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Tumor cell and carcinoma-associated fibroblast interaction regulates matrix metalloproteinases and their inhibitors in oral squamous cell carcinoma

21 January 2018

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Autocrine IL-1β-TRAF6 signalling promotes squamous cell carcinoma invasion through paracrine TNFα signalling to carcinoma-associated fibroblasts

21 January 2018

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Snail overexpression induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells

21 January 2018

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Stromal myofibroblasts accompany modifications in the epithelial phenotype of tongue dysplastic and malignant lesions

21 January 2018

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Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction

21 January 2018

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Myofibroblasts and mechano-regulation of connective tissue remodelling

21 January 2018

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CXCR4 and matrix metalloproteinase-1 are elevated in breast carcinoma-associated fibroblasts and in normal mammary fibroblasts exposed to factors secreted by breast cancer cells

21 January 2018

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Identification of stromally expressed molecules in the prostate by tag-profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate

21 January 2018

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Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts

21 January 2018

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The role of endothelial-to-mesenchymal transition in cancer progression

21 January 2018

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LIM-domain proteins in transforming growth factor β-induced epithelial-to-mesenchymal transition and myofibroblast differentiation

21 January 2018

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Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors.

21 January 2018

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The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells

21 January 2018

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Fibroblasts produce brain-derived neurotrophic factor and induce mesenchymal transition of oral tumor cells.

21 January 2018

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Nemosis, a novel way of fibroblast activation, in inflammation and cancer

21 January 2018

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Differences in the nemosis response of normal and cancer-associated fibroblasts from patients with oral squamous cell carcinoma

21 January 2018

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Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

21 January 2018

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Cellular Systems for Studying Human Oral Squamous Cell Carcinomas

21 January 2018

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Influences of tumor stroma on the malignant phenotype

21 January 2018

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Significance of myofibroblasts in oral squamous cell carcinoma

21 January 2018

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Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells

21 January 2018

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A novel organotypic model mimics the tumor microenvironment

21 January 2018

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The hypoxic tumor microenvironment regulates invasion of aggressive oral carcinoma cells.

21 January 2018

1 reference

Species-specific fibroblasts required for triggering invasiveness of partially transformed oral keratinocytes.

21 January 2018

1 reference

Significance of stromal desmoplasia and myofibroblast appearance at the invasive front in squamous cell carcinoma of the oral cavity

21 January 2018

1 reference

Comparison of myofibroblasts expression in oral squamous cell carcinoma, verrucous carcinoma, high risk epithelial dysplasia, low risk epithelial dysplasia and normal oral mucosa.

21 January 2018

1 reference

Regulation of EMT by TGFβ in cancer.

21 January 2018

1 reference

The reactive stroma microenvironment and prostate cancer progression

21 January 2018

1 reference

Inhibition of TGF-β/Smad signaling by BAMBI blocks differentiation of human mesenchymal stem cells to carcinoma-associated fibroblasts and abolishes their protumor effects

21 January 2018

1 reference

Molecular mechanisms of inactivation of TGF-beta receptors during carcinogenesis

21 January 2018

1 reference

Downregulation of TGF-beta receptor types II and III in oral squamous cell carcinoma and oral carcinoma-associated fibroblasts

21 January 2018

1 reference

Upregulation of transforming growth factor-beta1 and vascular endothelial growth factor in cultured keloid fibroblasts: relevance to angiogenic activity

21 January 2018

1 reference

Molecular characterization of the tumor microenvironment in breast cancer

21 January 2018

1 reference

CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex

21 January 2018

1 reference

The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer.

21 January 2018

1 reference

Podoplanin: a novel marker for oral cancer risk in patients with oral premalignancy

21 January 2018

1 reference

Functional invadopodia formation through stabilization of the PDPN transcript by IMP-3 and cancer-stromal crosstalk for PDPN expression.

21 January 2018

1 reference

Recruitment of podoplanin positive cancer-associated fibroblasts in metastatic lymph nodes predicts poor prognosis in pathological N2 stage III lung adenocarcinoma.

21 January 2018

1 reference

Areca-treated fibroblasts enhance tumorigenesis of oral epithelial cells

21 January 2018

1 reference

Corticosteroid co-treatment induces resistance to chemotherapy in surgical resections, xenografts and established cell lines of pancreatic cancer

21 January 2018

1 reference

Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial–mesenchymal transition-like state in breast cancer cells in vitro

21 January 2018

1 reference

Endothelin-1 stimulates motility of head and neck squamous carcinoma cells by promoting stromal-epithelial interactions.

21 January 2018

1 reference

Elevated expression of angiomodulin (AGM/IGFBP-rP1) in tumor stroma and its roles in fibroblast activation

21 January 2018

1 reference

Stromal myofibroblasts are drivers of invasive cancer growth

21 January 2018

1 reference

Tumor-produced, active interleukin-1β regulates gene expression in carcinoma-associated fibroblasts.

21 January 2018

1 reference

Genetic changes in tumour microenvironments

21 January 2018

1 reference

Somatic acquisition of TGFBR1*6A by epithelial and stromal cells during head and neck and colon cancer development

21 January 2018

1 reference

Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas

21 January 2018

1 reference

Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array

21 January 2018

1 reference

Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast

21 January 2018

1 reference

Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer

21 January 2018

1 reference

Gene expressional changes in prostate fibroblasts from cancerous tissue

21 January 2018

1 reference

Combined total genome loss of heterozygosity scan of breast cancer stroma and epithelium reveals multiplicity of stromal targets.

21 January 2018

1 reference

Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation.

21 January 2018

1 reference

Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma

21 January 2018

1 reference

Expression of Snail is associated with myofibroblast phenotype development in oral squamous cell carcinoma

21 January 2018

1 reference

Twist1 is up-regulated in gastric cancer-associated fibroblasts with poor clinical outcomes.

21 January 2018

1 reference

No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

21 January 2018

1 reference

Elegance, silence and nonsense in the mutations literature for solid tumors

21 January 2018

1 reference

Distinct epigenetic changes in the stromal cells of breast cancers

21 January 2018

1 reference

Epigenetic changes in tumor microenvironment

21 January 2018

1 reference

Epigenetic regulation of myofibroblast differentiation by DNA methylation

21 January 2018

1 reference

Targeting microRNAs in cancer: rationale, strategies and challenges

21 January 2018

1 reference

MicroRNAs as potential target gene in cancer gene therapy of gastrointestinal tumors

21 January 2018

1 reference

MicroRNA profiling in cancer

21 January 2018

1 reference

MicroRNAs in an oral cancer context - from basic biology to clinical utility

21 January 2018

1 reference

MicroRNAs: New actors in the oral cancer scene

21 January 2018

1 reference

MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma.

21 January 2018

1 reference

MiRNA expression analysis of cancer-associated fibroblasts and normal fibroblasts in breast cancer.

21 January 2018

1 reference

The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.

21 January 2018

1 reference

A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis

21 January 2018

1 reference

Human natural Treg microRNA signature: role of microRNA-31 and microRNA-21 in FOXP3 expression

21 January 2018

1 reference

Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer

21 January 2018

1 reference

Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression

21 January 2018

1 reference

MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer

21 January 2018

1 reference

Cancer-associated fibroblasts, a parameter of the tumor microenvironment, overcomes carcinoma-associated parameters in the prognosis of patients with mobile tongue cancer

21 January 2018

1 reference

Cancer-associated fibroblasts and epithelial-mesenchymal transition in metastatic oral tongue squamous cell carcinoma

21 January 2018

1 reference

Podoplanin-positive cancer-associated fibroblasts could have prognostic value independent of cancer cell phenotype in stage I lung squamous cell carcinoma: usefulness of combining analysis of both cancer cell phenotype and cancer-associated fibrobla

21 January 2018

1 reference

Stromal PDGFRbeta expression in prostate tumors and non-malignant prostate tissue predicts prostate cancer survival

21 January 2018

1 reference

Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer

21 January 2018

1 reference

Fibroblast activation protein and its relationship to clinical outcome in pancreatic adenocarcinoma

21 January 2018

1 reference

p53 expression in tumor-stromal fibroblasts is closely associated with the nodal metastasis and outcome of patients with invasive ductal carcinoma who received neoadjuvant therapy

21 January 2018

1 reference

Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker

21 January 2018

1 reference

Clinical and functional significance of loss of caveolin-1 expression in breast cancer-associated fibroblasts

21 January 2018

1 reference

Molecular crosstalk between cancer cells and tumor microenvironment components suggests potential targets for new therapeutic approaches in mobile tongue cancer

21 January 2018

1 reference

Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma.

21 January 2018

1 reference

Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting

21 January 2018

1 reference

Selective targeting of interferon γ to stromal fibroblasts and pericytes as a novel therapeutic approach to inhibit angiogenesis and tumor growth.

21 January 2018

1 reference

A novel role of thrombospondin-1 in cervical carcinogenesis: inhibit stroma reaction by inhibiting activated fibroblasts from invading cancer.

21 January 2018

1 reference

Cancer-associated fibroblasts induce matrix metalloproteinase-mediated cetuximab resistance in head and neck squamous cell carcinoma cells

21 January 2018

1 reference

Inhibition of fibroblasts reduced head and neck cancer growth by targeting fibroblast growth factor receptor

21 January 2018

1 reference

Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug

21 January 2018

1 reference

Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

21 January 2018

1 reference

Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model

21 January 2018

1 reference

Toward integrative cancer immunotherapy: targeting the tumor microenvironment

21 January 2018

1 reference

Cancer-associated fibroblasts as targets for immunotherapy

21 January 2018

1 reference

Cancer microenvironment and cancer vaccine

21 January 2018

1 reference

Tumor stroma as targets for cancer therapy

21 January 2018

1 reference

Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neoplastic cell-centric to a stroma-centric paradigm

21 January 2018

1 reference

Breast-Cancer Stromal Cells withTP53Mutations and Nodal Metastases

21 January 2018

1 reference

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/JOP.12098

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782231%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782231%20AND%20SRC:MED&resulttype=core&format=json