Agomelatine, a novel intriguing antidepressant option enhancing neuroplasticity: a critical review (Q38093228)

28 August 2017

title

Agomelatine, a novel intriguing antidepressant option enhancing neuroplasticity: a critical review (English)

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28 August 2017

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Paolo Fusar-Poli

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Marco Innamorati

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Maurizio Pompili

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Paolo Girardi

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28 August 2017

Leo Sher

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28 August 2017

Gianluca Serafini

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28 August 2017

Mario Amore

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28 August 2017

Paola Venturini

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28 August 2017

publication date

26 March 2013

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World Journal of Biological Psychiatry

28 August 2017

published in

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28 August 2017

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28 August 2017

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28 August 2017

page(s)

412-431

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Effect of agomelatine and its interaction with the daily corticosterone rhythm on progenitor cell proliferation in the dentate gyrus of the adult rat.

28 August 2017

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The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling.

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Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data

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Modulation of neuroplastic molecules in selected brain regions after chronic administration of the novel antidepressant agomelatine

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The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats

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The novel antidepressant agomelatine normalizes hippocampal neuronal activity and promotes neurogenesis in chronically stressed rats.

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Chronic stress and antidepressant agomelatine induce region‐specific changes in synapsin I expression in the rat brain

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Neurogenesis in the adult human hippocampus

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A systematic, updated review on the antidepressant agomelatine focusing on its melatonergic modulation

21 January 2018

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Agomelatine prevents relapse in patients with major depressive disorder without evidence of a discontinuation syndrome: a 24-week randomized, double-blind, placebo-controlled trial

21 January 2018

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Melatonin and its new agonist S-20098 restore synchronized sleep fragmented by experimental trypanosome infection in the rat.

21 January 2018

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Is it time to reassess the BDNF hypothesis of depression?

21 January 2018

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Molecular regulation of adult CNS neurogenesis: an integrated view

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Superior antidepressant efficacy results of agomelatine versus fluoxetine in severe MDD patients: a randomized, double-blind study

21 January 2018

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Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain

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Beyond the monoaminergic hypothesis: agomelatine, a new antidepressant with an innovative mechanism of action

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Neurobiological and clinical effects of the antidepressant tianeptine

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Efficacy of the novel antidepressant agomelatine on the circadian rest-activity cycle and depressive and anxiety symptoms in patients with major depressive disorder: a randomized, double-blind comparison with sertraline

21 January 2018

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Placebo-controlled trial of agomelatine in the treatment of major depressive disorder

21 January 2018

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A double-blind comparison of sexual functioning, antidepressant efficacy, and tolerability between agomelatine and venlafaxine XR.

21 January 2018

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Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapies

21 January 2018

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Temporal expression of brain-derived neurotrophic factor (BDNF) mRNA in the rat hippocampus after treatment with selective and mixed monoaminergic antidepressants

21 January 2018

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Improvement in subjective sleep in major depressive disorder with a novel antidepressant, agomelatine: randomized, double-blind comparison with venlafaxine

21 January 2018

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Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT(2C) antagonist, in the treatment of major depressive disorder: a placebo-controlled dose range study

21 January 2018

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21 January 2018

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Neuroplasticity and cellular resilience in mood disorders

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Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression

21 January 2018

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MT(2) melatonin receptors are present and functional in rat caudal artery

21 January 2018

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21 January 2018

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Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration

21 January 2018

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Severe depression and antidepressants: focus on a pooled analysis of placebo-controlled studies on agomelatine

21 January 2018

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Absence of discontinuation symptoms with agomelatine and occurrence of discontinuation symptoms with paroxetine: a randomized, double-blind, placebo-controlled discontinuation study

21 January 2018

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Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats.

21 January 2018

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Expression of membrane and nuclear melatonin receptors in mouse peripheral organs.

21 January 2018

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Neurobiology of depression

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Could agomelatine be the ideal antidepressant?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Effect of agomelatine in the chronic mild stress model of depression in the rat.

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Morphology of pyramidal neurons in the rat prefrontal cortex: lateralized dendritic remodeling by chronic stress

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Hemispheric differences in basilar dendrites and spines of pyramidal neurons in the rat prelimbic cortex: activity- and stress-induced changes

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Stress, depression, and neuroplasticity: a convergence of mechanisms

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Agomelatine in the treatment of seasonal affective disorder

21 January 2018

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Improving adherence in mood disorders: the struggle against relapse, recurrence and suicide risk

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Assessment and treatment of suicide risk in bipolar disorders

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Chronic restraint stress up-regulates GLT-1 mRNA and protein expression in the rat hippocampus: reversal by tianeptine

21 January 2018

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Rhythmic expression of functional MT1 melatonin receptors in the rat adrenal gland

21 January 2018

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Report by the ACNP Task Force on response and remission in major depressive disorder

21 January 2018

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Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat.

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

The expression of MT1 and MT2 melatonin receptor mRNA in several rat tissues

21 January 2018

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Melatonin in the skin: synthesis, metabolism and functions

21 January 2018

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Mechanisms contributing to the phase-dependent regulation of neurogenesis by the novel antidepressant, agomelatine, in the adult rat hippocampus.

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Agomelatine in the treatment of major depressive disorder: an 8-week, multicenter, randomized, placebo-controlled trial

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Comparative effects of a melatonin agonist on the circadian system in mice and Syrian hamsters

21 January 2018

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https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Distribution of MT1 melatonin receptor immunoreactivity in the human hypothalamus and pituitary gland: colocalization of MT1 with vasopressin, oxytocin, and corticotropin-releasing hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Efficacy and safety of agomelatine in the treatment of major depressive disorder: a multicenter, randomized, double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Physiology and pharmacology of melatonin in relation to biological rhythms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Melatonin increases cell proliferation in the dentate gyrus of maternally separated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2013.765593

Antidepressant efficacy of agomelatine versus SSRI/SNRI

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2013.765593

10.3109/15622975.2013.765593

21 January 2018

Identifiers

DOI

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28 August 2017

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