Misfolded proteins recognition strategies of E3 ubiquitin ligases and neurodegenerative diseases (Q38045837)

27 August 2017

title

Misfolded proteins recognition strategies of E3 ubiquitin ligases and neurodegenerative diseases (English)

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27 August 2017

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Deepak Chhangani

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27 August 2017

Nihar Ranjan Jana

series ordinal

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27 August 2017

Amit Mishra

series ordinal

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27 August 2017

publication date

22 September 2012

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27 August 2017

published in

Molecular Neurobiology

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27 August 2017

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27 August 2017

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27 August 2017

page(s)

302-312

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Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

beta-Amyloid-mediated vasoactivity and vascular endothelial damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Protein aggregation as a paradigm of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Interplay between protein homeostasis networks in protein aggregation and proteotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Toxic proteins in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Molecular chaperones in the cytosol: from nascent chain to folded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Cells in stress: transcriptional activation of heat shock genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Protein degradation and protection against misfolded or damaged proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Back to the future with ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The Proteasome: Paradigm of a Self-Compartmentalizing Protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Biological and chemical approaches to diseases of proteostasis deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Protein folding and misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The hunt for huntingtin function: interaction partners tell many different stories

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Transcriptional activation domains of human heat shock factor 1 recruit human SWI/SNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Aggresomes, inclusion bodies and protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Aggresome formation and neurodegenerative diseases: therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Lafora disease in the Indian population: EPM2A and NHLRC1 gene mutations and their impact on subcellular localization of laforin and malin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

How does parkin ligate ubiquitin to Parkinson's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

E3 ubiquitin ligases in protein quality control mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Transcriptional repression and cell death induced by nuclear aggregates of non-polyglutamine protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

UBE3A/E6-AP regulates cell proliferation by promoting proteasomal degradation of p27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Regulation of turnover of tumor suppressor p53 and cell growth by E6-AP, a ubiquitin protein ligase mutated in Angelman mental retardation syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Aggresomes: a cellular response to misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Dynamic association of proteasomal machinery with the centrosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Ataxin-1 poly(Q)-induced proteotoxic stress and apoptosis are attenuated in neural cells by docosahexaenoic acid-derived neuroprotectin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Nuclear protein quality is regulated by the ubiquitin-proteasome system through the activity of Ubc4 and San1 in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

San1-Mediated Quality Control: Substrate Recognition “Sans” Chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Correlating ribosome function with high-resolution structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The native 3D organization of bacterial polysomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

A dual function for chaperones SSB-RAC and the NAC nascent polypeptide-associated complex on ribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Dissecting functional similarities of ribosome-associated chaperones from Saccharomyces cerevisiae and Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Global control of gene expression in yeast by the Ccr4-Not complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Presence of Not5 and ubiquitinated Rps7A in polysome fractions depends upon the Not4 E3 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Quality control of the proteins associated with neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Proteins as molecular chaperones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Involvement of the molecular chaperone Ydj1 in the ubiquitin-dependent degradation of short-lived and abnormal proteins in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The E3 Ligase Smurf1 Regulates Wolfram Syndrome Protein Stability at the Endoplasmic Reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Endoplasmic reticulum stress: cell life and death decisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Endoplasmic reticulum stress-induced cell death mediated by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Ubiquitin ligase Kf-1 is involved in the endoplasmic reticulum-associated degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Cloning of human and mouse cDNAs encoding novel zinc finger proteins expressed in cerebellum and hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The ubiquitin-proteasome system and proteasome inhibitors in central nervous system diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The mouse and human genes encoding the recognition component of the N-end rule pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

A proteolytic pathway that recognizes ubiquitin as a degradation signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

HRD gene dependence of endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Protein aggregation and neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Cell death: protein misfolding and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Quality control against misfolded proteins in the cytosol: a network for cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

UBE3A/E6-AP mutations cause Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Mutations in NHLRC1 cause progressive myoclonus epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Parkin accumulation in aggresomes due to proteasome impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Parkin is recruited to the centrosome in response to inhibition of proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Setting the standards: quality control in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

The role of N-glycans in the secretory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Intracellular functions of N-linked glycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

E3 ubiquitin ligase that recognizes sugar chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoprotein-specific ubiquitin ligase subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Specific Proteins of the Organ of Corti

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8351-0

Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin

21 January 2018

1 reference

12 December 2020

Defective ribosomal products (DRiPs): a major source of antigenic peptides for MHC class I molecules?

1 reference

12 December 2020

Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone Hsc70

1 reference

12 December 2020

Recent studies of the ubiquitin system and the N-end rule pathway

1 reference

12 December 2020

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

1 reference

12 December 2020

Molecular chaperones and the art of recognizing a lost cause

1 reference

12 December 2020

Purification of polyglutamine aggregates and identification of elongation factor-1alpha and heat shock protein 84 as aggregate-interacting proteins.

1 reference

12 December 2020

Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

1 reference

12 December 2020

Regulated protein degradation

1 reference

12 December 2020

The multifunctionality of CHIP protein in the protein quality-control system

1 reference

12 December 2020

10.1007/S12035-012-8351-0

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1024919377

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