What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders (Q38038399)

27 August 2017

title

What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders (English)

1 reference

27 August 2017

C J Westmark

1 reference

27 August 2017

language of work or name

English

0 references

publication date

28 August 2012

1 reference

27 August 2017

1 reference

27 August 2017

1 reference

27 August 2017

1 reference

27 August 2017

page(s)

425-434

1 reference

Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

APP processing in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

FMRP mediates mGluR5-dependent translation of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Molecular mechanisms of fragile X syndrome: a twenty-year perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Beta-amyloid precursor protein isoforms in various rat brain regions and during brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Critical periods during sensory development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Fragile x mental retardation (Fmr-1) gene expression is down regulated in brain of mice during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Intramembrane proteolysis by gamma-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The upside of APP at synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Secreted amyloid precursor protein-alpha upregulates synaptic protein synthesis by a protein kinase G-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Endogenous secreted amyloid precursor protein-alpha regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Secreted form of β-amyloid precursor protein shifts the frequency dependency for induction of LTD, and enhances LTP in hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Biology and pathophysiology of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alzheimer's disease: synapses gone cold

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Mechanism of membrane depolarization caused by the Alzheimer Abeta1-42 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Naturally Secreted Amyloid-β Increases Mammalian Target of Rapamycin (mTOR) Activity via a PRAS40-mediated Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The role of mTOR signaling in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Up-regulation of astrocyte metabotropic glutamate receptor 5 by amyloid-β peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alzheimer Disease in the US Population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Decreased α-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's diseas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

A focus on the synapse for neuroprotection in Alzheimer disease and other dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Soluble beta-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Fragile X: leading the way for targeted treatments in autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Correlates across the structural, functional, and molecular phenotypes of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Gene expression profiles in a transgenic animal model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Adult fragile X syndrome. Clinico-neuropathologic findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Analysis of neocortex in three males with the fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Fragile X-associated tremor/ataxia syndrome (FXTAS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Neuropathological, clinical and molecular pathology in female fragile X premutation carriers with and without FXTAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Successful cognitive aging in rats: a role for mGluR5 glutamate receptors, homer 1 proteins and downstream signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Homer2 and Homer3 interact with amyloid precursor protein and inhibit Abeta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alzheimer's disease in Down's syndrome: clinicopathologic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Plasma β amyloid and the risk of Alzheimer's disease in Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Dendritic anomalies in disorders associated with mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The up-regulation of metabotropic glutamate receptor 5 (mGluR5) in Down's syndrome brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Autism spectrum phenotype in males and females with fragile X full mutation and premutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Understanding and determining the etiology of autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Seizures in elderly patients with dementia: epidemiology and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The Fra(X) syndrome: neurological, electrophysiological, and neuropathological abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Epilepsy and EEG findings in males with fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Seizure Disorders in Down Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Seizure disorders in autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Epilepsy in adolescents and young adults with autistic disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Sodium channel gene family: epilepsy mutations, gene interactions and modifier effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Senile plaques in temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson's disease: the Norwegian ParkWest study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Altered temporal patterns of anxiety in aged and amyloid precursor protein (APP) transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

A perfect storm: Converging paths of epilepsy and Alzheimer’s dementia intersect in the hippocampal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Altered synaptic plasticity in a mouse model of fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

APP processing and synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Increased amyloid beta protein levels in children and adolescents with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Abeta star: a light onto synaptic dysfunction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alzheimer's disease in the retina: imaging retinal aβ plaques for early diagnosis and therapy assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Developing β-secretase inhibitors for treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Beta-secretase inhibitor GRL-8234 rescues age-related cognitive decline in APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

γ-Secretase inhibitors and modulators for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Resolving controversies on the path to Alzheimer's therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Anti-Abeta: The good, the bad, and the unforeseen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alzheimer disease and cerebrovascular pathology: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Cerebral amyloid angiopathy: prospects for clinical diagnosis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Immunotherapy for Alzheimer’s disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Glutamate metabotropic receptors as targets for drug therapy in epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The mGluR theory of fragile X mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Correction of fragile X syndrome in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Prolonged epileptiform discharges induced by altered group I metabotropic glutamate receptor-mediated synaptic responses in hippocampal slices of a fragile X mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Changes in subcellular localization of metabotropic glutamate receptor subtypes during postnatal development of mouse thalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Metabotropic glutamate receptor 5 upregulation in children with autism is associated with underexpression of both Fragile X mental retardation protein and GABAA receptor beta 3 in adults with autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Up-regulation of hippocampal metabotropic glutamate receptor 5 in temporal lobe epilepsy patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Fragile X Syndrome and Alzheimer's Disease: Another story about APP and beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Glycogen synthase kinase-3: a promising therapeutic target for fragile x syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Pathways to drug development for autism spectrum disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

MicroRNAs in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Allele-specific RNAi mitigates phenotypic progression in a transgenic model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

N-methyl-D-aspartate receptors are required for synaptic targeting of Alzheimer's toxic amyloid-β peptide oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Cellular prion protein mediates toxic signaling of amyloid beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Co-stimulation of mGluR5 and N-Methyl-D-aspartate Receptors Is Required for Potentiation of Excitatory Synaptic Transmission in Hippocampal Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Homo- and heterodimerization of APP family members promotes intercellular adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Plasma levels of amyloid beta-protein 42 are increased in women with mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Blood-based neurochemical diagnosis of vascular dementia: a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

An abnormality of plasma amyloid protein precursor in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

High expression on Kunitz-type protease inhibitor-containing substances in the cerebral vessels of patients with Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

A heterogeneous set of FMR1 proteins is widely distributed in mouse tissues and is modulated in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

The regulation of AβPP expression by RNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Regulation of Cell Survival Mechanisms in Alzheimer′s Disease by Glycogen Synthase Kinase‐3

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

β‐Amyloid1–40 Increases Expression of β‐Amyloid Precursor Protein in Neuronal Hybrid Cells

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Amyloid-β-induced amyloid-β secretion: a possible feed-forward mechanism in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Increased neuronal beta-amyloid precursor protein expression in human temporal lobe epilepsy: association with interleukin-1 alpha immunoreactivity

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Plasma beta amyloid level and depression in older adults

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Mutation in codon 713 of the β amyloid precursor protein gene presenting with schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Anticonvulsants attenuate amyloid beta-peptide neurotoxicity, Ca2+ deregulation, and cytoskeletal pathology

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

In vitro characterization of [18F]-florbetaben, an Aβ imaging radiotracer

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Efficient near-infrared in vivo imaging of amyoid-β deposits in Alzheimer's disease mouse models

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Mechanisms of A beta plaque clearance following passive A beta immunization

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Metabotropic glutamate receptors in neurodegeneration/neuroprotection: still a hot topic?

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Increased Soluble APPα, Abeta 1-42, and Anti-Abeta 1-42 Antibodies in Plasma From Down Syndrome Patients

1 reference

https://api.crossref.org/works/10.1038%2FMP.2012.122

7 January 2021

Identifiers

DOI

10.1038/MP.2012.122

1 reference

27 August 2017

1 reference