NADPH oxidases as therapeutic targets in ischemic stroke. (Q38012354)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22618244%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

NADPH oxidases as therapeutic targets in ischemic stroke (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22618244%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22618244%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Timo Kahles

1 reference

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2 February 2020

publication date

23 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22618244%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

2 February 2020

published in

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2 February 2020

volume

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2 February 2020

issue

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2 February 2020

page(s)

2345-2363

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22618244%20AND%20SRC:MED&resulttype=core&format=json

Heart disease and stroke statistics--2011 update: a report from the American Heart Association

2 February 2020

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Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion

21 January 2018

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NADPH oxidase is involved in post-ischemic brain inflammation

21 January 2018

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Mechanisms contributing to cerebral infarct size after stroke: gender, reperfusion, T lymphocytes, and Nox2-derived superoxide

21 January 2018

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Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice.

21 January 2018

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Glucose and NADPH oxidase drive neuronal superoxide formation in stroke.

21 January 2018

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Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke

21 January 2018

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Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.

21 January 2018

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NADPH oxidase inhibitors: new antihypertensive agents?

21 January 2018

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Apocynin improves outcome in experimental stroke with a narrow dose range

21 January 2018

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NOX2 inhibition with apocynin worsens stroke outcome in aged rats

21 January 2018

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NF-kappaB activation plays a role in superoxide-mediated cerebral endothelial dysfunction after hypoxia/reoxygenation

21 January 2018

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Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

21 January 2018

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Atorvastatin protects against cerebral infarction via inhibition of NADPH oxidase-derived superoxide in ischemic stroke

21 January 2018

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Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice

21 January 2018

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Withdrawal of statin treatment abrogates stroke protection in mice

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Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury

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21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Molecular basis for proline- and arginine-rich peptide inhibition of proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Update on endovascular therapies for cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

A peroxisome proliferator-activated receptor-gamma agonist reduces infarct size in transient but not in permanent ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Neuroprotective effects of pioglitazone in a rat model of permanent focal cerebral ischemia are associated with peroxisome proliferator-activated receptor gamma-mediated suppression of nuclear factor-κB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

The role of peroxisome proliferator-activated receptor γ, and effects of its agonist, rosiglitazone, on transient cerebral ischemic damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

PPAR(gamma) agonist rosiglitazone improves vascular function and lowers blood pressure in hypertensive transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Pioglitazone exerts protective effects against stroke in stroke-prone spontaneously hypertensive rats, independently of blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Rosiglitazone reduces glucose-induced oxidative stress mediated by NAD(P)H oxidase via AMPK-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Celastrol: a new therapeutic potential of traditional Chinese medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

The role of protein kinase C in cerebral ischemic and reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

NADPH oxidases in the vasculature: molecular features, roles in disease and pharmacological inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Effects of normobaric hyperoxia in a rat model of focal cerebral ischemia-reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Electron paramagnetic resonance-guided normobaric hyperoxia treatment protects the brain by maintaining penumbral oxygenation in a rat model of transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Inhibition of gp91(phox) contributes towards normobaric hyperoxia afforded neuroprotection in focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Combination effects of normobaric hyperoxia and edaravone on focal cerebral ischemia-induced neuronal damage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Brain oxygen tension, oxygen supply, and oxygen consumption during arterial hyperoxia in a model of progressive cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Ischemic postconditioning inhibits apoptosis after focal cerebral ischemia/reperfusion injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

The Akt signaling pathway contributes to postconditioning's protection against stroke; the protection is associated with the MAPK and PKC pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

After four hours of cold ischemia and cardioplegic protocol, the heart can still be rescued with postconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Interrupted reperfusion reduces the activation of NADPH oxidase after cerebral I/R injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Targeting cerebrovascular Rho-kinase in stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1011-8

Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2

21 January 2018

1 reference

12 December 2020

Oxygen radicals in cerebral ischemia

1 reference

12 December 2020

NOX1 Deficiency Protects From Aortic Dissection in Response to Angiotensin II

1 reference

12 December 2020

Effects of hyperoxia on brain tissue oxygen tension in cerebral focal lesions.

1 reference

12 December 2020

Neuronal death and blood-brain barrier breakdown after excitotoxic injury are independent processes

1 reference

12 December 2020

Role of Rac1 GTPase in NADPH Oxidase Activation and Cognitive Impairment Following Cerebral Ischemia in the Rat

1 reference

12 December 2020

NOX1, 2, 4, 5: counting out oxidative stress

1 reference

12 December 2020

Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer Norfolk prospective population study

1 reference

12 December 2020

Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene

1 reference

12 December 2020

Brain oxygen tension during hyperoxia in a swine model of cerebral ischaemia.

1 reference

12 December 2020

Phosphatidylinositol-3-kinase gamma plays a central role in blood-brain barrier dysfunction in acute experimental stroke

1 reference

12 December 2020

Anti–Intercellular Adhesion Molecule–1 Antibody Reduces Ischemic Cell Damage After Transient But Not Permanent Middle Cerebral Artery Occlusion in the Wistar Rat

1 reference

12 December 2020

iNOS-derived NO and nox2-derived superoxide confer tolerance to excitotoxic brain injury through peroxynitrite

1 reference

12 December 2020

Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage

1 reference

12 December 2020

Apocynin attenuates cerebral infarction after transient focal ischaemia in rats

1 reference

12 December 2020

Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells

1 reference

12 December 2020

Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases

1 reference

12 December 2020

Role and mechanisms of secondary mitochondrial failure.

1 reference

12 December 2020

Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia

1 reference

12 December 2020

Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries

1 reference

12 December 2020

Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats

1 reference

12 December 2020

Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species

1 reference

12 December 2020

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

1 reference

12 December 2020

Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C

1 reference

12 December 2020

Oxidative Stress and Blood–Brain Barrier Dysfunction Under Particular Consideration of Matrix Metalloproteinases

1 reference

12 December 2020

Inducible nitric oxide synthase gene expression in brain following cerebral ischemia

1 reference

12 December 2020

Anti-ICAM-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in the rat

1 reference

12 December 2020

Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells

1 reference

12 December 2020

NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion

1 reference

12 December 2020

Radiosensitization by celastrol is mediated by modification of antioxidant thiol molecules

1 reference

12 December 2020

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

1 reference

12 December 2020

Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation.

1 reference

12 December 2020