Epigenetics: Concepts and relevance to IBD pathogenesis (Q37992592)

26 August 2017

title

Epigenetics: Concepts and relevance to IBD pathogenesis (English)

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26 August 2017

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Melania Scarpa

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26 August 2017

Eleni Stylianou

series ordinal

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26 August 2017

publication date

8 March 2012

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Inflammatory Bowel Diseases

26 August 2017

published in

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26 August 2017

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26 August 2017

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26 August 2017

page(s)

1982-1996

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Inflammatory bowel disease

26 August 2017

cites work

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The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats

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Epigenetic modifications and human disease

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Molecular Signals of Epigenetic States

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Epigenetics as a unifying principle in the aetiology of complex traits and diseases

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Chromatin structure and the inheritance of epigenetic information

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Operating on chromatin, a colorful language where context matters

21 January 2018

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Histone modification: cause or cog?

21 January 2018

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Chromatin modifications and their function

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Histone variants--ancient wrap artists of the epigenome

21 January 2018

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Multivalent engagement of chromatin modifications by linked binding modules

21 January 2018

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Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

21 January 2018

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High-resolution profiling of histone methylations in the human genome

21 January 2018

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Combinatorial patterns of histone acetylations and methylations in the human genome

21 January 2018

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Functions of site-specific histone acetylation and deacetylation

21 January 2018

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Lysine acetylation: codified crosstalk with other posttranslational modifications

21 January 2018

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Histone acetyltransferases

21 January 2018

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Histone deacetylases as regulators of inflammation and immunity

21 January 2018

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Protein methyltransferases as a target class for drug discovery

21 January 2018

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The SET-domain protein superfamily: protein lysine methyltransferases

21 January 2018

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Histone demethylases in development and disease

21 January 2018

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Histone arginine methylation

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When Signaling Kinases Meet Histones and Histone Modifiers in the Nucleus

21 January 2018

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Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation

21 January 2018

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Histone ubiquitination: triggering gene activity

21 January 2018

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The role of deubiquitinating enzymes in chromatin regulation.

21 January 2018

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Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription.

21 January 2018

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Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

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Transcriptional control of the inflammatory response

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Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications

21 January 2018

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Chromatin remodeling through directional DNA translocation from an internal nucleosomal site

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Revealing histone variant induced changes via quantitative proteomics

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Histones: annotating chromatin

21 January 2018

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Regulation of mammalian DNA methyltransferases: a route to new mechanisms

21 January 2018

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Targeting DNA methylation for epigenetic therapy

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Molecular enzymology of mammalian DNA methyltransferases

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Gene body-specific methylation on the active X chromosome

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Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription.

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

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Non-coding RNAs in human disease

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Physiological and pathological roles for microRNAs in the immune system

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PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

21 January 2018

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Gene-specific control of the TLR-induced inflammatory response

21 January 2018

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Selective transcription in response to an inflammatory stimulus

21 January 2018

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Defining mechanisms that regulate RNA polymerase II transcription in vivo

21 January 2018

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Progression through the RNA polymerase II CTD cycle

21 January 2018

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Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

21 January 2018

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Modifying gene expression programs by altering core promoter chromatin architecture.

21 January 2018

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Regulation of cytokine transcription in the context of chromatin

21 January 2018

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Two waves of nuclear factor kappaB recruitment to target promoters

21 January 2018

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Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes

21 January 2018

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p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment

21 January 2018

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A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling

21 January 2018

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Control of inducible gene expression by signal-dependent transcriptional elongation

21 January 2018

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In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions

21 January 2018

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Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response

21 January 2018

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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

21 January 2018

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Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

21 January 2018

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Endotoxin tolerance: new mechanisms, molecules and clinical significance

21 January 2018

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The NF-kappaB factor RelB and histone H3 lysine methyltransferase G9a directly interact to generate epigenetic silencing in endotoxin tolerance

21 January 2018

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Epigenetic silencing of tumor necrosis factor alpha during endotoxin tolerance

21 January 2018

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Dynamic and selective nucleosome repositioning during endotoxin tolerance

21 January 2018

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Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance

21 January 2018

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Epigenetic control of T-helper-cell differentiation

21 January 2018

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At the crossroads of T helper lineage commitment-Epigenetics points the way.

21 January 2018

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Epigenetic mechanisms of regulation of Foxp3 expression

21 January 2018

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Keeping up NF-kappaB appearances: epigenetic control of immunity or inflammation-triggered epigenetics.

21 January 2018

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Phenotypic plasticity and the epigenetics of human disease

21 January 2018

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The epigenomics of cancer

21 January 2018

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The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

21 January 2018

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

21 January 2018

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Global levels of histone modifications predict prognosis in different cancers

21 January 2018

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Aberrations of EZH2 in cancer

21 January 2018

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Deregulation of H3K27 methylation in cancer

21 January 2018

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Epigenetics and B-cell lymphoma

21 January 2018

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Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

21 January 2018

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BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

21 January 2018

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21 January 2018

miRNAs in human cancer

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Aberrant CpG Island Hypermethylation of Chronic Gastritis, in Relation to Aging, Gender, Intestinal Metaplasia, and Chronic Inflammation

21 January 2018

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Impact of inflammation on epigenetic DNA methylation - a novel risk factor for cardiovascular disease?

21 January 2018

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Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

21 January 2018

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Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma

21 January 2018

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CpG island methylation in precursors of gastrointestinal malignancies

21 January 2018

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Promoter methylation of protease-activated receptor (PAR2) is associated with severe clinical phenotypes of ulcerative colitis (UC).

21 January 2018

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Effect of MDR1 gene promoter methylation in patients with ulcerative colitis

21 January 2018

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MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha

21 January 2018

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A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture

21 January 2018

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Trichostatin A, a histone deacetylase inhibitor, suppresses collagen synthesis and prevents TGF-beta(1)-induced fibrogenesis in skin fibroblasts

21 January 2018

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Phenylbutyrate decreases type I collagen production in human lung fibroblasts

21 January 2018

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Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients

21 January 2018

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Suberoylanilide hydroxamic acid: a potential epigenetic therapeutic agent for lung fibrosis?

21 January 2018

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Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo

21 January 2018

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Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

21 January 2018

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Methylation determines fibroblast activation and fibrogenesis in the kidney

21 January 2018

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Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis

21 January 2018

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Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis

21 January 2018

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Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition

21 January 2018

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Chemical probes for histone-modifying enzymes

21 January 2018

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A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis

21 January 2018

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Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents.

21 January 2018

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Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model

21 January 2018

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Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

21 January 2018

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Histone deacetylase inhibitors in inflammatory disease.

21 January 2018

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Anti-inflammatory Agents: Present and Future

21 January 2018

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Butyrate enema therapy stimulates mucosal repair in experimental colitis in the rat.

21 January 2018

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Topical agents for idiopathic distal colitis and proctitis

21 January 2018

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Cellular differentiation, cytidine analogs and DNA methylation

21 January 2018

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

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Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IBD.22934

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26 August 2017

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