Nitric oxide: role in tumour biology and iNOS/NO-based anticancer therapies (Q37872235)

24 August 2017

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title

Nitric oxide: role in tumour biology and iNOS/NO-based anticancer therapies (English)

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24 August 2017

Simendra Singh

1 reference

24 August 2017

Alok K. Gupta

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21544630

1 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21544630

1 December 2024

publication date

5 May 2011

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full work available at URL

24 August 2017

http://link.springer.com/content/pdf/10.1007/s00280-011-1654-4.pdf

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

http://link.springer.com/article/10.1007/s00280-011-1654-4/fulltext.html

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

http://link.springer.com/content/pdf/10.1007/s00280-011-1654-4

1 December 2024

1 reference

DOI

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Cancer Chemotherapy and Pharmacology

1 December 2024

published in

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24 August 2017

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24 August 2017

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24 August 2017

page(s)

1211-1224

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Nitric oxide synthases in mammals

24 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Biochemistry of mitochondrial nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Synthesis of nitric oxide from L-arginine: a recently discovered pathway induced by cytokines with antitumour and antimicrobial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Requirement for transcription factor IRF-1 in NO synthase induction in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

The immunogenicity of tumor cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

HMGB1 and RAGE in inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Differential effects between amphoterin and advanced glycation end products on colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide synthase activity in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Abnormalities in nitric oxide and its derivatives in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Role of nitric oxide in pancreatic tumour growth: in vivo and in vitro studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Inducible nitric oxide synthase (iNOS) expression may predict distant metastasis in human melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Life history of eNOS: partners and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Tumour maintenance is mediated by eNOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Expression of endothelial nitric oxide synthase correlates with the angiogenic phenotype of and predicts poor prognosis in human gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Endothelial nitric oxide synthase immunoreactivity in early gestation and in trophoblastic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

The regulation and pharmacology of endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Role of eNOS in neovascularization: NO for endothelial progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Control of cytochrome c oxidase activity by nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide regulation of mitochondrial oxygen consumption II: Molecular mechanism and tissue physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Update on mechanism and catalytic regulation in the NO synthases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

The biphasic nature of nitric oxide responses in tumor biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Post-translational modifications induced by nitric oxide (NO): implication in cancer cells apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Inhibition of apoptosis signal-regulating kinase 1 by nitric oxide through a thiol redox mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

S-nitrosylation of thioredoxin mediates activation of apoptosis signal-regulating kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide negatively regulates c-Jun N-terminal kinase/stress-activated protein kinase by means of S-nitrosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Activation of c-Ha-Ras by nitric oxide modulates survival responsiveness in neuronal PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Protein glutathiolation by nitric oxide: an intracellular mechanism regulating redox protein modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Activation of p38 mitogen-activated protein kinase (p38 MAPK), extracellular signal-regulated kinase (ERK) and c-jun N-terminal kinase (JNK) during hypoxia in cerebral cortical nuclei of guinea pig fetus at term: role of nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide-stimulated guanine nucleotide exchange on p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide and thiol redox regulation of Janus kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

nitric oxide triggers the phosphatidylinositol 3-kinase/Akt survival pathway in insulin-producing RINm5F cells by arousing Src to activate insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Role of nitric oxide in carcinogenesis and tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide, N omega-hydroxy-L-arginine and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitrosylation of cytochrome c during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Influence of the nitric oxide donor glyceryl trinitrate on apoptotic pathways in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

S-Nitrosylation of mitochondrial caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Role of S-nitrosylation in apoptosis resistance and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide and ionizing radiation synergistically promote apoptosis and growth inhibition of cancer by activating p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitration of the tumor suppressor protein p53 at tyrosine 327 promotes p53 oligomerization and activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: possible functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Dual actions of nitric oxide on angiogenesis: possible roles of PKC, ERK, and AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide inhibits the transcription repressor Yin-Yang 1 binding activity at the silencer region of the Fas promoter: a pivotal role for nitric oxide in the up-regulation of Fas gene expression in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide disrupts H2O2-dependent activation of nuclear factor kappa B. Role in sensitization of human tumor cells to tumor necrosis factor-alpha -induced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Induction of matrix metalloproteinase gene transcription by nitric oxide and mechanisms of MMP-1 gene induction in human melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Vascular endothelial growth factor C and microvessel density in gastric carcinoma: correlation with clinicopathological factors. Our experience and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Clinicopathological significance of vascular endothelial growth factor-C in breast carcinoma with long-term follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

High microvascular density is correlated with high VEGF, iNOS and COX-2 expression in penetrating growth-type early gastric carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide synthase II suppresses the growth and metastasis of human cancer regardless of its up-regulation of protumor factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide-mediated regulation of hypoxia-induced B16F10 melanoma metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide donor increases the efficiency of cytostatic therapy and retards the development of drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide attenuates resistance to doxorubicin in three-dimensional aggregates of human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide enhancement of melphalan-induced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Randomized phase II trial comparing nitroglycerin plus vinorelbine and cisplatin with vinorelbine and cisplatin alone in previously untreated stage IIIB/IV non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Hypoxia-induced genetic instability--a calculated mechanism underlying tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Accumulation of HIF-1alpha under the influence of nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Exploiting tumour hypoxia in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Bioreductive drugs: from concept to clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Non-nuclear localized human NOSII enhances the bioactivation and toxicity of tirapazamine (SR4233) in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Radiogenic therapy: novel approaches for enhancing tumor radiosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Intrinsic radiosensitivity of human pancreatic tumour cells and the radiosensitising potency of the nitric oxide donor sodium nitroprusside

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Radiosensitization by nitric oxide at low radiation doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

The impact of intracellular generation of nitric oxide on the radiation response of human tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Regulation of HIF-1alpha stability through S-nitrosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Mechanisms of action of the organic nitrates in the treatment of myocardial ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Adenoviral gene transfer of the human inducible nitric oxide synthase gene enhances the radiation response of human colorectal cancer associated with alterations in tumor vascularity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Use of the radiation-inducible WAF1 promoter to drive iNOS gene therapy as a novel anti-cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

The role of nitric oxide in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Effect of Nitric Oxide on the Radio-sensitivity of Tumour Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1654-4

Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Selective expression of inducible nitric oxide synthase in human prostate carcinoma

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Expression of endothelial and inducible nitric oxide synthase in benign and malignant lesions of the breast and measurement of nitric oxide using electron paramagnetic resonance spectroscopy

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Increased levels of circulating endothelial progenitor cells and circulating endothelial nitric oxide synthase in patients with gliomas

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Effects of ATP and bradykinin on endothelial cell Ca2+ homeostasis and formation of cGMP and prostacyclin

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression.

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Alteration of NF-κB p50 DNA Binding Kinetics by S-Nitrosylation

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Activation of the Cardiac Calcium Release Channel (Ryanodine Receptor) by Poly-S-Nitrosylation

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Differential activation of mitogen-activated protein kinases by nitric oxide-related species

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Nitric oxide enhancement of fludarabine cytotoxicity for B-CLL lymphocytes.

1 December 2024

1 reference

https://api.crossref.org/works/10.1007/S00280-011-1654-4

Effect of systemic nitric oxide synthase inhibition on postexercise hypotension in humans

1 December 2024

series ordinal

121

1 reference

DOI

https://api.crossref.org/works/10.1007/S00280-011-1654-4

1 December 2024

Identifiers

DOI

1 reference

24 August 2017

1 reference