Phosphorylation, protein kinases and ADPKD (Q37851645)

24 August 2017

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title

Phosphorylation, protein kinases and ADPKD (English)

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Crossref

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

26 November 2024

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Xiaohong Li

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24 August 2017

language of work or name

English

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publication date

15 March 2011

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full work available at URL

24 August 2017

https://biblio.ugent.be/publication/2129216/file/2133988.pdf

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21392577

https://api.elsevier.com/content/article/PII:S0925443911000500?httpAccept=text/xml

26 November 2024

1 reference

Crossref

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

https://api.elsevier.com/content/article/PII:S0925443911000500?httpAccept=text/plain

26 November 2024

1 reference

Crossref

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Biochimica et Biophysica Acta

26 November 2024

published in

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24 August 2017

volume

1812

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24 August 2017

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24 August 2017

page(s)

1219-1224

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Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): The Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort

24 August 2017

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Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

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PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

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Chromosome 4 localization of a second gene for autosomal dominant polycystic kidney disease

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Role of polycystins in renal tubulogenesis

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Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

26 November 2024

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PKD1 interacts with PKD2 through a probable coiled-coil domain

26 November 2024

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Structural and molecular basis of the assembly of the TRPP2/PKD1 complex

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26 November 2024

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Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

26 November 2024

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The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro

26 November 2024

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Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus

26 November 2024

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Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling

26 November 2024

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Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease

26 November 2024

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Polycystin-1 C-terminal cleavage is modulated by polycystin-2 expression

26 November 2024

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Strong homophilic interactions of the Ig-like domains of polycystin-1, the protein product of an autosomal dominant polycystic kidney disease gene, PKD1

26 November 2024

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Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Mouse models of polycystic kidney disease

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Identification of the major site of in vitro PKA phosphorylation in the polycystin-1 C-terminal cytosolic domain

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Identification of phosphorylation sites in the PKD1-encoded protein C-terminal domain

26 November 2024

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The polycystic kidney disease 1 gene product modulates Wnt signaling

26 November 2024

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Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion

26 November 2024

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Polycystin-1 induces resistance to apoptosis through the phosphatidylinositol 3-kinase/Akt signaling pathway.

26 November 2024

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Polycystin-1 activates the calcineurin/NFAT (nuclear factor of activated T-cells) signaling pathway

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

26 November 2024

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Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment

26 November 2024

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Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis

26 November 2024

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The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway

26 November 2024

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Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

26 November 2024

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Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).

26 November 2024

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Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease

26 November 2024

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Deletion of the TSC2 and PKD1 genes associated with severe infantile polycystic kidney disease--a contiguous gene syndrome

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation

26 November 2024

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A polycystin multiprotein complex constitutes a cholesterol-containing signalling microdomain in human kidney epithelia.

26 November 2024

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Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist

26 November 2024

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[Ca2+]i reduction increases cellular proliferation and apoptosis in vascular smooth muscle cells: relevance to the ADPKD phenotype

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Calcium restores a normal proliferation phenotype in human polycystic kidney disease epithelial cells

26 November 2024

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https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

A role for CFTR in human autosomal dominant polycystic kidney disease

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

The cystic fibrosis transmembrane conductance regulator mediates transepithelial fluid secretion by human autosomal dominant polycystic kidney disease epithelium in vitro

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

The relationship between cell proliferation, Cl- secretion, and renal cyst growth: a study using CFTR inhibitors

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Vasopressin antagonists in polycystic kidney disease

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Increased water intake decreases progression of polycystic kidney disease in the PCK rat

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Characterization of structural features that mediate the tethering of Caenorhabditis elegans protein kinase A to a novel A kinase anchor protein. Insights into the anchoring of PKAI isoforms

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Adiponectin inhibits tissue factor expression and enhances tissue factor pathway inhibitor expression in human endothelial cells

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Cyclic AMP suppresses matrix metalloproteinase-1 expression through inhibition of MAPK and GSK-3beta

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

IL-4-induced AID expression and its relevance to IgA class switch recombination

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Polycystin-2 is an intracellular calcium release channel

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females.

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

An unusual catalytic subunit for the cAMP-dependent protein kinase of Dictyostelium discoideum

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Isolation and characterization of Drosophila cAMP-dependent protein kinase genes.

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Multiple roles for cAMP-dependent protein kinase during Dictyostelium development

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Role of cAMP-dependent protein kinase during growth and early development of Dictyostelium discoideum.

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Integration of signaling networks that regulate Dictyostelium differentiation

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Protein kinase X activates ureteric bud branching morphogenesis in developing mouse metanephric kidney

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Protein kinase-X interacts with Pin-1 and Polycystin-1 during mouse kidney development

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide.

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Functions of WW domains in the nucleus

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

NeW wrinkles for an old domain

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

A role for Pin1 in mammalian germ cell development and spermatogenesis

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Pinning down cell signaling, cancer and Alzheimer's disease

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

PrKX is a novel catalytic subunit of the cAMP-dependent protein kinase regulated by the regulatory subunit type I

26 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBADIS.2011.03.001

26 November 2024

Identifiers

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24 August 2017

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