Metabolic remodelling in human heart failure (Q37849446)

24 August 2017

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title

Metabolic remodelling in human heart failure (English)

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24 August 2017

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Juhani Knuuti

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Helena Tuunanen

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24 August 2017

publication date

3 March 2011

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24 August 2017

published in

Cardiovascular Research

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24 August 2017

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24 August 2017

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24 August 2017

page(s)

251-257

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Guidelines for the diagnosis and treatment of chronic heart failure

24 August 2017

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21 January 2018

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Celiprolol augments the effect of physical exercise on insulin sensitivity and serum lipid levels in chronic heart failure

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Effect of selective and nonselective beta-blockers on resting energy production rate and total body substrate utilization in chronic heart failure

21 January 2018

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Carvedilol does not alter the insulin sensitivity in patients with congestive heart failure

21 January 2018

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Glucose metabolism and left ventricular dysfunction are normalized by insulin and islet transplantation in mild diabetes in the rat.

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Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy

21 January 2018

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The failing heart--an engine out of fuel

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Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure

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Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog.

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Total-body and myocardial substrate oxidation in congestive heart failure.

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Abnormalities of whole body protein turnover, muscle metabolism and levels of metabolic hormones in patients with chronic heart failure

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Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.

21 January 2018

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Regional myocardial blood flow reserve impairment and metabolic changes suggesting myocardial ischemia in patients with idiopathic dilated cardiomyopathy

21 January 2018

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Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation

21 January 2018

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Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure

21 January 2018

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Metabolic gene expression in fetal and failing human heart

21 January 2018

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Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure

21 January 2018

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Characterization of altered myocardial fatty acid metabolism in patients with inherited cardiomyopathy

21 January 2018

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Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

21 January 2018

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Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart

21 January 2018

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Myocardial perfusion reserve and peripheral endothelial function in patients with idiopathic dilated cardiomyopathy

21 January 2018

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Myocardial efficiency during levosimendan infusion in congestive heart failure.

21 January 2018

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Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy

21 January 2018

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Effect of metoprolol on myocardial function and energetics in patients with nonischemic dilated cardiomyopathy: a randomized, double-blind, placebo-controlled study

21 January 2018

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Selective versus nonselective beta-adrenergic receptor blockade in chronic heart failure: differential effects on myocardial energy substrate utilization

21 January 2018

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Effect of carvedilol on microcirculatory and glucose metabolic regulation in patients with congestive heart failure secondary to ischemic cardiomyopathy

21 January 2018

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Influence of insulin and free fatty acids on contractile function in patients with chronically stunned and hibernating myocardium

21 January 2018

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Suppression of circulating free fatty acids with acipimox in chronic heart failure patients changes whole body metabolism but does not affect cardiac function

21 January 2018

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Free fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure

21 January 2018

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Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy

21 January 2018

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Effects of trimetazidine on the contractile response of chronically dysfunctional myocardium to low-dose dobutamine in ischaemic cardiomyopathy

21 January 2018

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Long term cardioprotective action of trimetazidine and potential effect on the inflammatory process in patients with ischaemic dilated cardiomyopathy

21 January 2018

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Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure

21 January 2018

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Glycoprotein IIb/IIIa inhibitors in patients with unstable angina/non-ST–segment elevation myocardial infarction: Appropriate interpretation of the guidelines

21 January 2018

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Effects of trimetazidine on ischemic left ventricular dysfunction in patients with coronary artery disease

21 January 2018

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Trimetazidine improves left ventricular function in diabetic patients with coronary artery disease: a double-blind placebo-controlled study.

21 January 2018

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Trimetazidine improves left ventricular function and quality of life in elderly patients with coronary artery disease

21 January 2018

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Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy

21 January 2018

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A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure

21 January 2018

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Effects of trimetazidine on myocardial perfusion and the contractile response of chronically dysfunctional myocardium in ischemic cardiomyopathy: a 24-month study

21 January 2018

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Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in Type 2 diabetic patients.

21 January 2018

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Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment

21 January 2018

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Multi-centre experience on the use of perhexiline in chronic heart failure and refractory angina: old drug, new hope

21 January 2018

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Effects of perhexiline on myocardial deformation in patients with ischaemic left ventricular dysfunction

21 January 2018

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A double-blind randomized multicentre clinical trial to evaluate the efficacy and safety of two doses of etomoxir in comparison with placebo in patients with moderate congestive heart failure: the ERGO (etomoxir for the recovery of glucose oxidation

21 January 2018

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Body composition and prognosis in chronic systolic heart failure: the obesity paradox

21 January 2018

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Decreased Myocardial Free Fatty Acid Uptake in Patients With Idiopathic Dilated Cardiomyopathy: Evidence of Relationship With Insulin Resistance and Left Ventricular Dysfunction

21 January 2018

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Elevated Levels of 8-iso-Prostaglandin F 2α in Pericardial Fluid of Patients With Heart Failure

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/CVR/CVR052

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24 August 2017

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