DP(2) receptor antagonists in development (Q37771028)

22 August 2017

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title

DP(2) receptor antagonists in development (English)

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22 August 2017

Peter Norman

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22 August 2017

language of work or name

English

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publication date

1 August 2010

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Expert Opinion on Investigational Drugs

22 August 2017

published in

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22 August 2017

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22 August 2017

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22 August 2017

page(s)

947-961

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Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Characterisation of receptors mediating the contractile effects of prostanoids in guinea-pig and human airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Effects of a thromboxane-receptor antagonist, BAY u 3405, on prostaglandin D2- and exercise-induced bronchoconstriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

The effect of BAY u 3405, a thromboxane receptor antagonist, on prostaglandin D2-induced nasal blockage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Antagonists of the prostaglandin D2 receptor CRTH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Discovery and optimization of CRTH2 and DP dual antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Tetrahydroquinoline derivatives as CRTH2 antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Inhibitory effect of the 4-aminotetrahydroquinoline derivatives, selective chemoattractant receptor-homologous molecule expressed on T helper 2 cell antagonists, on eosinophil migration induced by prostaglandin D2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

7-Azaindole-3-acetic acid derivatives: potent and selective CRTh2 receptor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

Prostanoid receptor antagonists: development strategies and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2010.500019

10.1517/13543784.2010.500019

21 January 2018

Identifiers

DOI

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22 August 2017

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