The use of transgenic mouse models in the study of male infertility (Q37763943)

22 August 2017

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title

The use of transgenic mouse models in the study of male infertility (English)

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22 August 2017

Kenneth I Aston

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22 August 2017

Susan Tamowski

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22 August 2017

Douglas T Carrell

series ordinal

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22 August 2017

publication date

1 June 2010

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Systems Biology in Reproductive Medicine

22 August 2017

published in

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22 August 2017

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22 August 2017

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22 August 2017

page(s)

260-273

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Mutation analysis of the X-chromosome linked, testis-specific TAF7L gene in spermatogenic failure.

22 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Aberrant protamine 1/protamine 2 ratios in sperm of infertile human males

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Homozygous methylenetetrahydrofolate reductase C677T mutation and male infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Regulation of metallothionein–thymidine kinase fusion plasmids injected into mouse eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Altered protamine expression and diminished spermatogenesis: what is the link?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Abnormal sperm in mice lacking the Taf7l gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Identification of polymorphisms in the Hrb, GOPC, and Csnk2a2 genes in two men with globozoospermia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Screening the SPO11 and EIF5A2 genes in a population of infertile men.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Sequencing and haplotype analysis of the activator of CREM in the testis (ACT) gene in populations of fertile and infertile males

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

RNAi in mice: a promising approach to decipher gene functions in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Mice deficient for RNA-binding protein brunol1 show reduction of spermatogenesis but are fertile

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Ligand-activated site-specific recombination in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Analysis of the meiotic recombination gene REC8 for sequence variations in a population with severe male factor infertility.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Sequence alterations in the YBX2 gene are associated with male factor infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

A histone H3 methyltransferase controls epigenetic events required for meiotic prophase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Conditional brain-specific knockdown of MAPK using Cre/loxP regulated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Conditional over-expression of estrogen receptor alpha in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

DNA repair gene Ercc1 is essential for normal spermatogenesis and oogenesis and for functional integrity of germ cell DNA in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Novel UBE2B-associated polymorphisms in an azoospermic/oligozoospermic population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

An SNP in protamine 1: a possible genetic cause of male infertility?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Depletion of selenoprotein GPx4 in spermatocytes causes male infertility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Failure of the expression of phospholipid hydroperoxide glutathione peroxidase in the spermatozoa of human infertile males

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Mutations in the protamine locus: association with spermatogenic failure?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Single-nucleotide polymorphisms of the PRDM9 (MEISETZ) gene in patients with nonobstructive azoospermia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

ERCC1 and ERCC2 polymorphisms and risk of idiopathic azoospermia in a Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Targeted manipulation of mammalian genomes using designed zinc finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Azoospermia in mice with targeted disruption of the Brek/Lmtk2 (brain-enriched kinase/lemur tyrosine kinase 2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Infertility in 5,10-methylenetetrahydrofolate reductase (MTHFR)-deficient male mice is partially alleviated by lifetime dietary betaine supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Male sterility and enhanced radiation sensitivity in TLS(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Identification of potentially damaging amino acid substitutions leading to human male infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

The mouse meiotic mutation mei1 disrupts chromosome synapsis with sexually dimorphic consequences for meiotic progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

The biology of infertility: research advances and clinical challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Successful Development and Birth of Mice cultivated in vitro as Early Embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Azoospermia in patients heterozygous for a mutation in SYCP3

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Protamines and male infertility.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

The mouse Spo11 gene is required for meiotic chromosome synapsis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

LMTK2 and PARP-2 gene polymorphism and azoospermia secondary to meiotic arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Polymorphic alleles of the human MEI1 gene are associated with human azoospermia by meiotic arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Functional expression of the cre-lox site-specific recombination system in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

BRCA2 deficiency in mice leads to meiotic impairment and infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Production of chimeras between embryonic stem cells and embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

SYCP3 mutations are uncommon in patients with azoospermia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

The methylenetethrahydrofolate reductase (MTHFR) C677T polymorphism and male infertility in Italy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Novel variants in UBE2B gene and idiopathic male infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Impaired spermatogenic ability of testicular germ cells in mice deficient in the LIM-kinase 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Expression profiles and single-nucleotide polymorphism analysis of human HANP1/H1T2 encoding a histone H1-like protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

High frequency targeting of genes to specific sites in the mammalian genome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Polymorphism of the GRTH/DDX25 gene in normal and infertile Japanese men: a missense mutation associated with loss of GRTH phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

No association of the A260G and A386G DAZL single nucleotide polymorphisms with male infertility in a Caucasian population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Conserved role of nanos proteins in germ cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Initial sequencing and comparative analysis of the mouse genome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Physical characteristics of mouse sperm nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Absence of mouse REC8 cohesin promotes synapsis of sister chromatids in meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Male infertility caused by spermiogenic defects: lessons from gene knockouts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Lack of acrosome formation in mice lacking a Golgi protein, GOPC.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Spermiogenesis deficiency in mice lacking the Trf2 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Mutation screening of the FKBP6 gene and its association study with spermatogenic impairment in idiopathic infertile men.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Targeted disruption of the transition protein 2 gene affects sperm chromatin structure and reduces fertility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

The common variant N372H in BRCA2 gene may be associated with idiopathic male infertility with azoospermia or severe oligozoospermia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Meiotic chromosomes: integrating structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

Non-injection methods for the production of embryonic stem cell-embryo chimaeras

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F19396368.2010.485244

10.3109/19396368.2010.485244

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference