Calcium-activated potassium channels - a therapeutic target for modulating nitric oxide in cardiovascular disease? (Q37766237)

22 August 2017

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title

Calcium-activated potassium channels - a therapeutic target for modulating nitric oxide in cardiovascular disease? (English)

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22 August 2017

main subject

cardiovascular disease

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Thomas Dalsgaard

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22 August 2017

Christel Kroigaard

series ordinal

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22 August 2017

Ulf Simonsen

series ordinal

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22 August 2017

language of work or name

English

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publication date

1 August 2010

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Expert Opinion on Therapeutic Targets

22 August 2017

published in

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22 August 2017

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22 August 2017

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22 August 2017

page(s)

825-837

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Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction

22 August 2017

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Determination of the subunit stoichiometry of a voltage-activated potassium channel

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Small and intermediate conductance Ca(2+)-activated K+ channels confer distinctive patterns of distribution in human tissues and differential cellular localisation in the colon and corpus cavernosum

21 January 2018

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Impaired hyperpolarization in regenerated endothelium after balloon catheter injury

21 January 2018

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Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries.

21 January 2018

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Effects of methyl beta-cyclodextrin on EDHF responses in pig and rat arteries; association between SK(Ca) channels and caveolin-rich domains

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Mechanisms underlying epithelium-dependent relaxation in rat bronchioles: analogy to EDHF-type relaxation in rat pulmonary arteries

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Apamin-sensitive K+ currents mediate arachidonic acid-induced relaxations of rabbit aorta

21 January 2018

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Molecular cloning and characterization of the intermediate-conductance Ca(2+)-activated K(+) channel in vascular smooth muscle: relationship between K(Ca) channel diversity and smooth muscle cell function

21 January 2018

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Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis

21 January 2018

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Caveolin, caveolae, and endothelial cell function

21 January 2018

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Transient receptor potential channels and caveolin-1: good friends in tight spaces

21 January 2018

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Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections

21 January 2018

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Distribution, neuronal colocalization, and 17beta-E2 modulation of small conductance calcium-activated K(+) channel (SK3) mRNA in the guinea pig brain

21 January 2018

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SK3-1C, a dominant-negative suppressor of SKCa and IKCa channels

21 January 2018

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Regulation of surface localization of the small conductance Ca2+-activated potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein kinase

21 January 2018

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Protein kinase CK2 is coassembled with small conductance Ca(2+)-activated K+ channels and regulates channel gating

21 January 2018

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Kinase-dependent regulation of the intermediate conductance, calcium-dependent potassium channel, hIK1.

21 January 2018

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Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells

21 January 2018

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Molecular localization of the inhibitory arachidonic acid binding site to the pore of hIK1

21 January 2018

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Modulators of Small- and Intermediate-Conductance Calcium-Activated Potassium Channels and their Therapeutic Indications

21 January 2018

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Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure

21 January 2018

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Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels

21 January 2018

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Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment

21 January 2018

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Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime)

21 January 2018

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21 January 2018

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21 January 2018

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NS309 restores EDHF-type relaxation in mesenteric small arteries from type 2 diabetic ZDF rats

21 January 2018

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Calcium-activated potassium channels contribute to human skeletal muscle microvascular endothelial dysfunction related to cardiopulmonary bypass

21 January 2018

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Calcium-activated potassium channels contribute to human coronary microvascular dysfunction after cardioplegic arrest.

21 January 2018

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Store-operated calcium channels

21 January 2018

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Gating of TRP channels: a voltage connection?

21 January 2018

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Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells

21 January 2018

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Expression of ryanodine receptor type 3 and TRP channels in endothelial cells: comparison of in situ and cultured human endothelial cells

21 January 2018

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Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice

21 January 2018

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Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo

21 January 2018

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Role of endothelial intermediate conductance KCa channels in cerebral EDHF-mediated dilations

21 January 2018

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Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide.

21 January 2018

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Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells

21 January 2018

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L-Arginine therapy in cardiovascular pathologies: beneficial or dangerous?

21 January 2018

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L-arginine transporters in cardiovascular disease: a novel therapeutic target

21 January 2018

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Bradykinin and ATP stimulate L-arginine uptake and nitric oxide release in vascular endothelial cells

21 January 2018

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Alterations in rat interlobar artery membrane potential and K+ channels in genetic and nongenetic hypertension

21 January 2018

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Large-conductance, calcium-activated potassium channels: structural and functional implications

21 January 2018

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TRPC1 associates with BK(Ca) channel to form a signal complex in vascular smooth muscle cells.

21 January 2018

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BK channel modulators: a comprehensive overview

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Inhibition of vascular calcium-gated chloride currents by blockers of KCa1.1, but not by modulators of KCa2.1 or KCa2.3 channels

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Functional coupling of ryanodine receptors to KCa channels in smooth muscle cells from rat cerebral arteries.

21 January 2018

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Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Modulation of BKCa channel gating by endogenous signaling molecules

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Protein kinases: tuners of the BKCa channel in smooth muscle.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Hydrogen peroxide, potassium currents, and membrane potential in human endothelial cells.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Blunted acetylcholine relaxation and nitric oxide release in arteries from renal hypertensive rats

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

LDLs impair vasomotor function of the coronary microcirculation: role of superoxide anions

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities

21 January 2018

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Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Antioxidant vitamin supplements and cardiovascular disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Selective blockade of the intermediate-conductance Ca2+-activated K+ channel suppresses proliferation of microvascular and macrovascular endothelial cells and angiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Blockage of intermediate-conductance-Ca(2+) -activated K(+) channels inhibits progression of human endometrial cancer.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Identification of SK3 channel as a new mediator of breast cancer cell migration

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Evidence for Involvement of Both IK Ca and SK Ca Channels in Hyperpolarizing Responses of the Rat Middle Cerebral Artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

Spatial separation of endothelial small- and intermediate-conductance calcium-activated potassium channels (K(Ca)) and connexins: possible relationship to vasodilator function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.500616

10.1517/14728222.2010.500616

21 January 2018

Identifiers

DOI

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22 August 2017

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