Genetic dissection of inflammatory bowel disease: unravelling etiology and improving diagnostics. (Q37755229)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20477602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Genetic dissection of inflammatory bowel disease: unravelling etiology and improving diagnostics (English)

1 reference

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inflammatory bowel diseases

2 February 2020

main subject

0 references

1 reference

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2 February 2020

Jimmy K Limdi

1 reference

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2 February 2020

Katherine A Siminovitch

series ordinal

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2 February 2020

publication date

1 November 2005

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Expert Review of Clinical Immunology

2 February 2020

published in

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2 February 2020

volume

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2 February 2020

issue

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2 February 2020

page(s)

609-617

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Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences

2 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Cost of illness of inflammatory bowel disease in the UK: a single centre retrospective study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Inflammatory Bowel Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Clinical patterns of familial inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

The IBD2 locus shows linkage heterogeneity between ulcerative colitis and Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

The molecular classification of the clinical manifestations of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

CARD15 and HLA DRB1 alleles influence susceptibility and disease localization in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

CARD15/NOD2 risk alleles in the development of Crohn's disease in the Australian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Lack of common NOD2 variants in Japanese patients with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

The CARD15 (also known as NOD2) gene in Crohn's disease: are there implications for current clinical practice?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Epidemiology of Crohn's disease and ulcerative colitis in a central Canadian province: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

CARD15 genetic variation in a Quebec population: prevalence, genotype-phenotype relationship, and haplotype structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

A novel NOD2/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Mutations in the NOD2/CARD15 gene in Crohn's disease are associated with ileocecal resection and are a risk factor for reoperation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Plant pathogens and integrated defence responses to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Nods: a family of cytosolic proteins that regulate the host response to pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Recognition of pathogen-associated molecular patterns by TLR family

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Activation of nuclear factor kappa B inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Crohn's disease and the NOD2 gene: a role for paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Functional variants of OCTN cation transporter genes are associated with Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

A risk haplotype in the Solute Carrier Family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Genetic variation in DLG5 is associated with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Association of DLG5 R30Q variant with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Crohn's disease--a permeability disorder of the tight junction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Clustering of increased small intestinal permeability in families with Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

The contribution of HLA genes to IBD susceptibility and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

A population- and family-based study of Canadian families reveals association of HLA DRB1*0103 with colonic involvement in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Factors influencing postoperative recurrence of Crohn's disease in childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Marker antibody expression stratifies Crohn's disease into immunologically homogeneous subgroups with distinct clinical characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Association of antibody responses to microbial antigens and complications of small bowel Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Genotypes and phenotypes in Crohn's disease: do they help in clinical management?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Molecular genetics in gastroenterology: from research success to clinical application?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Card15 and Crohn's disease: healthy homozygous carriers of the 3020insC frameshift mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

The role of pharmacogenomics in the prediction of efficacy of anti-TNF therapy in patients with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

NOD2/CARD15 does not influence response to infliximab in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: an analysis in 534 patients from two multicenter, prospective GCP-level trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F1744666X.1.4.609

21 January 2018

Identifiers

DOI

10.1586/1744666X.1.4.609

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20477602%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20477602%20AND%20SRC:MED&resulttype=core&format=json