Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge (Q37681765)

22 August 2017

Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge (English)

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22 August 2017

1 reference

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14 June 2020

Katalin Karikó

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14 June 2020

Drew Weissman

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14 June 2020

Norbert Pardi

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14 June 2020

Hiromi Muramatsu

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14 June 2020

Barbara L Mui

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14 June 2020

Thomas D Madden

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14 June 2020

Houping Ni

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14 June 2020

Ying K Tam

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14 June 2020

Anthony J Secreto

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14 June 2020

Xiaochuan Shan

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14 June 2020

Fotini Debonera

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14 June 2020

Joshua Glover

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14 June 2020

Yanjie Yi

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14 June 2020

Farida Shaheen

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14 June 2020

Gwenn A Danet-Desnoyers

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14 June 2020

Michael J Hope

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14 June 2020

language of work or name

English

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publication date

2 March 2017

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22 August 2017

Nature Communications

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14 June 2020

volume

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14 June 2020

page(s)

14630

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Creative Commons Attribution 4.0 International

14 June 2020

start time

2 March 2017

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Induction of Broad-Based Immunity and Protective Efficacy by Self-amplifying mRNA Vaccines Encoding Influenza Virus Hemagglutinin

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Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction

23 August 2017

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23 August 2017

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Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism

23 August 2017

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Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection

23 August 2017

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23 August 2017

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23 August 2017

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Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo

23 August 2017

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Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin

23 August 2017

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Antibody-based protection against HIV infection by vectored immunoprophylaxis

23 August 2017

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Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA

23 August 2017

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Broad neutralization coverage of HIV by multiple highly potent antibodies

23 August 2017

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Development trends for human monoclonal antibody therapeutics

23 August 2017

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

23 August 2017

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Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody

23 August 2017

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Lipid-like materials for low-dose, in vivo gene silencing

23 August 2017

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Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability

23 August 2017

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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

23 August 2017

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Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

23 August 2017

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New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma

23 August 2017

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Preventing infectious disease with passive immunization

23 August 2017

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Vector-mediated antibody gene transfer for infectious diseases

23 August 2017

1 reference

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6 September 2017

mRNA transcript therapy

1 reference

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mRNA-based therapeutics--developing a new class of drugs

6 September 2017

1 reference

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Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics

6 September 2017

1 reference

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In vitro transcription of long RNA containing modified nucleosides

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

HIV-1 integrates into resting CD4+ T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults

14 September 2017

1 reference

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Chemically modified RNA activated matrices enhance bone regeneration

28 September 2017

1 reference

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Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

HPLC purification of in vitro transcribed long RNA.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

Erythropoietin gene therapy leads to autoimmune anemia in macaques

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5337964

1 September 2018

Identifiers

DOI

10.1038/NCOMMS14630

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28251988%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 June 2020

ADS bibcode

2017NatCo...814630P

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28251988%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

PubMed publication ID

28251988

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28251988%20AND%20SRC:MED&resulttype=core&format=json