The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling (Q37678190)

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scientific article published on 13 January 2017

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English	The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling	scientific article published on 13 January 2017

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scholarly article

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Europe PubMed Central

PMC publication ID

21 August 2017

The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling (English)

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Europe PubMed Central

PMC publication ID

21 August 2017

1 reference

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author name string

Peng Shang

1

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21 August 2017

Mallika Valapala

2

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21 August 2017

Rhonda Grebe

3

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21 August 2017

Stacey Hose

4

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21 August 2017

Sayan Ghosh

5

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21 August 2017

Imran A Bhutto

6

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21 August 2017

James T Handa

7

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21 August 2017

Gerard A Lutty

8

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21 August 2017

Lixia Lu

9

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21 August 2017

Jun Wan

10

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21 August 2017

Jiang Qian

11

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21 August 2017

Yuri Sergeev

12

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21 August 2017

Rosa Puertollano

13

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21 August 2017

J Samuel Zigler

14

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21 August 2017

Guo-Tong Xu

15

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21 August 2017

Debasish Sinha

16

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21 August 2017

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13 January 2017

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21 August 2017

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Europe PubMed Central

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21 August 2017

16

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Europe PubMed Central

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21 August 2017

2

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Europe PubMed Central

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21 August 2017

349-359

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Europe PubMed Central

PMC publication ID

21 August 2017

Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Perspectives on reticular pseudodrusen in age-related macular degeneration.

1 reference

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23 August 2017

TFEB and TFE3 are novel components of the integrated stress response

1 reference

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23 August 2017

PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer

1 reference

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23 August 2017

Lysosomes: Regulators of autophagy in the retinal pigmented epithelium

1 reference

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23 August 2017

In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11

1 reference

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23 August 2017

Recent developments in the management of dry age-related macular degeneration

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23 August 2017

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

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23 August 2017

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

βA3/A1-crystallin: more than a lens protein

1 reference

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23 August 2017

Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response

1 reference

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23 August 2017

mTOR and lysosome regulation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Role of amino acid transporters in amino acid sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Regulation of luminal acidification by the V-ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Regulation of mTORC1 and its impact on gene expression at a glance

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

1 reference

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23 August 2017

Impaired endolysosomal function disrupts Notch signalling in optic nerve astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

TFEB links autophagy to lysosomal biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

Expression of βA3/A1-crystallin in the developing and adult rat eye.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

The Retinal Pigment Epithelium in Health and Disease

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23 August 2017

Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

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23 August 2017

Role of LRAT on the retinoid isomerase activity and membrane association of Rpe65

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5334531

23 August 2017

The retinal pigment epithelium in visual function

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23 August 2017

Alpha-crystallin

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23 August 2017

Age-related decline in chaperone-mediated autophagy

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23 August 2017

Approaches for detecting lysosomal alkalinization and impaired degradation in fresh and cultured RPE cells: evidence for a role in retinal degenerations

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6 September 2017

Cycloheximide inhibits starvation-induced autophagy through mTORC1 activation

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6 September 2017

p62 is a key regulator of nutrient sensing in the mTORC1 pathway.

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6 September 2017

Proton-assisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation

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14 September 2017

Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4.

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Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability

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Modulation of cathepsin D activity in retinal pigment epithelial cells

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1 September 2018

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

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12 December 2020

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10.1111/ACEL.12561

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Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

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Europe PubMed Central

PMC publication ID

21 August 2017

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