Structural insights into G protein-coupled receptor kinase function. (Q37676935)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24680427%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Structural insights into G protein-coupled receptor kinase function (English)

1 reference

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G protein-coupled receptor

12 March 2020

main subject

0 references

1 reference

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12 March 2020

Kristoff T Homan

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12 March 2020

publication date

26 November 2013

1 reference

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Current Opinion in Cell Biology

12 March 2020

published in

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12 March 2020

volume

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12 March 2020

page(s)

25-31

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Structural and Functional Analysis of G Protein-Coupled Receptor Kinase Inhibition by Paroxetine and a Rationally Designed Analog

12 March 2020

cites work

1 reference

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Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process

23 August 2017

1 reference

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Paroxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial Contractility

23 August 2017

1 reference

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Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication

23 August 2017

1 reference

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Molecular Mechanism for Inhibition of G Protein-Coupled Receptor Kinase 2 by a Selective RNA Aptamer

23 August 2017

1 reference

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Substrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1).

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

The origin and evolution of G protein-coupled receptor kinases

23 August 2017

1 reference

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AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model

23 August 2017

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G protein-coupled receptor kinases: more than just kinases and not only for GPCRs

23 August 2017

1 reference

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Heterotrimeric G protein beta1gamma2 subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane

23 August 2017

1 reference

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

23 August 2017

1 reference

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Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors

23 August 2017

1 reference

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Activation of G Protein-Coupled Receptor Kinase 1 Involves Interactions between Its N-Terminal Region and Its Kinase Domain

23 August 2017

1 reference

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Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs

23 August 2017

1 reference

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Molecular basis for activation of G protein-coupled receptor kinases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Structure and function of regulator of G protein signaling homology domains

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Structure of Human G Protein-Coupled Receptor Kinase 2 in Complex with the Kinase Inhibitor Balanol

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

GRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Protein kinase inhibitors: contributions from structure to clinical compounds

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Pathophysiological roles of G-protein-coupled receptor kinases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

A predicted amphipathic helix mediates plasma membrane localization of GRK5

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

23 August 2017

1 reference

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Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Regulation of G protein-coupled receptor kinases by phospholipids

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-kappaB-dependent hypertrophic gene expression.

6 September 2017

1 reference

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Development of a yeast bioassay to characterize G protein-coupled receptor kinases. Identification of an NH2-terminal region essential for receptor phosphorylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

An RNA molecule that specifically inhibits G-protein-coupled receptor kinase 2 in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Inhibition of the beta-adrenergic receptor kinase by polyanions.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3971390

Rhodopsin kinase: substrate specificity and factors that influence activity

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24680427

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24680427

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CEB.2013.10.009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24680427%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24680427%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24680427

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24680427%20AND%20SRC:MED&resulttype=core&format=json