The Hedgehog signalling pathway as a therapeutic target in early breast cancer development. (Q37573820)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

review article

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title

The Hedgehog signalling pathway as a therapeutic target in early breast cancer development (English)

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4 February 2020

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4 February 2020

Sandra A O'Toole

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4 February 2020

Robert L Sutherland

series ordinal

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4 February 2020

language of work or name

English

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publication date

1 September 2009

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Expert Opinion on Therapeutic Targets

4 February 2020

published in

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4 February 2020

volume

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4 February 2020

issue

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4 February 2020

page(s)

1095-1103

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Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

4 February 2020

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

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Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia

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Sonic Hedgehog as a mediator of long-range signaling

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Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

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Cholesterol modification restricts the spread of Shh gradient in the limb bud.

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A freely diffusible form of Sonic hedgehog mediates long-range signalling

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Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling

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Pathways of signal transduction employed by vertebrate Hedgehogs

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Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation

21 January 2018

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Hedgehog signalling in the mouse requires intraflagellar transport proteins

21 January 2018

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Hedgehog signaling in animal development: paradigms and principles

21 January 2018

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Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.

21 January 2018

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Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells

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Hedgehog drugs begin to show results

21 January 2018

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21 January 2018

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Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: pathological significance in early- and late-onset breast carcinoma

21 January 2018

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21 January 2018

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21 January 2018

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10.1517/14728220903130612

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19659449%20AND%20SRC:MED&resulttype=core&format=json