Targeting CD133 antigen in cancer (Q37521082)

20 August 2017

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title

Targeting CD133 antigen in cancer (English)

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20 August 2017

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Giovanni Scambia

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20 August 2017

Gabriella Ferrandina

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20 August 2017

Marco Petrillo

series ordinal

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20 August 2017

Giuseppina Bonanno

series ordinal

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20 August 2017

language of work or name

English

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publication date

1 July 2009

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Expert Opinion on Therapeutic Targets

20 August 2017

published in

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20 August 2017

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20 August 2017

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20 August 2017

page(s)

823-837

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Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells

20 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

The stem-cell niche as an entity of action

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903005616

Pluripotent human stem cell lines: what we can learn about cancer initiation.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728220903005616

Tumour-initiating cells vs. cancer 'stem' cells and CD133: what's in the name?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Side-population cells from different precursor compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Cancer stem cells: models and concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Exploring the role of cancer stem cells in radioresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Stem cell marker CD133 affects clinical outcome in glioma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Identification and expansion of human colon-cancer-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Expression of CD133-1 and CD133-2 in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Prospective identification of tumorigenic prostate cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

The stem cell-associated antigen CD133 (Prominin-1) is a molecular therapeutic target for metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Nomenclature of prominin-1 (CD133) splice variants - an update.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

AC133-2, a novel isoform of human AC133 stem cell antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Segregation of lipid raft markers including CD133 in polarized human hematopoietic stem and progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Prominin-2 is a cholesterol-binding protein associated with apical and basolateral plasmalemmal protrusions in polarized epithelial cells and released into urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

New insights into the cell biology of hematopoietic progenitors by studying prominin-1 (CD133).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Focus on molecules: prominin-1 (CD133).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

The Hedgehog and Wnt signalling pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

GLI transcription factors: mediators of oncogenic Hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Module map of stem cell genes guides creation of epithelial cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

c-Myc is required for maintenance of glioma cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Cancerous stem cells can arise from pediatric brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

CD133+ renal progenitor cells contribute to tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Identification and expansion of the tumorigenic lung cancer stem cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Increased expression of stem cell markers in malignant melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Identification of CD133-positive radioresistant cells in atypical teratoid/rhabdoid tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Biological and genetic characteristics of tumor-initiating cells in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Tumour stem cells and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Enhanced radiosensitivity and radiation-induced apoptosis in glioma CD133-positive cells by knockdown of SirT1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Medulloblastoma growth inhibition by hedgehog pathway blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Different response of human glioma tumor-initiating cells to epidermal growth factor receptor kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: inhibitors of the Wnt/beta-catenin signaling pathway as novel anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

Expression of MHC I and NK ligands on human CD133+ glioma cells: possible targets of immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903005616

10.1517/14728220903005616

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

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