Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb. (Q37494834)

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scientific article published on 09 January 2012

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English	Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.	scientific article published on 09 January 2012

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20 January 2020

Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb (English)

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20 January 2020

Takeshi Miyazaki

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20 January 2020

Mariano S Viapiano

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20 January 2020

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20 January 2020

Hiroyuki Seimiya

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20 January 2020

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Yang Pan

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20 January 2020

Kaushal Joshi

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20 January 2020

Deepti Purohit

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20 January 2020

Bin Hu

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20 January 2020

Habibe Demir

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20 January 2020

Sarmistha Mazumder

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20 January 2020

Sachiko Okabe

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20 January 2020

Takao Yamori

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20 January 2020

Ichiro Nakano

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20 January 2020

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9 January 2012

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20 January 2020

Clinical Cancer Research

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20 January 2020

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20 January 2020

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20 January 2020

1268-1280

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20 January 2020

A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells

1 reference

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Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway

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Potential therapeutic implications of cancer stem cells in glioblastoma

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Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression

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SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma

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23 August 2017

Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors

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23 August 2017

The proteoglycan brevican binds to fibronectin after proteolytic cleavage and promotes glioma cell motility

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23 August 2017

BEHAB/brevican requires ADAMTS-mediated proteolytic cleavage to promote glioma invasion.

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23 August 2017

Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene

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23 August 2017

Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.

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23 August 2017

Brain tumour stem cells

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23 August 2017

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

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Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation

1 reference

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

1 reference

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Cancerous stem cells can arise from pediatric brain tumors

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Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

1 reference

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Identification of a cancer stem cell in human brain tumors

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DNA damage foci at dysfunctional telomeres

1 reference

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23 August 2017

Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus

1 reference

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Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

1 reference

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23 August 2017

A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity

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Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter

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6 September 2017

Stabilization of the c-myc gene promoter quadruplex by specific ligands' inhibitors of telomerase.

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6 September 2017

Interaction of telomestatin with the telomeric single-strand overhang.

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6 September 2017

Telomerase inhibition and cell growth arrest after telomestatin treatment in multiple myeloma

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Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells

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14 September 2017

G-quadruplexes in promoters throughout the human genome

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G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells

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3 December 2018

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10.1158/1078-0432.CCR-11-1795

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20 January 2020

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20 January 2020

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20 January 2020

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