Metabolic transformation in cancer. (Q37423585)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19321800%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

review article

1 reference

title

Metabolic transformation in cancer (English)

1 reference

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24 January 2020

1 reference

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24 January 2020

1 reference

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24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19321800%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Houda Boulahbel

1 reference

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24 January 2020

language of work or name

English

0 references

publication date

25 March 2009

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24 January 2020

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24 January 2020

volume

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24 January 2020

issue

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24 January 2020

page(s)

1269-1280

1 reference

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Mitochondria in cancer: not just innocent bystanders

24 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

On the Origin of Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The carbohydrate metabolism of certain pathological overgrowths

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Glycolysis in cancer: a potential target for therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Concepts of oxygen transport at the microcirculatory level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Dominant-negative HIF-3 alpha 4 suppresses VHL-null renal cell carcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The role of iron and 2-oxoglutarate oxygenases in signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

PHD2 mutation and congenital erythrocytosis with paraganglioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Overexpression of the oxygen sensors PHD-1, PHD-2, PHD-3, and FIH Is associated with tumor aggressiveness in pancreatic endocrine tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Superoxide flashes in single mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Von Hippel-Lindau disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

c-Myc target genes involved in cell growth, apoptosis, and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Transcriptional regulation and transformation by Myc proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Oncogenes in tumor metabolism, tumorigenesis, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Novel roles of the autocrine motility factor/phosphoglucose isomerase in tumor malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Identification of genes differentially induced by hypoxia in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Regulation of 6-phosphofructo-1-kinase activity in ras-transformed rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Ras transformation requires metabolic control by 6-phosphofructo-2-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Pyruvate kinase type M2 is phosphorylated at tyrosine residues in cells transformed by Rous sarcoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Pyruvate kinase M2 is a phosphotyrosine-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Cancer patients opt for unapproved drug.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

ATP citrate lyase inhibition can suppress tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Molecular mechanisms of glutamine action

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Co-expression of glutaminase K and L isoenzymes in human tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Mitochondrial tumour suppressors: a genetic and biochemical update

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

How mitochondria produce reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

p53 regulates mitochondrial respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Molecular and functional analysis of glutamine uptake in human hepatoma and liver-derived cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Inducible antisense RNA targeting amino acid transporter ATB0/ASCT2 elicits apoptosis in human hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The transport of glutamine into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Regulation of TORC1 by Rag GTPases in nutrient response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Growing roles for the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

TOR signaling in growth and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

ASCT2 silencing regulates mammalian target-of-rapamycin growth and survival signaling in human hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Urinary alpha-ketoglutarate is elevated in patients with hyperinsulinism-hyperammonemia syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Tumorigenic activity and therapeutic inhibition of Rheb GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Defining the role of mTOR in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGP070

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGP070

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19321800%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19321800%20AND%20SRC:MED&resulttype=core&format=json