Preclinical activity of the rational combination of selumetinib (AZD6244) in combination with vorinostat in KRAS-mutant colorectal cancer models. (Q37421431)

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scientific article published on 15 December 2011

Language	Label	Description	Also known as
English	Preclinical activity of the rational combination of selumetinib (AZD6244) in combination with vorinostat in KRAS-mutant colorectal cancer models.	scientific article published on 15 December 2011

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scholarly article

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18 January 2020

Preclinical activity of the rational combination of selumetinib (AZD6244) in combination with vorinostat in KRAS-mutant colorectal cancer models (English)

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18 January 2020

colorectal cancer

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based on heuristic

inferred from title

colorectal carcinoma

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based on heuristic

inferred from title

11

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18 January 2020

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18 January 2020

Fortunato Ciardiello

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18 January 2020

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M Pia Morelli

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18 January 2020

John J Tentler

2

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18 January 2020

Gillian N Kulikowski

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18 January 2020

Erica L Bradshaw-Pierce

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18 January 2020

Todd M Pitts

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18 January 2020

Amy M Brown

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18 January 2020

Sujatha Nallapareddy

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18 January 2020

John J Arcaroli

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18 January 2020

Natalie J Serkova

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18 January 2020

S Gail Eckhardt

13

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18 January 2020

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15 December 2011

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18 January 2020

Clinical Cancer Research

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18 January 2020

18

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18 January 2020

4

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18 January 2020

1051-1062

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18 January 2020

Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer.

1 reference

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23 August 2017

Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244)

1 reference

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KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection

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Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients

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FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma

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23 August 2017

Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes

1 reference

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23 August 2017

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23 August 2017

Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy

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A role for K-ras in conferring resistance to the MEK inhibitor, CI-1040.

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12 December 2020

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inferred from PubMed ID database lookup

HDAC inhibitors in leukemia: current status and perspectives

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1 reference

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12 December 2020

based on heuristic

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10.1158/1078-0432.CCR-11-1507

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18 January 2020

release_tcgo4figybbuhgtasb45hnzjyi

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24 November 2022

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18 January 2020

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18 January 2020

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