The role of Galectin-3/MAC-2 in the activation of the innate-immune function of phagocytosis in microglia in injury and disease (Q37404610)

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scientific article published on 28 February 2009

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English	The role of Galectin-3/MAC-2 in the activation of the innate-immune function of phagocytosis in microglia in injury and disease	scientific article published on 28 February 2009

Statements

instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

19253007

retrieved

20 August 2017

review article

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stated in

Europe PubMed Central

title

The role of Galectin-3/MAC-2 in the activation of the innate-immune function of phagocytosis in microglia in injury and disease (English)

1 reference

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Europe PubMed Central

PubMed publication ID

19253007

retrieved

20 August 2017

main subject

microglia

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phagocytosis

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based on heuristic

inferred from title

immune function

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based on heuristic

inferred from title

author name string

Shlomo Rotshenker

series ordinal

1

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stated in

Europe PubMed Central

PubMed publication ID

19253007

retrieved

20 August 2017

publication date

28 February 2009

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19253007

retrieved

20 August 2017

published in

Journal of Molecular Neuroscience

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stated in

Europe PubMed Central

PubMed publication ID

19253007

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20 August 2017

volume

39

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stated in

Europe PubMed Central

PubMed publication ID

19253007

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20 August 2017

issue

1-2

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stated in

Europe PubMed Central

PubMed publication ID

19253007

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20 August 2017

page(s)

99-103

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Europe PubMed Central

PubMed publication ID

19253007

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20 August 2017

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Easing the brakes on spinal cord repair

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Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

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The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Deficient activation of microglia during optic nerve degeneration

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https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression.

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12 December 2020

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Microglia and Macrophage Activation and the Regulation of Complement-Receptor-3 (CR3/MAC-1)-Mediated Myelin Phagocytosis in Injury and Disease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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The cytokine network of wallerian degeneration: IL-10 and GM-CSF.

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Therapeutic approaches to promoting axonal regeneration in the adult mammalian spinal cord.

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Spatiotemporal organization of Ras signaling: rasosomes and the galectin switch

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The brain as a target for inflammatory processes and neuroprotective strategies

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12 December 2020

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Modulation (inhibition and augmentation) of complement receptor-3-mediated myelin phagocytosis

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12 December 2020

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The Membrane Attack Complex of Complement Causes Severe Demyelination Associated with Acute Axonal Injury

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12 December 2020

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Galectin-3/MAC-2 in experimental allergic encephalomyelitis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Granulocyte macrophage colony stimulating factor produced in lesioned peripheral nerves induces the up-regulation of cell surface expression of MAC-2 by macrophages and Schwann cells

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https://pubmed.ncbi.nlm.nih.gov/19253007

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Galectin-3/MAC-2, Ras and PI3K activate complement receptor-3 and scavenger receptor-AI/II mediated myelin phagocytosis in microglia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

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12 December 2020

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Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Isolation of membrane attack complex of complement from myelin membranes treated with serum complement

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

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Non-PKC DAG/phorbol-ester receptor(s) inhibit complement receptor-3 and nPKC inhibit scavenger receptor-AI/II-mediated myelin phagocytosis but cPKC, PI3k, and PLCgamma activate myelin phagocytosis by both

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

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Peripheral nerve injury induces Schwann cells to express two macrophage phenotypes: phagocytosis and the galactose-specific lectin MAC-2.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Phosphatidylinositol 3-kinase, phosphoinositide-specific phospholipase-Cgamma and protein kinase-C signal myelin phagocytosis mediated by complement receptor-3 alone and combined with scavenger receptor-AI/II in macrophages

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement-receptor-3 and scavenger-receptor-AI/II mediated myelin phagocytosis in microglia and macrophages

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct inflammatory stimuli induce different patterns of myelin phagocytosis and degradation in recruited macrophages.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

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Glial inhibition of CNS axon regeneration

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

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Microglia: a sensor for pathological events in the CNS

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Galectin-3: an open-ended story

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galectins: structure, function and therapeutic potential

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage responses and myelin clearance during Wallerian degeneration: relevance to immune-mediated demyelination

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phagocytic properties of microglia in vitro: implications for a role in multiple sclerosis and EAE.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

based on heuristic

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Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune transferred experimental autoimmune encephalomyelitis: An investigation using rat radiation bone marrow chimeras

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19253007

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12 December 2020

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Identifiers

DOI

10.1007/S12031-009-9186-7

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19253007

retrieved

20 August 2017

PubMed publication ID

19253007

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19253007

retrieved

20 August 2017

ResearchGate publication ID

24147509

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