Cell surface heparan sulfate released by heparanase promotes melanoma cell migration and angiogenesis (Q37330599)

19 August 2017

Cell surface heparan sulfate released by heparanase promotes melanoma cell migration and angiogenesis (English)

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19 August 2017

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1 reference

Madhuchhanda Roy

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19 August 2017

Dario Marchetti

series ordinal

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19 August 2017

1 February 2009

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Journal of Cellular Biochemistry

19 August 2017

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19 August 2017

106

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19 August 2017

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19 August 2017

200-209

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describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2736788/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Mammalian heparanase: what is the message?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

Heparanase: a target for drug discovery in cancer and inflammation

6 September 2017

1 reference

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Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma

6 September 2017

1 reference

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Heparanase localization and expression by head and neck cancer: correlation with tumor progression and patient survival

6 September 2017

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Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis

6 September 2017

1 reference

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FGF2 binding, signaling, and angiogenesis are modulated by heparanase in metastatic melanoma cells

6 September 2017

1 reference

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Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic

6 September 2017

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HSulf-1 inhibits angiogenesis and tumorigenesis in vivo

6 September 2017

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VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase

6 September 2017

1 reference

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HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo

6 September 2017

1 reference

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Enzymatic remodeling of heparan sulfate proteoglycans within the tumor microenvironment: growth regulation and the prospect of new cancer therapies.

6 September 2017

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Antisense-mediated suppression of Heparanase gene inhibits melanoma cell invasion

6 September 2017

1 reference

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The biology of VEGF and its receptors

6 September 2017

1 reference

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Roles of heparan-sulphate glycosaminoglycans in cancer

6 September 2017

1 reference

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Order out of chaos: assembly of ligand binding sites in heparan sulfate

6 September 2017

1 reference

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Dynamic regulation of tumor growth and metastasis by heparan sulfate glycosaminoglycans

6 September 2017

1 reference

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Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis

6 September 2017

1 reference

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Heparan sulfate: growth control with a restricted sequence menu

6 September 2017

1 reference

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Molecular diversity of heparan sulfate

6 September 2017

1 reference

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Heparan sulfate proteoglycans: intricate molecules with intriguing functions.

6 September 2017

1 reference

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Expression of heparanase in normal, dysplastic, and neoplastic human colonic mucosa and stroma. Evidence for its role in colonic tumorigenesis

6 September 2017

1 reference

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Heparanase, a potential regulator of cell-matrix interactions

6 September 2017

1 reference

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Mechanisms of angiogenesis and arteriogenesis

6 September 2017

1 reference

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Cloning and functional expression of a human heparanase gene

6 September 2017

1 reference

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Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

6 September 2017

1 reference

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Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

6 September 2017

1 reference

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Two hierarchies of FGF-2 signaling in heparin: mitogenic stimulation and high-affinity binding/receptor transphosphorylation.

6 September 2017

1 reference

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

6 September 2017

1 reference

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Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

6 September 2017

1 reference

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Tumor angiogenesis: therapeutic implications

6 September 2017

1 reference

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Heparanases and tumor metastasis

6 September 2017

1 reference

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Vascular endothelial growth factor is a secreted angiogenic mitogen

6 September 2017

1 reference

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In vivo and in vitro degradation of heparan sulfate (HS) proteoglycans by HPR1 in pancreatic adenocarcinomas. Loss of cell surface HS suppresses fibroblast growth factor 2-mediated cell signaling and proliferation

6 September 2017

1 reference

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Heparanase, TrkC and p75NTR: their functional involvement in human medulloblastoma cell invasion.

14 September 2017

1 reference

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Heparanase affects adhesive and tumorigenic potential of human glioma cells

14 September 2017

1 reference

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Heparanase and a synthetic peptide of heparan sulfate-interacting protein recognize common sites on cell surface and extracellular matrix heparan sulfate

14 September 2017

1 reference

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Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors?

28 September 2017

1 reference

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Selective binding of VEGF121 to one of the three vascular endothelial growth factor receptors of vascular endothelial cells

28 September 2017

1 reference

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Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

VEGF receptor subtypes KDR and FLT1 show different sensitivities to heparin and placenta growth factor

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

Biochemical characterization of the active heterodimer form of human heparanase (Hpa1) protein expressed in insect cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

Specific degradation of subendothelial matrix proteoglycans by brain-metastatic melanoma and brain endothelial cell heparanases

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2736788

Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis

2 September 2018

1 reference

12 December 2020

Heparanase as mediator of angiogenesis: mode of action

1 reference

12 December 2020

Antisense-mediated suppression of human heparanase gene expression inhibits pleural dissemination of human cancer cells

1 reference

12 December 2020

Human heparanase-1 gene expression in pancreatic adenocarcinoma

1 reference

12 December 2020

Heparanase: a key enzyme in invasion and metastasis of gastric carcinoma

1 reference

12 December 2020

Heparanase-1 expression is associated with the metastatic potential of breast cancer

1 reference

12 December 2020

High heparanase activity in multiple myeloma is associated with elevated microvessel density

1 reference

12 December 2020

Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion

1 reference

12 December 2020

Evidence that sulphated polysaccharides inhibit tumour metastasis by blocking tumour-cell-derived heparanases

1 reference

12 December 2020

Preparation and structural characterization of large heparin-derived oligosaccharides

1 reference

12 December 2020

Involvement of neurotrophins and growth factors in brain metastasis formation

1 reference

12 December 2020

Identifiers

DOI

10.1002/JCB.22005

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

19115257

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