Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: a randomized controlled trial (Q37289596)

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scientific article published on July 2012

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English	Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: a randomized controlled trial	scientific article published on July 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: a randomized controlled trial (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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anti-retroviral agent

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hydroxychloroquine

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object named as

Samuel Franzen

4

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Ruth L. Goodall

object named as

Ruth L Goodall

2

0 references

11

object named as

Chloe Orkin

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Mark Wansbrough-Jones

15

object named as

Mark Wansbrough-Jones

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Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Nicholas I Paton

1

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19 August 2017

David T Dunn

3

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Europe PubMed Central

PMC publication ID

19 August 2017

Yolanda Collaco-Moraes

5

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Europe PubMed Central

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19 August 2017

Brian G Gazzard

6

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Europe PubMed Central

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19 August 2017

Ian G Williams

7

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Europe PubMed Central

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19 August 2017

Martin J Fisher

8

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Europe PubMed Central

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19 August 2017

Alan Winston

9

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Europe PubMed Central

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19 August 2017

Julie Fox

10

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Europe PubMed Central

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19 August 2017

Elbushra A Herieka

12

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Europe PubMed Central

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19 August 2017

Jonathan G Ainsworth

13

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Europe PubMed Central

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19 August 2017

Frank A Post

14

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Europe PubMed Central

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19 August 2017

Peter Kelleher

16

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Europe PubMed Central

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19 August 2017

Hydroxychloroquine Trial Team

17

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Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

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publication date

1 July 2012

1 reference

Europe PubMed Central

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19 August 2017

The Journal of the American Medical Association

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Europe PubMed Central

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19 August 2017

308

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Europe PubMed Central

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19 August 2017

4

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19 August 2017

353-361

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Europe PubMed Central

PMC publication ID

19 August 2017

Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Biomarkers of immune dysfunction in HIV

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Reduction of immune activation with chloroquine therapy during chronic HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Chloroquine modulates HIV-1-induced plasmacytoid dendritic cell alpha interferon: implication for T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Inflammatory and coagulation biomarkers and mortality in patients with HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

In vitro inhibition of human influenza A virus replication by chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Inhibition of endosomal/lysosomal degradation increases the infectivity of human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Long-term effectiveness of antimalarial drugs in rheumatic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Inhibition of Human Immunodeficiency Virus Infectivity by Chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

6 September 2017

Anti-HIV effects of chloroquine: mechanisms of inhibition and spectrum of activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

28 September 2017

Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

28 September 2017

Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

28 September 2017

Hydroxychloroquine drastically reduces immune activation in HIV-infected, antiretroviral therapy-treated immunologic nonresponders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Hydroxychloroquine, hydroxyurea and didanosine as initial therapy for HIV-infected patients with low viral load: safety, efficacy and resistance profile after 144 weeks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Hydroxychloroquine for the treatment of chronic graft-versus-host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Conditioned immune response to interferon-gamma in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Comparison of hydroxychloroquine with zidovudine in asymptomatic patients infected with human immunodeficiency virus type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Hydroxychloroquine treatment of patients with human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Inhibition of human immunodeficiency virus type 1 replication by hydroxychloroquine in T cells and monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

26 June 2018

Hydroxychloroquine, hydroxycarbamide, and didanosine as economic treatment for HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

3 September 2018

The effect of hydroxychloroquine on alloreactivity and its potential use for graft-versus-host disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

3 September 2018

CD8+ lymphocyte activation at human immunodeficiency virus type 1 seroconversion: development of HLA-DR+ CD38- CD8+ cells is associated with subsequent stable CD4+ cell levels. The Multicenter AIDS Cohort Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

3 September 2018

Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

20 October 2018

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3821003

3 December 2018

Multiplex immune serum biomarker profiling in sarcoidosis and systemic sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22820788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized trial of hydroxychloroquine in early rheumatoid arthritis: the HERA Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22820788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of

1 reference

https://pubmed.ncbi.nlm.nih.gov/22820788

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1001/JAMA.2012.6936

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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