The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity (Q37216462)

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scientific article published on 19 March 2013

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English	The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity	scientific article published on 19 March 2013

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scholarly article

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Europe PubMed Central

PMC publication ID

19 August 2017

The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity (English)

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Europe PubMed Central

PMC publication ID

19 August 2017

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3

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Jakub Krijt

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Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Heather B Roman

1

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Europe PubMed Central

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19 August 2017

Lawrence L Hirschberger

2

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19 August 2017

Alessandro Valli

4

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19 August 2017

Viktor Kožich

5

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19 August 2017

Martha H Stipanuk

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19 August 2017

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19 March 2013

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19 August 2017

Antioxidants & Redox Signaling

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19 August 2017

19

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19 August 2017

12

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Europe PubMed Central

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19 August 2017

1321-1336

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Europe PubMed Central

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19 August 2017

Human sulfide:quinone oxidoreductase catalyzes the first step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

H₂S signalling through protein sulfhydration and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Physiological implications of hydrogen sulfide: a whiff exploration that blossomed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Hydrogen sulfide in biochemistry and medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Extrahepatic tissues compensate for loss of hepatic taurine synthesis in mice with liver-specific knockout of cysteine dioxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

A practical look at the chemistry and biology of hydrogen sulfide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Sulphide quinone reductase contributes to hydrogen sulphide metabolism in murine peripheral tissues but not in the CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Emerging role of hydrogen sulfide in health and disease: critical appraisal of biomarkers and pharmacological tools

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

PLP-dependent H2S biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Hydrogen sulfide and cell signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Determination of cystathionine beta-synthase activity in human plasma by LC-MS/MS: potential use in diagnosis of CBS deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Taurine in health and diseases: consistent evidence from experimental and epidemiological studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Taurine and the renal system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Physiological roles of taurine in heart and muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Role of taurine in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Ethylmalonic encephalopathy: application of improved biochemical and molecular diagnostic approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Measurement of Cysteine Dioxygenase Activity and Protein Abundance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Making and working with hydrogen sulfide: The chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Sulfite oxidizing enzymes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

The taurine transporter: mechanisms of regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Differential regulation of glutamate-cysteine ligase subunit expression and increased holoenzyme formation in response to cysteine deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Experimental animal urine collection: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Murine cysteine dioxygenase gene: structural organization, tissue-specific expression and promoter identification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

Structural organization and tissue-specific expression of the gene encoding rat cysteine dioxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

6 September 2017

The taurine and hypotaurine content of human semen

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6 September 2017

Purification and steady-state kinetic analysis of yeast thiosulfate reductase

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6 September 2017

Cat liver cystathionase

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6 September 2017

Chronic exposure to sulfide causes accelerated degradation of cytochrome c oxidase in ethylmalonic encephalopathy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

14 September 2017

Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes.

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14 September 2017

Metabolism of sulfur-containing amino acids

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14 September 2017

Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase

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14 September 2017

Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC-MS/MS and evaluation of their stability in mice tissues.

1 reference

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26 June 2018

Specificity and some other properties of liver serine sulphhydrase: Evidence for its identity with cystathionine β-synthase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791055

26 June 2018

Morphologic evidence of diffuse vascular damage in human and in the experimental model of ethylmalonic encephalopathy

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3 September 2018

The effects of taurine, taurine homologs and hypotaurine on cell and membrane antioxidative system alterations caused by type 2 diabetes in rat erythrocytes

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3 September 2018

Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria.

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3 September 2018

Regulation of cysteine dioxygenase and gamma-glutamylcysteine synthetase is associated with hepatic cysteine level

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3 September 2018

Urinary sulfur excretion and the nitrogen/sulfur balance ratio reveal nonprotein sulfur amino acid retention in piglets

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3 September 2018

Cysteine metabolism in periportal and perivenous hepatocytes: perivenous cells have greater capacity for glutathione production and taurine synthesis but not for cysteine catabolism

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3 September 2018

Enzymes and metabolites of cysteine metabolism in nonhepatic tissues of rats show little response to changes in dietary protein or sulfur amino acid levels

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3 September 2018

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3 September 2018

Endogenous hydrogen sulfide overproduction in Down syndrome

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https://pubmed.ncbi.nlm.nih.gov/23350603

12 December 2020

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Effects of nonsulfur and sulfur amino acids on the regulation of hepatic enzymes of cysteine metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23350603

12 December 2020

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Response of the kitten to dietary taurine depletion: effects on renal reabsorption, bile acid conjugation and activities of enzymes involved in taurine synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23350603

12 December 2020

based on heuristic

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A simple screening test for sulfite oxidase deficiency: Detection of urinary thiosulfate by a modification of sörbo's method

1 reference

https://pubmed.ncbi.nlm.nih.gov/23350603

12 December 2020

based on heuristic

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Free Amino Acid Composition of Porcine Seminal, Epididymal and Seminal Vesicle Fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/23350603

12 December 2020

based on heuristic

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Endogenous generation of sulfur dioxide in rat tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/23350603

12 December 2020

based on heuristic

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Identifiers

10.1089/ARS.2012.5010

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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