Mounting Pressure in the Microenvironment: Fluids, Solids, and Cells in Pancreatic Ductal Adenocarcinoma (Q37119287)

18 August 2017

Mounting Pressure in the Microenvironment: Fluids, Solids, and Cells in Pancreatic Ductal Adenocarcinoma (English)

1 reference

18 August 2017

1 reference

1 reference

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3 June 2020

Christopher C DuFort

1 reference

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3 June 2020

Kathleen E DelGiorno

series ordinal

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3 June 2020

language of work or name

English

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publication date

9 April 2016

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18 August 2017

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3 June 2020

volume

150

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3 June 2020

issue

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3 June 2020

page(s)

1545-1557.e2

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Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

3 June 2020

cites work

1 reference

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Stromal reengineering to treat pancreas cancer

14 September 2017

1 reference

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Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

14 September 2017

1 reference

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Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

14 September 2017

1 reference

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Influence of water content and drying on the physical structure of native hyaluronan.

14 September 2017

1 reference

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Genetically engineered mouse models of pancreatic adenocarcinoma

14 September 2017

1 reference

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Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer.

14 September 2017

1 reference

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Genetically engineered cancer models, but not xenografts, faithfully predict anticancer drug exposure in melanoma tumors

14 September 2017

1 reference

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Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

14 September 2017

1 reference

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Modeling and predicting clinical efficacy for drugs targeting the tumor milieu

14 September 2017

1 reference

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High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts

14 September 2017

1 reference

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Heterogeneity of the tumor vasculature: the need for new tumor blood vessel type-specific targets

14 September 2017

1 reference

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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

14 September 2017

1 reference

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

14 September 2017

1 reference

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Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression

14 September 2017

1 reference

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Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look

14 September 2017

1 reference

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Balancing forces: architectural control of mechanotransduction

14 September 2017

1 reference

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Hallmarks of Cancer: The Next Generation

14 September 2017

1 reference

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The extracellular matrix at a glance

14 September 2017

1 reference

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14 September 2017

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Desmoplasia of pancreatic ductal adenocarcinoma

14 September 2017

1 reference

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

14 September 2017

1 reference

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Mouse xenograft models vs GEM models for human cancer therapeutics

14 September 2017

1 reference

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Measuring interstitial fluid pressure with fiberoptic pressure transducers

14 September 2017

1 reference

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Tumor stroma and regulation of cancer development

14 September 2017

1 reference

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The mighty mouse: genetically engineered mouse models in cancer drug development

14 September 2017

1 reference

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Genetically engineered models have advantages over xenografts for preclinical studies

14 September 2017

1 reference

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A simple method for measuring interstitial fluid pressure in cancer tissues

14 September 2017

1 reference

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

14 September 2017

1 reference

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Stromal fibroblasts in cancer initiation and progression

14 September 2017

1 reference

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High interstitial fluid pressure - an obstacle in cancer therapy

14 September 2017

1 reference

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Hyaluronan: from extracellular glue to pericellular cue.

14 September 2017

1 reference

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Pathology: cancer cells compress intratumour vessels.

14 September 2017

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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

14 September 2017

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Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

14 September 2017

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Signaling properties of hyaluronan receptors

14 September 2017

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The microenvironment of the tumour-host interface

14 September 2017

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Openings between defective endothelial cells explain tumor vessel leakiness

14 September 2017

1 reference

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Enhancement of fluid filtration across tumor vessels: implication for delivery of macromolecules

14 September 2017

1 reference

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Interstitial-lymphatic mechanisms in the control of extracellular fluid volume.

14 September 2017

1 reference

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Progress toward resolving the controversy of positive Vs. negative interstitial fluid pressure

14 September 2017

1 reference

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

14 September 2017

1 reference

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Transport of molecules across tumor vasculature

14 September 2017

1 reference

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Clinical uses of hyaluronan

14 September 2017

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14 September 2017

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Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities

14 September 2017

1 reference

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Hyaluronan‐binding proteins in development, tissue homeostasis, and disease

14 September 2017

1 reference

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Interstitial fluid pressure

14 September 2017

1 reference

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Transport of molecules in the tumor interstitium: a review

14 September 2017

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General descriptions of passive transport of neutral solute and solvent through membranes

14 September 2017

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Technology and application of ultraminiature catheter pressure transducers.

14 September 2017

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Starling: the formulation of his hypothesis of microvascular fluid exchange and its significance after 100 years

29 September 2017

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Response to Chauhan et Al.: interstitial pressure and vascular collapse in pancreas cancer-fluids and solids, measurement and meaning

29 September 2017

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Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure

27 June 2018

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Hydration dynamics of hyaluronan and dextran

27 June 2018

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Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models

27 June 2018

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THE PRESSURE AND INTERSTITIAL RESISTANCE PREVAILING IN THE NORMAL AND EDEMATOUS SKIN OF ANIMALS AND MAN

27 June 2018

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A structural function of mucopolysaccharide in connective tissue

27 June 2018

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27 June 2018

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Interstitial Fluid Pressure: III. Its Effect on Resistance to Tissue Fluid Mobility

27 June 2018

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The effects of hyaluronidase on interstitial hydration, plasma protein exclusion, and microvascular permeability in the isolated perfused rat heart.

27 June 2018

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Effects of chlorcyclizine-induced glycosaminoglycan alterations on patterns of hyaluronate distribution during morphogenesis of the mouse secondary palate

27 June 2018

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Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy

27 June 2018

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Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer.

27 June 2018

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Morphogenesis. The Cellular and Molecular Processes of Developmental Anatomy. Jonathan Bard. Cambridge University Press, New York, 1990. xii, 303 pp., illus. $54.50. Developmental and Cell Biology Series.

3 September 2018

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Disruption of Id1 reveals major differences in angiogenesis between transplanted and autochthonous tumors.

3 September 2018

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Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors

3 September 2018

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POLYELECTROLYTES AND THEIR BIOLOGICAL INTERACTIONS.

3 September 2018

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A physical interpretation of the phenomenological coefficients of membrane permeability

3 September 2018

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Interstitial stress and fluid pressure within a growing tumor

3 September 2018

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Hyaluronidase additional to standard chemotherapy improves outcome for children with malignant brain tumors

3 September 2018

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The impact of extracellular matrix on the chemoresistance of solid tumors--experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy.

3 September 2018

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Hyaluronidase reduces the interstitial fluid pressure in solid tumours in a non-linear concentration-dependent manner.

3 September 2018

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Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor

3 September 2018

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The composition and physicochemical properties of hyaluronic acids prepared from ox synovial fluid and from a case of mesothelioma

3 September 2018

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On the Absorption of Fluids from the Connective Tissue Spaces

3 September 2018

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Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo

4 December 2018

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12 December 2020

Metaphylactic effect of mitomycin C with and without hyaluronidase after transurethral resection of bladder cancer: randomized trial

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12 December 2020

Oxygen radicals, enzymes, and fluid transport through pericardial interstitium

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12 December 2020

Negative pressure in the interstitial fluid of animals. Fluid tensions are spectacular in plants; in animals they are elusively small, but just as vital

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12 December 2020

Interstitial fluid pressure in rats measured with a modified wick technique

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12 December 2020

Thermodynamic analysis of the permeability of biological membranes to non-electrolytes

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12 December 2020

The morphogenesis of the ciliary body of the avian eye. II. Differential enlargement causes an epithelium to form radial folds

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Rheology of sodium hyaluronate under physiological conditions

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A concept of negative interstitial pressure based on pressures in implanted perforated capsules

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Hyaluronidase enhances the therapeutic effect of vinblastine in intralesional treatment of Kaposi's sarcoma. Military Medical Consortium for the Advancement of Retroviral Research (MMCARR)

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12 December 2020

INTERSTITIAL FLUID PRESURE. II. PRESSURE-VOLUME CURVES OF INTERSTITIAL SPACE

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12 December 2020

Effects of hyaluronidase on doxorubicin penetration into squamous carcinoma multicellular tumor spheroids and its cell lethality

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12 December 2020

Solid stress inhibits the growth of multicellular tumor spheroids

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12 December 2020

The morphogenesis of the ciliary body of the avian eye. I. Lateral cell detachment facilitates epithelial folding

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12 December 2020

Hyaluronate production and removal during corneal development in the chick

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12 December 2020

Hyaluronidase as additive to induction chemotherapy in advanced squamous cell carcinoma of the head and neck

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12 December 2020

The significance of the tissue pressure of normal testicular and of neoplastic (Brown-Pearce carcinoma) tissue in the rabbit

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12 December 2020

10.1053/J.GASTRO.2016.03.040

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27072672%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27072672%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

PubMed publication ID

27072672

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27072672%20AND%20SRC:MED&resulttype=core&format=json