Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET. (Q37105874)

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scientific article published on February 2009

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English	Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.	scientific article published on February 2009

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19 January 2020

Single-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET (English)

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19 January 2020

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19 January 2020

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Emmanuelle Briard

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19 January 2020

Sami S Zoghbi

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19 January 2020

Fabrice G Siméon

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19 January 2020

Masao Imaizumi

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19 January 2020

Jonathan P Gourley

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19 January 2020

H Umesha Shetty

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19 January 2020

Masahiro Fujita

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19 January 2020

Robert B Innis

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19 January 2020

Victor W Pike

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19 January 2020

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1 February 2009

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19 January 2020

Journal of Medicinal Chemistry

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19 January 2020

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19 January 2020

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19 January 2020

688-699

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19 January 2020

Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

14 September 2017

Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors

1 reference

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Positron emission tomography imaging of neuroinflammation

1 reference

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14 September 2017

The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging

1 reference

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14 September 2017

Development of ligands for the peripheral benzodiazepine receptor

1 reference

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14 September 2017

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

1 reference

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14 September 2017

Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders.

1 reference

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14 September 2017

Peripheral benzodiazepine receptor ligands: mitochondrial transmembrane potential depolarization and apoptosis induction in rat C6 glioma cells

1 reference

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14 September 2017

Design, synthesis and structure-affinity relationships of aryloxyanilide derivatives as novel peripheral benzodiazepine receptor ligands

1 reference

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14 September 2017

Involvement of benzodiazepine receptors in neuroinflammatory and neurodegenerative diseases: evidence from activated microglial cells in vitro

1 reference

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14 September 2017

Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents

1 reference

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Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography

1 reference

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14 September 2017

Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

14 September 2017

The role of peripheral benzodiazepine receptors (PBRs) in CNS pathophysiology

1 reference

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14 September 2017

Neuropharmacological profile of peripheral benzodiazepine receptor agonists, DAA1097 and DAA1106.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

14 September 2017

Benzodiazepines, anxiety and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

14 September 2017

Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

14 September 2017

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

14 September 2017

High densities of benzodiazepine receptors in human cortical areas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

14 September 2017

Photodynamic tumor therapy: mitochondrial benzodiazepine receptors as a therapeutic target.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

27 June 2018

Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

27 June 2018

Distribution profile and properties of peripheral-type benzodiazepine receptors on human hemopoietic cells

1 reference

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27 June 2018

Evidence for species differences in 'peripheral' benzodiazepine receptors: an autoradiographic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

27 June 2018

Peripheral type benzodiazepine binding sites are a sensitive indirect index of neuronal damage

1 reference

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27 June 2018

In vivo binding to peripheral benzodiazepine binding sites in lesioned rat brain: comparison between [3H]PK11195 and [18F]PK14105 as markers for neuronal damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

27 June 2018

Macrophage and astrocyte populations in relation to [3H]PK 11195 binding in rat cerebral cortex following a local ischaemic lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

27 June 2018

Characterization of benzodiazepine binding sites in cultured cells of neural origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

27 June 2018

Synthesis and biological evaluation of substituted [18F]imidazo[1,2-a]pyridines and [18F]pyrazolo[1,5-a]pyrimidines for the study of the peripheral benzodiazepine receptor using positron emission tomography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

3 September 2018

Synthesis, fluorine-18 radiolabeling, and in vitro characterization of 1-iodophenyl-N-methyl-N-fluoroalkyl-3-isoquinoline carboxamide derivatives as potential PET radioligands for imaging peripheral benzodiazepine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

3 September 2018

Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

3 September 2018

Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

3 September 2018

Radiation dosimetry and biodistribution in monkey and man of 11C-PBR28: a PET radioligand to image inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

3 September 2018

Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

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1 reference

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Quantitative analyses of 18F-FEDAA1106 binding to peripheral benzodiazepine receptors in living human brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

3 September 2018

Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

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Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoroethyl-5-methoxybenzyl)acetamide, for pet imaging of peripheral benzodiazepine receptor in primate brain

1 reference

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3 September 2018

[(11)C]DAA1106: radiosynthesis and in vivo binding to peripheral benzodiazepine receptors in mouse brain

1 reference

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3 September 2018

[18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

3 September 2018

Binding characteristics of [3H]DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors

1 reference

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3 September 2018

Peripheral-type benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646257

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Synthesis and murine tissue uptake of sodium [18F]fluoroacetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19119848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of peripheral-type benzodiazepine binding sites on human erythrocyte membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19119848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Peripheral-Type Benzodiazepine Receptors in the Intracellular Transport of Heme and Porphyrins1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19119848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific high-affinity saturable binding of [3H] R05-4864 to benzodiazepine binding sites in the rat cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19119848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral-type benzodiazepine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19119848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positron-emitting radioligands for studies in vivo-probes for human psychopharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19119848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The radiosynthesis of [18F]PK 14105 as an alternative radioligand for peripheral type benzodiazepine binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/19119848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1021/JM8011855

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19 January 2020

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19 January 2020

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19 January 2020

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