Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice (Q37068311)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19104057%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice (English)

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19 January 2020

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19 January 2020

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19 January 2020

Melinda S Yates

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19 January 2020

Tirumalai Rangasamy

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19 January 2020

David J Blake

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19 January 2020

Deepti Malhotra

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19 January 2020

Hazim El-Haddad

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19 January 2020

Djahida Bedja

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19 January 2020

Ponvijay Kombairaju

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19 January 2020

Masayuki Yamamoto

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19 January 2020

Michael B Sporn

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19 January 2020

Kathleen L Gabrielson

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19 January 2020

Hunter C Champion

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19 January 2020

Rubin M Tuder

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19 January 2020

Thomas W Kensler

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19 January 2020

Shyam Biswal

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19 January 2020

language of work or name

English

0 references

publication date

22 December 2008

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19 January 2020

number of pages

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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19 January 2020

volume

106

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19 January 2020

issue

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19 January 2020

page(s)

250-255

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Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease

19 January 2020

cites work

1 reference

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Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

29 September 2017

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Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1

29 September 2017

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Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice

29 September 2017

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29 September 2017

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Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

29 September 2017

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Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

29 September 2017

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Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

29 September 2017

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The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells

29 September 2017

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Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms

29 September 2017

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The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling

29 September 2017

1 reference

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Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial

29 September 2017

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Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress

29 September 2017

1 reference

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Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

29 September 2017

1 reference

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Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

29 September 2017

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Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease?

29 September 2017

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Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

29 September 2017

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Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial

29 September 2017

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The pathogenesis of emphysema: the elastase:antielastase hypothesis 30 years later.

29 September 2017

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Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part One.

29 September 2017

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Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide

29 September 2017

1 reference

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The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease

27 June 2018

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Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema

4 September 2018

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4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

4 September 2018

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Lipid peroxidation and glutathione peroxidase activity in chronic obstructive pulmonary disease exacerbation: prognostic value of malondialdehyde

4 September 2018

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Long-term treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking. European Respiratory Society Study on Chronic Obstructive Pulmonary Disease

4 September 2018

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Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers

4 September 2018

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Systemic oxidative stress in asthma, COPD, and smokers

4 December 2018

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Effect of inhaled triamcinolone on the decline in pulmonary function in chronic obstructive pulmonary disease

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19104057

12 December 2020

inferred from PubMed ID database lookup

Control of Drosophila head segment identity by the bZIP homeotic gene cnc

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19104057

12 December 2020

inferred from PubMed ID database lookup

Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19104057

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0804333106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19104057%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

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19 January 2020

PubMed publication ID

19104057

1 reference

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