Rheb/mTORC1 signaling promotes kidney fibroblast activation and fibrosis (Q36977335)

17 August 2017

Rheb/mTORC1 signaling promotes kidney fibroblast activation and fibrosis (English)

1 reference

17 August 2017

Lei Jiang

1 reference

17 August 2017

Lingling Xu

1 reference

17 August 2017

Junhua Mao

1 reference

17 August 2017

Jianzhong Li

1 reference

17 August 2017

Li Fang

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17 August 2017

Yang Zhou

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17 August 2017

Wei Liu

1 reference

17 August 2017

Weichun He

1 reference

17 August 2017

Allan Zijian Zhao

1 reference

17 August 2017

Junwei Yang

1 reference

17 August 2017

Chunsun Dai

1 reference

17 August 2017

language of work or name

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9 May 2013

1 reference

Journal of the American Society of Nephrology

17 August 2017

1 reference

17 August 2017

1 reference

17 August 2017

1 reference

17 August 2017

1114-1126

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3699820/fullTextXML

inferred from PubMed Central ID database lookup

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Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver

29 September 2017

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mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression

29 September 2017

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Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

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Failure to ubiquitinate c-Met leads to hyperactivation of mTOR signaling in a mouse model of autosomal dominant polycystic kidney disease

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Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Critical role for hypothalamic mTOR activity in energy balance

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis

29 September 2017

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Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.

29 September 2017

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Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1.

29 September 2017

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PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR

29 September 2017

1 reference

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The tuberous sclerosis complex

29 September 2017

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

29 September 2017

1 reference

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Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway

29 September 2017

1 reference

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Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699820

Evidence that fibroblasts derive from epithelium during tissue fibrosis

29 September 2017

1 reference

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Determination of absolute amounts of GDP and GTP bound to Ras in mammalian cells: comparison of parental and Ras-overproducing NIH 3T3 fibroblasts

29 September 2017

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Anatomy of the renal interstitium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699820

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

29 September 2017

1 reference

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Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy

27 June 2018

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Rapamycin plays a new role as differentiator of vascular smooth muscle phenotype. focus on "The mTOR/p70 S6K1 pathway regulates vascular smooth muscle differentiation".

4 September 2018

1 reference

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Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699820

Molecular insights into renal interstitial fibrosis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3699820

Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats

20 October 2018

1 reference

12 December 2020

A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections

1 reference

12 December 2020

Renal fibroblast culture

1 reference

12 December 2020

Rapamycin and chronic kidney disease: beyond the inhibition of inflammation

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12 December 2020

IL-1β induces VEGF, independently of PGE2 induction, mainly through the PI3-K/mTOR pathway in renal mesangial cells

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12 December 2020

Identifiers

DOI

10.1681/ASN.2012050476

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

23661807

1 reference