Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase. (Q36951981)

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3 April 2020

title

Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase (English)

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Annica Pschibul

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Cheng-Tsung Lai

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Maria Hirschbeck

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Jochen Kuper

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Shabnam Davoodi

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Junjie Zou

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Nina Liu

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Pan Pan

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Sonam Shah

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Fereidoon Daryaee

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Gopal R Bommineni

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Cristina Lai

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Carlos Simmerling

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language of work or name

English

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publication date

17 May 2016

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volume

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issue

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page(s)

2992-3006

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Direct inhibitors of InhA are active against Mycobacterium tuberculosis.

3 April 2020

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How good are my data and what is the resolution?

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Structure of the Yersinia pestis FabV Enoyl-ACP Reductase and Its Interaction with Two 2-Pyridone Inhibitors

9 September 2017

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Determination of the Crystal Structure and Active Residues of FabV, the Enoyl-ACP Reductase from Xanthomonas oryzae

9 September 2017

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Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors.

9 September 2017

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9 September 2017

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Mechanism and inhibition of the FabI enoyl-ACP reductase from Burkholderia pseudomallei

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A Slow, Tight Binding Inhibitor of InhA, the Enoyl-Acyl Carrier Protein Reductase from Mycobacterium tuberculosis

9 September 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

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9 September 2017

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9 September 2017

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Mechanism and inhibition of the FabV enoyl-ACP reductase from Burkholderia mallei

9 September 2017

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Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase

9 September 2017

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Plague into the 21st century

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Slow-Onset Inhibition of the FabI Enoyl Reductase from Francisella tularensis : Residence Time and in Vivo Activity

9 September 2017

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Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors

9 September 2017

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Bioterrorism: class A agents and their potential presentations in immunocompromised patients

9 September 2017

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Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus

9 September 2017

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9 September 2017

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Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase

9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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Enzymatic characterization of the target for isoniazid in Mycobacterium tuberculosis

9 September 2017

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6 Statistical analysis of enzyme kinetic data

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Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald

9 September 2017

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29 September 2017

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Phenylimidazole derivatives of 4-pyridone as dual inhibitors of bacterial enoyl-acyl carrier protein reductases FabI and FabK.

29 September 2017

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The kalimantacin/batumin biosynthesis operon encodes a self-resistance isoform of the FabI bacterial target

29 September 2017

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In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea

27 June 2018

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27 June 2018

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27 June 2018

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Essentiality of FASII pathway for Staphylococcus aureus

27 June 2018

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Discovery of 4-Pyridone derivatives as specific inhibitors of enoyl-acyl carrier protein reductase (FabI) with antibacterial activity against Staphylococcus aureus.

4 September 2018

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4 September 2018

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Structure-activity studies of the inhibition of FabI, the enoyl reductase from Escherichia coli, by triclosan: kinetic analysis of mutant FabIs.

4 September 2018

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Transferable plasmid-mediated resistance to streptomycin in a clinical isolate of Yersinia pestis

4 September 2018

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Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis, by triclosan and isoniazid.

4 September 2018

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Protein EnvM is the NADH-dependent enoyl-ACP reductase (FabI) of Escherichia coli.

4 September 2018

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4 September 2018

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4 September 2018

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4 December 2018

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High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains ofMycobacterium tuberculosis

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Role of binding energy with coenzyme A in catalysis by 3-oxoacid coenzyme A transferase

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Preparative enzymatic synthesis of acyl-acyl carrier protein

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10.1021/ACS.BIOCHEM.5B01301

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27136302%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27136302%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

PubMed publication ID

27136302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27136302%20AND%20SRC:MED&resulttype=core&format=json