Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle (Q36924317)

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12 February 2020

title

Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle (English)

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12 February 2020

Micah J Drummond

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12 February 2020

Kyle L Timmerman

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12 February 2020

Christopher S Fry

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12 February 2020

Jared M Dickinson

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David M Gundermann

series ordinal

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Dillon K Walker

series ordinal

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publication date

6 September 2012

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volume

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issue

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page(s)

144-151

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Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

12 February 2020

cites work

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Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

29 September 2017

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Regulation of protein synthesis by amino acids in muscle of neonates

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Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women

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Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

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Sequential muscle biopsies during a 6-h tracer infusion do not affect human mixed muscle protein synthesis and muscle phenylalanine kinetics.

29 September 2017

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Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation

29 September 2017

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

29 September 2017

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Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle.

29 September 2017

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FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

29 September 2017

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FoxO3 controls autophagy in skeletal muscle in vivo

29 September 2017

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How to interpret LC3 immunoblotting

29 September 2017

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Sirolimus (rapamycin): from the soil of Easter Island to a bright future

29 September 2017

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Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: a systematic review and meta-analysis of randomized trials

29 September 2017

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Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

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29 September 2017

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Sirolimus for Kaposi's sarcoma in renal-transplant recipients

29 September 2017

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Age and aerobic exercise training effects on whole body and muscle protein metabolism

29 September 2017

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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

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Leucine limitation induces autophagy and activation of lysosome-dependent proteolysis in C2C12 myotubes through a mammalian target of rapamycin-independent signaling pathway

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29 September 2017

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Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men.

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4 September 2018

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4 September 2018

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4 September 2018

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Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway

4 September 2018

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Mixed muscle protein synthesis and breakdown after resistance exercise in humans

4 September 2018

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The determination of low d5-phenylalanine enrichment (0.002-0.09 atom percent excess), after conversion to phenylethylamine, in relation to protein turnover studies by gass chromatography/electron ionization mass spectrometry

4 September 2018

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Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

4 September 2018

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12 December 2020

Involvement of the rapamycin-sensitive pathway in the insulin regulation of muscle protein synthesis in streptozotocin-diabetic rats.

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12 December 2020

Sirolimus experience in heart transplantation

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12 December 2020

Measurement of very low stable isotope enrichments by gas chromatography/mass spectrometry: application to measurement of muscle protein synthesis

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The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth

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12 December 2020

10.1016/J.METABOL.2012.07.003

Identifiers

DOI

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12 February 2020

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12 February 2020

PubMed publication ID

22959478

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