Psoriasis: evolution of pathogenic concepts and new therapies through phases of translational research (Q36917184)

17 August 2017

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title

Psoriasis: evolution of pathogenic concepts and new therapies through phases of translational research (English)

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17 August 2017

Guttman-Yassky E

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17 August 2017

Krueger JG

series ordinal

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17 August 2017

language of work or name

English

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publication date

21 August 2007

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British Journal of Dermatology

17 August 2017

published in

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17 August 2017

volume

157

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17 August 2017

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17 August 2017

page(s)

1103-1115

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Markers for proliferation and keratinization in the margin of the active psoriatic lesion

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

The Binding of Helix pomatia and Ulex europeus Agglutinins to Normal and Psoriatic Skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Phototherapy for psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Management of psoriasis vulgaris with methotrexate 0.25% in a hydrophilic gel: a placebo-controlled, double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Retinoids and psoriasis: novel issues in retinoid pharmacology and implications for psoriasis treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Effect of 1 alpha,25-dihydroxyvitamin D3 on the morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown in serum-free conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Treatment of psoriasis by the topical application of the novel cholecalciferol analogue calcipotriol (MC 903)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Calcipotriol (MC 903), a novel vitamin D3 analogue stimulates terminal differentiation and inhibits proliferation of cultured human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Role of the microcirculation in the treatment and pathogenesis of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Continuous cultures of fused cells secreting antibody of predefined specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Expression of HLA-DR molecules by keratinocytes, and presence of Langerhans cells in the dermal infiltrate of active psoriatic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

The pathogenesis of psoriasis: immunological facts and speculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

The immunologic basis for the treatment of psoriasis with new biologic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Biologic effects of topical calcipotriol (MC 903) treatment in psoriatic skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

The role of leukotrienes in inflammation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

CD4 antibody treatment of severe psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Tacrolimus (FK 506)--a new therapeutic agent for severe recalcitrant psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

A major factor contributing to epidermal proliferation in inflammatory skin diseases appears to be interleukin 1 or a related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interleukin-6 in psoriasis: expression and mitogenicity studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interferon-gamma, a strong suppressor of cell proliferation, induces upregulation of keratin K6, one of the inflammatory- and proliferation-associated keratins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Multiple members of the TNF superfamily contribute to IFN-gamma-mediated inhibition of erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Successful ultraviolet B treatment of psoriasis is accompanied by a reversal of keratinocyte pathology and by selective depletion of intraepidermal T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Psoriasis: emerging therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Methotrexate therapy of psoriasis: differential sensitivity of proliferating lymphoid and epithelial cells to the cytotoxic and growth-inhibitory effects of methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

A rapid flow cytometric assay to detect CD4+ and CD8+ T-helper (Th) 0, Th1 and Th2 cells in whole blood and its application to study cytokine levels in atopic dermatitis before and after cyclosporin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Elevated rate of Thelper1 (TH1) lymphocytes and serum IFN-γ levels in psoriatic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Cytokines: interleukin and interferon therapy in dermatology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interleukin-10: an important immunoregulatory cytokine with major impact on psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: a case series.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interleukin-12 to interleukin 'infinity': the rationale for future therapeutic cytokine targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Regulatory T cells control the development of allergic disease and asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Regulatory CD4+ T cells and the control of autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Neuropilin-1: a surface marker of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

IL-22 increases the innate immunity of tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Steady-state and inflammatory dendritic-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Production of type I interferons: plasmacytoid dendritic cells and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Cdk5 Modulation of mitogen-activated protein kinase signaling regulates neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Interleukin 20: discovery, receptor identification, and role in epidermal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Mouse models of psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

High expression levels of keratinocyte antimicrobial proteins in psoriasis compared with atopic dermatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Activator protein 1 DNA binding activity is decreased in lesional psoriatic skin compared with nonlesional psoriatic skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Of mice and not men: differences between mouse and human immunology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Genetics of psoriasis: paternal inheritance and a locus on chromosome 6p.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Psoriasis: genetic associations and immune system changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva): mechanisms of action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Novel insight into the agonistic mechanism of alefacept in vivo: differentially expressed genes may serve as biomarkers of response in psoriasis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

Pulling the trigger on psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2133.2007.08135.X

10.1111/J.1365-2133.2007.08135.X

21 January 2018

Identifiers

DOI

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17 August 2017

1 reference