High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma (Q36893712)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780787%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma (English)

1 reference

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13 January 2020

1 reference

1 reference

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13 January 2020

Erik Fredlund

1 reference

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13 January 2020

John M Maris

series ordinal

1 reference

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13 January 2020

Sven Påhlman

series ordinal

1 reference

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13 January 2020

language of work or name

English

0 references

publication date

9 September 2008

1 reference

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13 January 2020

number of pages

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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13 January 2020

volume

105

1 reference

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13 January 2020

issue

1 reference

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13 January 2020

page(s)

14094-14099

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780787%20AND%20SRC:MED&resulttype=core&format=json

The Transformation of a Malignant Paravertebral Sympathicoblastoma into a Benign Ganglioneuroma

13 January 2020

cites work

1 reference

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Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification

29 September 2017

1 reference

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Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation

29 September 2017

1 reference

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Revealing signaling pathway deregulation by using gene expression signatures and regulatory motif analysis.

29 September 2017

1 reference

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Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.

29 September 2017

1 reference

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Developing gene expression signatures of pathway deregulation in tumors

29 September 2017

1 reference

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Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

29 September 2017

1 reference

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The sympathoadrenal cell lineage: specification, diversification, and new perspectives

29 September 2017

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Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation

29 September 2017

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The MYCN enigma: significance of MYCN expression in neuroblastoma

29 September 2017

1 reference

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Chromosome 1p and 11q deletions and outcome in neuroblastoma

29 September 2017

1 reference

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Oncogenic pathway signatures in human cancers as a guide to targeted therapies

29 September 2017

1 reference

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A review of DNA microarray analysis of human neuroblastomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation

29 September 2017

1 reference

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Neural crest specification: migrating into genomics

29 September 2017

1 reference

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An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Identification of genes that are regulated transcriptionally by Myc in childhood tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Neuroblastoma: biological insights into a clinical enigma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

The International Neuroblastoma Pathology Classification (the Shimada system).

29 September 2017

1 reference

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Histopathologic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

A developmental model of neuroblastoma: differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblastomas.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2544584

Developmental gene expression of sympathetic nervous system tumors reflects their histogenesis.

4 September 2018

1 reference

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Regulation of the neural crest cell fate by N-myc: promotion of ventral migration and neuronal differentiation.

4 September 2018

1 reference

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Immunohistochemical analysis of the Bcl-2 oncoprotein in human neuroblastomas. Comparisons with tumor cell differentiation and N-Myc protein.

4 September 2018

1 reference

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4 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0804455105

Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0804455105

Classification of neuroblastoma patients by published gene-expression markers reveals a low sensitivity for unfavorable courses of MYCN non-amplified disease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0804455105

Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0804455105

Functional homology between N-myc and c-myc in murine plasmacytomagenesis: plasmacytoma development in N-myc transgenic mice

21 January 2018

1 reference

12 December 2020

Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome

1 reference

12 December 2020

High Skp2 expression characterizes high-risk neuroblastomas independent of MYCN status

1 reference

12 December 2020

Clinical significance of a highly sensitive analysis for gene dosage and the expression level of MYCN in neuroblastoma

1 reference

12 December 2020

Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number

1 reference

12 December 2020

MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN

1 reference

12 December 2020

Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0804455105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780787%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780787%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

18780787

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18780787%20AND%20SRC:MED&resulttype=core&format=json