Targeting mast cells in endometriosis with janus kinase 3 inhibitor, JANEX-1. (Q36881600)

16 August 2017

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title

Targeting mast cells in endometriosis with janus kinase 3 inhibitor, JANEX-1. (English)

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16 August 2017

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Fatih M Uckun

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16 August 2017

Osmond J D'Cruz

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16 August 2017

publication date

1 August 2007

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American Journal of Reproductive Immunology

16 August 2017

published in

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16 August 2017

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16 August 2017

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16 August 2017

page(s)

75-97

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Endometriosis: abnormal endometrium and dysfunctional immune response.

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Evaluation of endometriosis in uterosacral ligaments by transrectal ultrasonography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Relation between pain symptoms and the anatomic location of deep infiltrating endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Endometriosis--a disease because it is characterized by bleeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Prostaglandin receptor signalling and function in human endometrial pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Thoracic endometriosis syndrome: new observations from an analysis of 110 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Environmental toxins and endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The peritoneal environment in endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Role of cytokines in endometriosis-associated infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The involvement of T lymphocytes in the pathogenesis of endometriotic tissues overgrowth in women with endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Phenotypic and functional studies of leukocytes in human endometrium and endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Pathogenesis of endometriosis: natural immunity dysfunction or autoimmune disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Marked elevation of macrophage migration inhibitory factor in the peritoneal fluid of women with endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Peritoneal fluid concentrations of epithelial neutrophil-activating peptide-78 correlate with the severity of endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Tumor necrosis factor-alpha but not interleukin-1 beta or interleukin-8 concentrations correlate with angiogenic activity of peritoneal fluid from patients with minimal to mild endometriosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Endometriotic cells are resistant to interferon-gamma-induced cell growth inhibition and apoptosis: a possible mechanism involved in the pathogenesis of endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Endometriosis and unexplained recurrent spontaneous abortion: pathological states resulting from aberrant modulation of natural killer cell function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Behaviour of cytokine levels in serum and peritoneal fluid of women with endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Uterine chemokines in reproductive physiology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Immunobiology of endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Endometriosis and inflammation in infertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Radical resection of invasive endometriosis with bowel or bladder involvement--long-term results

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

COX-2 inhibitors and their role in gynecology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The treatment with a COX-2 specific inhibitor is effective in the management of pain related to endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Cardiac risks with COX-2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The coxibs and traditional nonsteroidal anti-inflammatory drugs: a current perspective on cardiovascular risks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Cardiovascular toxicities of immunosuppressive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Developments in glucocorticoid therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Induction of endometriosis in mice: A new model sensitive to estrogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Peritoneal endometriosis: validation of an in-vivo model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Record review of baboons with histologically confirmed endometriosis in a large established colony

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Increased numbers of activated mast cells in endometriosis lesions positive for corticotropin-releasing hormone and urocortin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Light and electron microscopic evaluation of antileukotriene therapy for experimental rat endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Inflammation and hyperalgesia induced by nerve injury in the rat: a key role of mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The ins and outs of IgE-dependent mast-cell exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Proximal signaling events in Fc epsilon RI-mediated mast cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Integrated signalling pathways for mast-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The role of Th2 cytokines in mast cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Stat5 expression is required for IgE-mediated mast cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Inhibition of cytokines and JAK-STAT activation by distinct signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Jaks and Stats in signaling by the cytokine receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The role of Jak3 in lymphoid development, activation, and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Genetic and biochemical evidence for a critical role of Janus kinase (JAK)-3 in mast cell-mediated type I hypersensitivity reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Prevention of CD40-triggered dendritic cell maturation and induction of T-cell hyporeactivity by targeting of Janus kinase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Suppression of early T-cell-receptor-triggered cellular activation by the Janus kinase 3 inhibitor WHI-P-154.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Targeting JAK3 with JANEX-1 for prevention of autoimmune type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Dual targeting of Bruton's tyrosine kinase and Janus kinase 3 with rationally designed inhibitors prevents graft-versus-host disease (GVHD) in a murine allogeneic bone marrow transplantation model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Nitric Oxide Modulates Pro- and Anti-inflammatory Cytokines in Lipopolysaccharide-Activated Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The kinase inhibitor imatinib mesylate inhibits TNF-{alpha} production in vitro and prevents TNF-dependent acute hepatic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Anti-inflammatory activity of 2,4, 6-trihydroxy-alpha-p-methoxyphenyl-acetophenone (compound D-58).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Do selective COX-2 inhibitors increase the risk of cerebrovascular events? A meta-analysis of randomized controlled trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

New trends in immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The JAK3 inhibitor CP-690550 selectively reduces NK and CD8+ cell numbers in cynomolgus monkey blood following chronic oral dosing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Janus kinase 3: a novel target for selective transplant immunosupression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The novel JAK-3 inhibitor CP-690550 is a potent immunosuppressive agent in various murine models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Effects of JAK3 inhibition with CP-690,550 on immune cell populations and their functions in nonhuman primate recipients of kidney allografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

PNU156804 inhibits Jak3 tyrosine kinase and rat heart allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The levonorgestrel-releasing intrauterine system in modern gynaecology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

ESHRE guideline for the diagnosis and treatment of endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Mechanisms of endotoxin shock and endotoxin hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

ENDOMETRIOSIS AND OVULATORY DISORDER: REDUCED FERTILISATION IN VITRO COMPARED WITH TUBAL AND UNEXPLAINED INFERTILITY

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

Intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms in endometriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0897.2007.00502.X

10.1111/J.1600-0897.2007.00502.X

21 January 2018

Identifiers

DOI

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16 August 2017

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