Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists (Q36877434)

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scientific article published on 20 July 2015

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English	Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists	scientific article published on 20 July 2015

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scholarly article

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Europe PubMed Central

PMC publication ID

16 August 2017

Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists (English)

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Europe PubMed Central

PMC publication ID

16 August 2017

author name string

S Sakura Minami

1

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16 August 2017

Vivian Shen

2

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16 August 2017

David Le

3

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PMC publication ID

16 August 2017

Grietje Krabbe

4

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16 August 2017

Rustam Asgarov

5

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16 August 2017

Liberty Perez-Celajes

6

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16 August 2017

Chih-Hung Lee

7

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16 August 2017

Jinhe Li

8

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PMC publication ID

16 August 2017

Diana Donnelly-Roberts

9

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16 August 2017

Li Gan

10

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16 August 2017

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publication date

20 July 2015

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16 August 2017

Biochemical Pharmacology

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16 August 2017

97

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PMC publication ID

16 August 2017

4

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Europe PubMed Central

PMC publication ID

16 August 2017

454-462

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Europe PubMed Central

PMC publication ID

16 August 2017

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4859338/fullTextXML

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α7 Nicotinic acetylcholine receptor-specific antibody induces inflammation and amyloid β42 accumulation in the mouse brain to impair memory

1 reference

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29 September 2017

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.

1 reference

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Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress

1 reference

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The α7 nicotinic receptor agonist ABT-107 decreases L-Dopa-induced dyskinesias in parkinsonian monkeys

1 reference

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Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice

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29 September 2017

Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage

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29 September 2017

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

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Core features of frontotemporal dementia recapitulated in progranulin knockout mice

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Unphosphorylated STAT3 modulates alpha 7 nicotinic receptor signaling and cytokine production in sepsis

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29 September 2017

Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia

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29 September 2017

In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.

1 reference

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29 September 2017

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

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Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

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1 reference

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4 September 2018

Identifiers

10.1016/J.BCP.2015.07.016

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 August 2017

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