A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen (Q36833617)

16 August 2017

A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen (English)

1 reference

16 August 2017

Lonny R Levin

0 references

Jochen Buck

1 reference

16 August 2017

Clemens Steegborn

1 reference

16 August 2017

Tatiana N Litvin

1 reference

16 August 2017

Kenneth C Hess

1 reference

16 August 2017

Austin B Capper

1 reference

16 August 2017

Ronald Taussig

1 reference

16 August 2017

Hao Wu

1 reference

16 August 2017

language of work or name

English

0 references

publication date

7 July 2005

1 reference

Journal of Biological Chemistry

16 August 2017

1 reference

16 August 2017

280

1 reference

16 August 2017

1 reference

16 August 2017

31754-31759

1 reference

Bicarbonate activation of adenylyl cyclase via promotion of catalytic active site closure and metal recruitment

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Allosteric modulation of G protein-coupled receptors: perspectives and recent developments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Raster3D Version 2.0. A program for photorealistic molecular graphics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Tyrphostins are inhibitors of guanylyl and adenylyl cyclases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Cardiovascular pharmacology of estradiol metabolites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

The class III adenylyl cyclases: multi-purpose signalling modules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Metal Coordination-Based Inhibitors of Adenylyl Cyclase: Novel Potent P-Site Antagonists

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Construction of soluble adenylyl cyclase from human membrane-bound type 7 adenylyl cyclase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

CO(2)/HCO(3)(-)-responsive soluble adenylyl cyclase as a putative metabolic sensor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Regulation and role of adenylyl cyclase isoforms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Two-metal-Ion catalysis in adenylyl cyclase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

The interactions of adenylate cyclases with P-site inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Catalytic mechanism and regulation of mammalian adenylyl cyclases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Functional role of estrogen metabolism in target cells: review and perspectives

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Estrogenic responses in estrogen receptor-alpha deficient mice reveal a distinct estrogen signaling pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Structure of the adenylyl cyclase catalytic core

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

4-Hydroxylation of estrogens as marker of human mammary tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

29 September 2017

Adenylate cyclase assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Catechol oestrogens inhibit oestrogen elicited accumulation of hypothalamic cyclic AMP suggesting role as endogenous anti-oestrogens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Direct inhibition of tyrosine hydroxylase activity by catechol estrogens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Expression and purification of recombinant adenylyl cyclases in Sf9 cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Enzymatic synthesis of deoxyribonucleic acid. XXX. Binding of triphosphates to deoxyribonucleic acid polymerase

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Purification of the catalyst of adenylate cyclase

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Inhibition of the soluble form of testis adenylate cyclase by catechol estrogens and other catechols

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Catechol estrogens: presence in brain and endocrine tissues

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Allosteric inhibition of protein tyrosine phosphatase 1B.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Estrogen receptor-independent catechol estrogen binding activity: protein binding studies in wild-type, Estrogen receptor-alpha KO, and aromatase KO mice tissues

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Small ligands modulating the activity of mammalian adenylyl cyclases: a novel mode of inhibition by calmidazolium

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Purification of soluble adenylyl cyclase

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Interactions of Forskolin and ATP with the Cytosolic Domains of Mammalian Adenylyl Cyclase

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3650720

Kinetic studies of RNA-protein interactions using surface plasmon resonance.

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M507144200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M507144200

The structure, catalytic mechanism and regulation of adenylyl cyclase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16002394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Catechol estrogens as inhibitors of leukotriene synthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16002394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Isoform-specific regulation of adenylyl cyclase by oxidized catecholamines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16002394

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M507144200

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

16002394

1 reference