Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas (Q36761564)

16 August 2017

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas (English)

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16 August 2017

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Clemens A Schmitt

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Jake Shortt

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Ross D Hannan

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Carleen Cullinane

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Ricky W Johnstone

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Grant A McArthur

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Benjamin P Martin

1 reference

16 August 2017

Andrea Newbold

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16 August 2017

Katherine M Hannan

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16 August 2017

Jennifer R Devlin

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16 August 2017

Adele J Baker

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16 August 2017

Rachael Ralli

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16 August 2017

Maurice Reimann

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16 August 2017

Michael N Hall

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16 August 2017

Meaghan Wall

1 reference

16 August 2017

Richard B Pearson

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16 August 2017

language of work or name

English

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publication date

12 February 2013

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16 August 2017

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16 August 2017

121

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16 August 2017

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16 August 2017

2964-2974

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describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3624942/fullTextXML

inferred from PubMed Central ID database lookup

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The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses

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Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas

29 September 2017

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Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

29 September 2017

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An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

29 September 2017

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The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner

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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

29 September 2017

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c-myc Repression of TSC2 contributes to control of translation initiation and Myc-induced transformation

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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5 September 2018

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5 September 2018

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5 September 2018

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5 September 2018

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The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

5 September 2018

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5 September 2018

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5 September 2018

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c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

5 September 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23403624

12 December 2020

inferred from PubMed ID database lookup

Two classes of cAMP analogs which are selective for the two different cAMP-binding sites of type II protein kinase demonstrate synergism when added together to intact adipocytes

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23403624

12 December 2020

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23403624

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1182/BLOOD-2012-08-446096

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

23403624

1 reference