Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism (Q36705331)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26675708%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Mechanical signals promote osteogenic fate through a primary cilia-mediated mechanism (English)

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2 March 2020

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2 March 2020

Julia C Chen

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2 March 2020

Mardonn Chua

series ordinal

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2 March 2020

Raymond Bellon

series ordinal

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2 March 2020

Christopher R Jacobs

series ordinal

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2 March 2020

language of work or name

English

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publication date

16 December 2015

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2 March 2020

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2 March 2020

volume

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2 March 2020

issue

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2 March 2020

page(s)

1504-1511

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describes a project that uses

2 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4799506/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Mechanically stimulated bone cells secrete paracrine factors that regulate osteoprogenitor recruitment, proliferation, and differentiation

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How do cilia organize signalling cascades?

30 September 2017

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Mechanically induced osteogenic lineage commitment of stem cells

30 September 2017

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Primary cilia: the chemical antenna regulating human adipose-derived stem cell osteogenesis

30 September 2017

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Analysis of primary cilia in directional cell migration in fibroblasts

30 September 2017

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Primary cilia-mediated mechanotransduction in human mesenchymal stem cells

30 September 2017

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Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading

30 September 2017

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Endogenous bone marrow MSCs are dynamic, fate-restricted participants in bone maintenance and regeneration.

30 September 2017

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Disruption of Kif3a in osteoblasts results in defective bone formation and osteopenia

30 September 2017

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A role for the primary cilium in paracrine signaling between mechanically stimulated osteocytes and mesenchymal stem cells

30 September 2017

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The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment

30 September 2017

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Mesenchymal stem cell mechanobiology

30 September 2017

1 reference

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Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts

30 September 2017

1 reference

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Regulation of stemness and stem cell niche of mesenchymal stem cells: implications in tumorigenesis and metastasis

30 September 2017

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Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis

30 September 2017

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Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

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Intraflagellar transport

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Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis

30 September 2017

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Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

30 September 2017

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30 September 2017

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30 September 2017

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Primary cilia exist in a small fraction of cells in trabecular bone and marrow

28 June 2018

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5 September 2018

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5 September 2018

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5 September 2018

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5 September 2018

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12 December 2020

Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche

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12 December 2020

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction

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12 December 2020

Recruitment and proliferative responses of osteoblasts after mechanical loading in vivo determined using sustained-release bromodeoxyuridine

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Primary murine MSC show highly efficient homing to the bone marrow but lose homing ability following culture

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Identifiers

DOI

10.1096/FJ.15-276402

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26675708%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26675708%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

26675708

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26675708%20AND%20SRC:MED&resulttype=core&format=json